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  • BDD Moderators: Keif’ Richards

Seroquel

streaM Freak said:
At this point i'd like to ask, are you using Seroquel to calm a stimulant binge? If so, as @andrey and @JackDick were saying, it can confuse your body and you may end up taking too much of either one.

This happens often.. with speedballs of coke and heroin, meth and GHB, cocaine and alcohol...

You mentioned earlier @Pirrracetamol , two downers like alcohol and Seroquel. Yeah, double downer or double upper is obviously dangerous. But so is trying to balance them out with and upper and downer. Because you will think you're functioning more normally than you actually are. You will probably feel good, to be honest, but your insides would probably be screaming at you to fucking stop, if your organs could talk.
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Using it for sleep
 
Pirrracetamol said:
Hey ho

Is seroquel an anxiolytic because they use them in prison I've read
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I will skip all the replies and fancy talk and just go

They use seroquel in prison to make the prisoners more pliable. "Thorazine zombies" Common (Well documented) practice in the medical and legal field to blunt problematic 'patients' mental and physical abilities with seroquel

they usually are considered having no recreational value. Prisoners do desperate things, honestly idk if Id prefer to serve my sentence at full brain capacity or as a thorazine zombie...
 
What's the bioavailability for insuffilation spelling? Of seroquel? I can't tell

I did google it pubmed had all these long words that didn't make sense and diagrams lol
 
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While precise human bioavailability percentages for intranasal Seroquel are unavailable, studies on specialized, medically researched nasal nano-formulations (not crushed tablets) in animal models demonstrate that optimized intranasal delivery systems can achieve a bioavailability between 89% and 95% while bypassing the blood-brain barrier for enhanced central nervous system targeting.

(NOT CRUSHED TABLETS) BUT -- The drug is primarily prescribed for oral use, which provides an oral bioavailability of approximately 9% due to extensive first-pass liver metabolism. [1, 2, 3, 4]

There is no established bioavailability I found for crushed tablets but the logic in my head says you would get significantly more(?).

I have accidentally snorted seroquel thinking it was percocet in highschool and idk what it woulda done orally but it was a very rough day.
 
streaM Freak said:
Right, it probably isn't as bad as benzos and alcohol.
And it has valid purposes.
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Bad in what sense? I disagree vehemently if the person does not choose to take it. Western Scopolamine. (Thats the zombie powder drug right)

You should read up on seroquel and its history if you think it isn't as bad as benzos --- alcohol, maybe. Alcohol is ranked the most harmful drug by the NICHS (Sp lol - studies about 10 years old now as well)

It has a valid purpose but so does a bullet; not recommended for everyone. Ironically the venn diagram of ppl they wanna get rid of between those two things ... nvm

Boku_ said:
sorta. you just get more grogggy
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I had a family member diagnosed with schizophrenia who is forced to take seroquel. That mofo puked if he had a drink in him every time. Like the family would warn you -- "If he drinks he pukes" and would say it was because of seroquel... I believed it but idk.
 
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notsmokeymcpot42088 said:
Bad in what sense? I disagree vehemently
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Benzos and alcohol are bad in the sense that you can easily overdose and also the withdrawals are horrible.

Seroquel on the other hand, I've been on for a couple years at one point in my life, was doing all sorts of drugs on it, stopped it, started it, I didn't have an issue aside from grogginess (and restless legs at a consistently high dose)

But that's not the main point. The main idea is that mixing downers and uppers doesn't give you a good idea on how fucked up you are.
 
Pirrracetamol said:
Well i was gurning last night and today and after I sniffed it it stopped not completely but a lot better than what it was.
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I figured -- if the are giving 9% oral (Which is horrible) than kind of being vague about any other method with a rough reference it can be 95% ...

I remember when I had a morphine (Like 15-30% oral) habit there was a study done with chitosan (on a nano level) that would up the snorted bioavailability to like 65%--- I bought a bottle of chitosan in diet pill capsules and ppl were buyin em up for 5 bucks to mix with they phine lines--- could absolutely have been placebo! Selling diet pills that were under a penny each for 5 bucks was prime though lol

If I have heard correctly; doesn't that shit burn a good deal? ( I mean who cares if you increasing the biovailability, not harming your nose, and you like more effects )
 
streaM Freak said:
Benzos and alcohol are bad in the sense that you can easily overdose and also the withdrawals are horrible.
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Point of fact you can not "Easily" overdose on benzo's. Nitrazepam aside..... I dont think 100 pills of the strongest formula of any 1.4 benzo would kill someone with no tolerance?? (check the LD50's im waiting for a correction) --- Now of course add any other CNS depressant and you got a fatal cocktail........... Withdrawal --- YUP YOU CORRECT. Ill take seroquel withdrawal any day over benzos or alcohol
streaM Freak said:
Seroquel on the other hand, I've been on for a couple years at one point in my life, was doing all sorts of drugs on it, stopped it, started it, I didn't have an issue aside from grogginess (and restless legs at a consistently high dose)

But that's not the main point. The main idea is that mixing downers and uppers doesn't give you a good idea on how fucked up you are.
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Grogginess and restless leg SUCK. I will medicate restless leg with benzos if it occurs. If we are aiming for recreation with minimal side effects ---- well I guess seroquel is better than nothing but id wait till I had 10 bucks and a benzo connect lol -- or just buy a bottle.

To each they own
 
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"Overdosed" in the medical term of taking more than you are prescribed -- falling into a deep sleep? (Ya woulda woke up)

DO TELL US THE STORY OF HOW BENZOS ALONE WOULD HAVE KILLED YOU? (again unless it was nitrazepam) ---- I will refute it with facts. *unless I lose the debate* (Nah not possible) lol....

streaM Freak said:
Jesus dude.

I've overdosed on benzos. And I've been on Seroquel for multiple years.

And even more interesting: most of what we're talking about the OP didn't ask about.
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PS -- I know a shit ton of ppl that "Tried to kill themselves" with benzos --- THANK GOD they didnt reach for the tylenol PM!!

Just personal experience -- anecdotal -- about 700mgs of xanax (equipotency) a day was fine but when I snorted 4 seroquels -- HORRIBLE DAY. (Admittedly 2 were real percocet 4 were seroquel and there was a field trip to the ski-hill) Not the place you wanna snort 4 seroquel than go to!
 
notsmokeymcpot42088 said:
I figured -- if the are giving 9% oral (Which is horrible) than kind of being vague about any other method with a rough reference it can be 95% ...

I remember when I had a morphine (Like 15-30% oral) habit there was a study done with chitosan (on a nano level) that would up the snorted bioavailability to like 65%--- I bought a bottle of chitosan in diet pill capsules and ppl were buyin em up for 5 bucks to mix with they phine lines--- could absolutely have been placebo! Selling diet pills that were under a penny each for 5 bucks was prime though lol

If I have heard correctly; doesn't that shit burn a good deal? ( I mean who cares if you increasing the biovailability, not harming your nose, and you like more effects )
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Actually, seroquel numbs mucous membranes, at least for me. I believe its because of the effect on th hERG receptor. This is also the receptor responsible for the fatal effect on the heart cells(qt prolongation) but im not entirely sure. Therefore, at such high doses seroquel has serious side effects and works very anti psychotic/dopaminergic. I.e. Horrible feeling. Literally anti euphoria since it blocks all the dopamine.
 
According to erowid.....the drug is also taken intranasally by snorting pulverized tablets. So it must have a high bioavailability or it wouldn't say that?
 
I hate seroquel its so uncomfortable. The reason they give it out in prison is precisely because it has no rec value
 
andrey said:
This is also the receptor responsible for the fatal effect on the heart cells
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What's this mean? Bad for the heart?
I can't have that as i have heart failure.
It can't be because why would they prescribe it to me?
 
Why are we snorting quetiapine? What's the actual goal? Honestly, my only bad experience with it is waking up next to an empty jar of peanut butter and a mountain of regret. And before you ask, no, I didn't have sex with the peanut butter. It gives you the munchies like nothing else... I'll take it once in a blue moon if I'm too manic (which rarely happens) or to back up my sleep meds to guarantee I catch some z's.
 
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