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  • BDD Moderators: Keif’ Richards

Seroquel

Pirrracetamol said:
Hey ho

Is seroquel an anxiolytic because they use them in prison I've read
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So simple to Google this.

Here you go, it took me a few seconds to type the question into Google.

Seroquel (quetiapine) is a second-generation atypical antipsychotic medication that possesses anxiolytic (anxiety-reducing) properties. While it is not a first-line or FDA-approved anxiolytic, it is commonly used off-label to treat anxiety disorders when traditional treatments are ineffective.

Key Points
  • Primary Indications: Seroquel is FDA-approved for the treatment of schizophrenia, bipolar disorder (manic, depressive, and maintenance episodes), and as an add-on treatment for major depressive disorder.
  • Off-Label Use for Anxiety: Prescribers frequently use it "off-label" to manage severe or treatment-resistant anxiety, particularly when it co-occurs with other mental health conditions. In fact, anxiety disorders represent its most common off-label use.
  • Mechanism of Action: Unlike traditional anxiolytics like benzodiazepines (e.g., Xanax), which work by enhancing GABA neurotransmitters, Seroquel works by balancing levels of dopamine and serotonin in the brain. Its active metabolite, norquetiapine, contributes to its anxiolytic and antidepressant effects by affecting norepinephrine and serotonin receptors.
  • Onset and Effectiveness: Seroquel's anxiolytic effects are typically gradual and not immediate, unlike rapid-acting medications like Xanax. Studies indicate it can have a modest impact on reducing anxiety symptoms, sometimes comparable to SSRIs, but it comes with a different set of potential side effects, such as significant drowsiness, dizziness, and weight gain.
 
I was put on sequel. It is definitely no fun. I helped my insomnia, but killed my sleep quality. I was diagnosed with sleep apnea (I start chocking/can't breath) and my brain wakes me up. This happens 30 times an hour. I am staring a CPAP tonight.

Seroquel also made me extremely forgetful. I would stay away from it unless absolutely necessary.
 
I was also on quetiapine for several years dosages from 300 to 900 mg a day. It's an horrible drug that knocks you out cold, leaving you running at night (akathisia) with acute Rest less leg syndrome even years after stopping it, after failed 5 times to quit. The WD was making me delirious even when tapering down. I never found anything good in this drug it just makes you sleepy, knocks you, then leave you groggy for half the day. One of the hardest med to quit in my case, pregabaline helped me that way.
 
@Pirrracetamol - maybe, probably better than Seroquel for being functional. Seroquel isn't really a pop and chill drug, it is one you take over an extended period to mitigate other things.

The prison thing, yeah I've heard of the "Seroquel shuffle", but as Keif was saying it's not really a fun drug. I've been on it a lot, from 50, to 200, and 800 a day once in the ward. From my understanding, it's taken in prison because it knocks you out to sleep and also just reduces background noise (figuratively).
 
streaM Freak said:
@Pirrracetamol - maybe, probably better than Seroquel for being functional. Seroquel isn't really a pop and chill drug, it is one you take over an extended period to mitigate other things.

The prison thing, yeah I've heard of the "Seroquel shuffle", but as Keif was saying it's not really a fun drug. I've been on it a lot, from 50, to 200, and 800 a day once in the ward. From my understanding, it's taken in prison because it knocks you out to sleep and also just reduces background noise (figuratively).
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R u talking bout magnolia bark
 
streaM Freak said:
@Pirrracetamol - maybe, probably better than Seroquel for being functional. Seroquel isn't really a pop and chill drug, it is one you take over an extended period to mitigate other things.

The prison thing, yeah I've heard of the "Seroquel shuffle", but as Keif was saying it's not really a fun drug. I've been on it a lot, from 50, to 200, and 800 a day once in the ward. From my understanding, it's taken in prison because it knocks you out to sleep and also just reduces background noise (figuratively).
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?
 
@Pirrracetamol - yeah, sorry, I don't know anything beyond what googles first page knows about it though. It is what I was referencing when saying probably more functional than Seroquel.

Looks like magnolia bark could cause blood thinning and can potentiate downers, but if that isn't something that is concerning to your particular situation than id say it sounds nice and calming, no not like a benzo (which has more "pleasure" on top of the calming), but calming can in itself be pleasurable if that's what you seek
 
streaM Freak said:
@Pirrracetamol - yeah, sorry, I don't know anything beyond what googles first page knows about it though. It is what I was referencing when saying probably more functional than Seroquel.

Looks like magnolia bark could cause blood thinning and can potentiate downers, but if that isn't something that is concerning to your particular situation than id say it sounds nice and calming, no not like a benzo (which has more "pleasure" on top of the calming), but calming can in itself be pleasurable if that's what you seek
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I'm on blood thinners so that's a no go.
 
Its a horrible drug. Of course, it has its uses for schizophrenia or bipolar disorder, but it has so many side effects; its not worth it to take it for anything else than the official indications.

Ive been taking it for insomnia for three years soon and it doesnt help really. But my side effects are severe: i cant sit still for more than a minute; I had a racing heart for hours after being ill and taking my normal seroquel dose; I have sometimes severe constipation because of it; and I started developing EPS(my tongue is twitching and hurting).

There are so many other sedating anti histamines you could try, so I would definitely stay away from any neuroleptic if I was you.
 
Seroquel makes you groggy and also increases your appetite alot on the next day.

It really does help to fall asleep and calms down effects of other drugs.
Beware, that using it before you had use stimulants (or some other drugs too probably), makes
the body receive contradictory signals, and this is unhealthy for the heart (or something like that)
 
Pirrracetamol said:
How do I combat seroquel dick from the night before?
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At this point i'd like to ask, are you using Seroquel to calm a stimulant binge? If so, as @andrey and @JackDick were saying, it can confuse your body and you may end up taking too much of either one.

This happens often.. with speedballs of coke and heroin, meth and GHB, cocaine and alcohol...

You mentioned earlier @Pirrracetamol , two downers like alcohol and Seroquel. Yeah, double downer or double upper is obviously dangerous. But so is trying to balance them out with and upper and downer. Because you will think you're functioning more normally than you actually are. You will probably feel good, to be honest, but your insides would probably be screaming at you to fucking stop, if your organs could talk.
 
streaM Freak said:
At this point i'd like to ask, are you using Seroquel to calm a stimulant binge? If so, as @andrey and @JackDick were saying, it can confuse your body and you may end up taking too much of either one.

This happens often.. with speedballs of coke and heroin, meth and GHB, cocaine and alcohol...

You mentioned earlier @Pirrracetamol , two downers like alcohol and Seroquel. Yeah, double downer or double upper is obviously dangerous. But so is trying to balance them out with and upper and downer. Because you will think you're functioning more normally than you actually are. You will probably feel good, to be honest, but your insides would probably be screaming at you to fucking stop, if your organs could talk.
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Well, I know quite a few people who took seroquel besides their drug consumption; and they are doing fine overall.

What you are saying can happen, but thankfully seroquel isnt a potent depressant like benzos or alcohol.
It will still mess with your metabolism in long term and its best to stay away from it if you dont have any serious symptoms.

Doc prefer using it because its still a potent sedative, its cheap and easy accessible. Still genuine and knowledgeable health experts warn about its use outside of the official indications and they are totally right.
 
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