• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe |

Tryptamines Any reason to believe that Kratom would be dangerous to mix with 5-Meo-Mipt or 5-Meo-Dipt?

So LSA and Kanna is a bad mix? Kanna itself can be dangerous if mixed with certain substances I think. I am not sure if it is serotonin syndrome or another mechanism but have heard it should not be mixed with certain things. But would love to know the full scoop on that!

I remember years ago the diet restrictions that were to go along with harmalas and ayahuasca. Then Johnathon Ott wrote in his books that he ate cheese sandwiches and drank beer after also ingesting harmalas. Then the notion of a reversable MAOI not being as dangerous as say a non reversable came about. So it seems all of a sudden the diet restrictions that people were told to adhere to with harmalas are no longer as prudent. At least I think.

I would still treat harmalas as something to be aware of, and of what can be mixed with it.
I should've phrased it clearer sorry, health has been a clusterfuck recently and I'm barely hitting 1,000kcal/day so I'm very foggy. Both Kanna and LSA independently (or together) should never really be mixed with harmalas in my experience. Hbwr with ayahuasca damn near killed me twice. Kratom was fine though, and hodgkinsine is probably toxic on its own but my homie had a habit of insufflating harmaline crystals and doing huge dabs for the cross potentiation, and he had a very intense psychedelic dissociative experience introducing hodgkinsine to that mix, it seemed safe at least but we have no idea on what dose was in that tincture so IDK how to give any safe advice pertaining to hodgkinsine + harmalas, and imo there is no safe way to mix Kanna or lsa with harmalas, even though LSD, 4-substituted tryptamines, etc all mix beautifully.

If you're looking to boost phenethylamines, consider using hordenine for MAO-B inhibition vs harmaline's dominantly MAO-A inhibition.
 
I would please like to hear some follow ups on Mixing (not directly) but on a same day Kratom, and for example nn or 5-meo-dmt. I need the healing potential of Psilocybin for example. But I struggle with Chronic Back Pain whereby I am around a 15G per day Kratom user. It helps my pain immensely and seems to be stable in tollerence for the most part. I discovered the amount required for decent pain relief is a bit lower then the amount the brain craves for feel-good. I think the DMT has potential to rewrite some neuro-pathways and as we know

Our pain patterns can get caught up in a nervous system glitch whereby we need to break free of the pattern. Some times the Injury is healed but the pain pathway keeps firing? Does injury have a memory? Is this Neuroplastic pain? Need to erase the code! Then we have Psychosocial pain, pain tied to our environment (inluding people lol) Actually my pain is less generlaly around people -- if they are GOOD!

P.S. What is the difrerence between 5-meo-dipt and regular %-meow? I guess I will google it
 
I would please like to hear some follow ups on Mixing (not directly) but on a same day Kratom, and for example nn or 5-meo-dmt. I need the healing potential of Psilocybin for example. But I struggle with Chronic Back Pain whereby I am around a 15G per day Kratom user. It helps my pain immensely and seems to be stable in tollerence for the most part. I discovered the amount required for decent pain relief is a bit lower then the amount the brain craves for feel-good. I think the DMT has potential to rewrite some neuro-pathways and as we know

Our pain patterns can get caught up in a nervous system glitch whereby we need to break free of the pattern. Some times the Injury is healed but the pain pathway keeps firing? Does injury have a memory? Is this Neuroplastic pain? Need to erase the code! Then we have Psychosocial pain, pain tied to our environment (inluding people lol) Actually my pain is less generlaly around people -- if they are GOOD!

P.S. What is the difrerence between 5-meo-dipt and regular %-meow? I guess I will google it
I've mixed kratom with N,N-DMT, 5-MeO-DiPT, harmaline, tetrahydroharmine, a variety of 4-substituted tryptamines, Amanita, quite a few things tbh. The body does "remember" injury in certain ways, is that specifically what you're trying to address here?

Also what is regular %-meow? I'm quite familiar with 5-MeO-DiPT so could certainly provide a comparison if you elucidate what %-meow is.
 
Yeah I have mixed kratom (the leaf) with DMT,DPT,LSD, Salvia 2C-B, cactus. Probably more since it has been a bit. But just plain leaf, and average amount.

A few years back, more than once I would wake up early, have my kratom, eat half a bagel. Then toss and wash 30 gr of cactus skin powder. That is a lot of powder. But I get it done and eat two bagels with cream cheese. Bready stuff to absorb in the stomach. Have a few tokes of weed and wham......! mescaline!! All Day. No nausea at all. I wonder why people make a disgusting slop of cactus and gag when they can T&W.

Regular kratom leaf is pretty safe, BUT too many new things are labelled as kratom that may not be safe as plain leaf is. It pays to know what you are ingesting and even asking the question is wise.
 
Yeah I have mixed kratom (the leaf) with DMT,DPT,LSD, Salvia 2C-B, cactus. Probably more since it has been a bit. But just plain leaf, and average amount.

A few years back, more than once I would wake up early, have my kratom, eat half a bagel. Then toss and wash 30 gr of cactus skin powder. That is a lot of powder. But I get it done and eat two bagels with cream cheese. Bready stuff to absorb in the stomach. Have a few tokes of weed and wham......! mescaline!! All Day. No nausea at all. I wonder why people make a disgusting slop of cactus and gag when they can T&W.

Regular kratom leaf is pretty safe, BUT too many new things are labelled as kratom that may not be safe as plain leaf is. It pays to know what you are ingesting and even asking the question is wise.
I've personally had a much easier time with tea the one time I took that route (using Lophophora diffusa which is likely very unsafe, I now know), but tossing and washing anything grosses me out too much. I suspect a lot of it comes down to personal preferences.

I've mixed MGM-15, pseudoindoxyl mitragynine, mitragynine and 7-OH-mitagynine with far more psychedelics and empathogens than I have kratom leaf on its own, though often when I use one of those purified compounds I'll also throw some leaf in there since they play along together like the musicians of a symphony. The only thing that I have noticed being problematic in kratom/mitragyna alkaloid combinations is alcohol, GHB, and I would assume by extension all GHB prodrugs and analogs (GBL, 1,4-BDO, EAB, etc.).
 
I've mixed MGM-15, pseudoindoxyl mitragynine, mitragynine and 7-OH-mitagynine with far more psychedelics and empathogens than I have kratom leaf on its own, though often when I use one of those purified compounds I'll also throw some leaf in there since they play along together like the musicians of a symphony.
Nicely put. I love reading about mixes. Curious about mixing harmala and kratom. You know ayahuasca. But I think I remember you saying you have done that mix too. I have stayed away from harmala since daily kratom.

I don't worry about you mixing stuff Esper. ;) I read with interest. Although I do believe after reading posts that nobody has mixed the way you do. And cannabinoids too. On paper? Fascinating. I think I have a million questions. The mind wanders.

The only thing that I have noticed being problematic in kratom/mitragyna alkaloid combinations is alcohol, GHB, and I would assume by extension all GHB prodrugs and analogs (GBL, 1,4-BDO, EAB, etc.).
I can see alcohol, I never mix, although I stopped drinking for years. I never got to do GHB, it was on the shelves next to the vitamin C in sports shops and I wrote it off some years back. Magazines were calling it liquid ecstasy and I was like yeah yeah yeah. Now I am interested! But that looks like you have to be careful. From what I am reading GHB/BDO is safe to a point. Then I read people ended up in hospitals. A lot of care is needed.
 
I don't worry about you mixing stuff Esper. ;) I read with interest. Although I do believe after reading posts that nobody has mixed the way you do. And cannabinoids too. On paper? Fascinating. I think I have a million questions. The mind wanders.
Feel free to ask away dude! My main reason on being in this forum is to propagate information from my research and experiences, both using drugs on myself but also guiding trips for folks. Cannabinoids are a great mix with anything as long as you're the type of person who simply cannot get too high (meaning, you never get anxious or anything while intoxicated). Virtually every day of my life over the last decade, I have been habitually consuming cannabinoids via a variety of routes of administration. Recently though, a box mod with a ceramic core and a 6.5mL tank that I just infinitely refill with distillate and altnoid mixes has been my favorite. It's like having a perfectly configured dab rig in your pocket at all times, whereas somebody might take 10-15 hits off of a dab pen to get where they want to be, no more than 1-2 rips off of this gets them to the same place.

I can see alcohol, I never mix, although I stopped drinking for years. I never got to do GHB, it was on the shelves next to the vitamin C in sports shops and I wrote it off some years back. Magazines were calling it liquid ecstasy and I was like yeah yeah yeah. Now I am interested! But that looks like you have to be careful. From what I am reading GHB/BDO is safe to a point. Then I read people ended up in hospitals. A lot of care is needed.
GHB's biggest problem is its therapeutic index (the gap in dosage between where you feel it and where you overdose). It's really, REALLY close. In my opinion, somebody who may black out and compulsively redose in pursuit of a higher degree of euphoria, should never touch GHB. If you're not that type of person, I'd recommend giving it a shot but do not mix it with anything else that's even remotely sedative. I've mixed GHB with more stimulating/psychedelic combos before, meth, LSD, 2C-B, DOM, etc., but I would absolutely advise to never mix it with a benzo, or alcohol, or soma, and especially not barbiturates. The nickname of "liquid ecstasy" is honestly quite fitting in my opinion, GHB should be classed as a depressant/sedative first of all, but a VERY close second on that hierarchy of classification would be empathogen, in my opinion. It's also exceptionally pro-sexual, one of the horniest drugs I've touched in my entire life.

I don't want to go too far into it but the statute of limitations has long expired on it, but GHB manufacture was a relatively common practice among drug enthusiasts where I went to college, and most people (nearly all people) just self-supplied since it's so extremely cheap to do. GHB also induces a release of HGH (human growth hormone), so while I was also pinning HGH and taking HMB and a variety of other highly suspect supplements to help my main interest at the time which was powerlifting, I took really dangerously large doses of GHB every single night before bed so that I had yet another HGH agent working in my body.
 
I've mixed kratom with N,N-DMT, 5-MeO-DiPT, harmaline, tetrahydroharmine, a variety of 4-substituted tryptamines, Amanita, quite a few things tbh. The body does "remember" injury in certain ways, is that specifically what you're trying to address here?

Also what is regular %-meow? I'm quite familiar with 5-MeO-DiPT so could certainly provide a comparison if you elucidate what %-meow is.
Sorry, I am not sure why I was using the obscure slang for 5-meo-dmt.

That is interesting, I am even more curious about the Cross between Kratom and Harmalines it seems like a warned about area that rightfully has little research examples.

Thanks alot for sharing!

For me mostly trying to get an idea of safety and effect of having left over Kratom Alkaloids in system at 6 hour mark if choosing DMT of either variety.

However of course there seems to be an issue whereby Some people (not all) have muted DMT effects from Kratom? I am curious your experience but I think this would probably mostyl apply to daily regular users. The Competition at the Serotonin receptors is one idea behind this. Once again seems not a lot of data out there?
 
Sorry, I am not sure why I was using the obscure slang for 5-meo-dmt.

That is interesting, I am even more curious about the Cross between Kratom and Harmalines it seems like a warned about area that rightfully has little research examples.

Thanks alot for sharing!

For me mostly trying to get an idea of safety and effect of having left over Kratom Alkaloids in system at 6 hour mark if choosing DMT of either variety.

However of course there seems to be an issue whereby Some people (not all) have muted DMT effects from Kratom? I am curious your experience but I think this would probably mostyl apply to daily regular users. The Competition at the Serotonin receptors is one idea behind this. Once again seems not a lot of data out there?
I've never had kratom (nor 7-OH-mitragynine, pseudoindoxyl mitragynine, MGM-15, or mitragynine) detriment any psychedelics.
 
I've never had kratom (nor 7-OH-mitragynine, pseudoindoxyl mitragynine, MGM-15, or mitragynine) detriment any psychedelics.
Since 7-oh doesnt have the serotogenic affinity, that one would be less of my concern with competition at the 5ht1a or 2a receptors. But regardless I am glad to hear that
 
I remember years ago the diet restrictions that were to go along with harmalas and ayahuasca. Then Johnathon Ott wrote in his books that he ate cheese sandwiches and drank beer after also ingesting harmalas. Then the notion of a reversable MAOI not being as dangerous as say a non reversable came about. So it seems all of a sudden the diet restrictions that people were told to adhere to with harmalas are no longer as prudent. At least I think.

People who are on irreversible MAOIs eat cheese sandwiches and drink beer.

"Had some loaded up pizza at dinner, and a couple of glasses of red wine today lol."  TechnicalCatch  2024-05-26  reddit

"I have been [tranylcypromine] for like 30 years and long ago I forgot entirely about all that tyramine and preserved sausages and stuff like that, and yet here I am, happy and healthy"  pumbungler  2024-06-03  r/MAOIs

"It's very rare to have a hypertensive crisis while on MAOIs, but the danger is there and you can get one when you least expect it. Took me two years to find out how it felt like. I ate spoiled meat and it gave me a splitting headache, felt like my head was about to explode. Before that incident i had been eating everything and paid the diet no concern at all."

"I still don't care about the diet, but gourmet cheese and spoiled food should be avoided at all costs."

ChopSuey  2014-09-22  Re: MAOI "diet" by psychiatrists - a joke?

The dietary restrictions classically advised for patients taking oral MAO inhibitors were established to prevent hypertensive crises associated with tyramine ingestion. However, some of these restrictions were unsubstantiated,[38] and evidence from more recent studies suggests that they are unnecessarily strict[39]

[...]

Among the many foods determined to be unnecessarily restricted are avocados; bananas; beef or chicken bouillon; chocolate; fresh and mild cheeses, eg, ricotta, cottage cheese, cream cheese, processed cheese slices; fresh meat, poultry, or fish; meat gravy (fresh); monosodium glutamate; peanuts; properly stored pickled or smoked fish (eg, herring); raspberries; and yeast extracts (except Marmite).[39]


[...]

Absolute dietary restrictions include[39]:

• Aged cheeses and meats
• Banana peels
• Broad bean (fava) pods
• Spoiled meats
• Marmite
• Sauerkraut
• Soybean products
• Draft beers.


MAO Inhibitors: Risks, benefits, and lore. Wimbiscus, Molly M.D., Olga Kostenk, M.D., Donald Malone, M.D. Dec 2010. Cleveland Clinic Journal of Medicine, 77 (12) 859–882.  10.3949/ccjm.77a.09103  Diet can be more lenient than in the past, page 873
https://www.poison.org/articles/making-sense-of-mao-inhibitors  See bottom of page


Further reading: https://www.bluelight.org/community/posts/16419142
 
Top