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Coming off Invega/Xeplion (paliperidone) injections v 12

anonymoususer777 said:
I was waking up unrested at month 5... now in month 8, that is one problem that is solved ..i feel more rested after sleep even though i still have sleep disruptions. I think we have to wait some more.
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I only have 3 hours of sleep with zopicolone, without it i cant even sleep and i dont know what to do anymore, i wake up and wait to have 3 hour sleep, how is that bearable? I cant stay awake 21 hours without doing single thing
 
important update: i just reported my side effects to an organisation for adverse reactions to medication, it’s called BNF, if more people reported this to equivalent organisations in their countries, so many less people would have died and suffered

there’s been thousands of people who took paliperdione and there’s been hundreds in this forum, people could have took action and instead of being complacent, it genuinely infuriates me!?

at least I did my duty, just wish more people did theirs :(
 
twinpeaks123 said:
important update: i just reported my side effects to an organisation for adverse reactions to medication, it’s called BNF, if more people reported this to equivalent organisations in their countries, so many less people would have died and suffered

there’s been thousands of people who took paliperdione and there’s been hundreds in this forum, people could have took action and instead of being complacent, it genuinely infuriates me!?

at least I did my duty, just wish more people did theirs :(
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Bro it doesn’t change anything there is so much profit in injections and they wont do shit about it, its all bullshit you think 10 years of threads did anything?
 
moerez said:
Bro it doesn’t change anything there is so much profit in injections and they wont do shit about it, its all bullshit you think 10 years of threads did anything?
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because no one wants to take action, when people recover, they just move on and forget all this, i don’t deny it’s traumatic but all it took for me was a phone call and I haven’t even recovered yet
 
RisperdalConsta50mg said:
in 10 days i will hit 19 months without recovering… In 4 days i will reach 2 months in the psych ward and there is nothing they are doing to help me a part giving temesta for severe anxiety and mirtazapine to help sleep/depression, but i’am not depressed as a mental illness, i’am just “not happy” because of the sympthoms that these injections left me with. And tinnitus keep me waking up during night and very early in the morning like 5AM.. Almost 19 months..
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The fact that you cannot feel alcohol, caffeine, or nicotine could be a hint. Whatever stops a person from feeling substances after antipsychotics is possibly where we can start fixing the problem. If you cannot feel substances than it is unikely you will feel the effects of drugs like vyvnase.
 
anonymoususer777 said:
The fact that you cannot feel alcohol, caffeine, or nicotine could be a hint. Whatever stops a person from feeling substances after antipsychotics is possibly where we can start fixing the problem. If you cannot feel substances than it is unikely you will feel the effects of drugs like vyvnase.
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So I’am cooked?
 
anonymoususer777 said:
NO, just trying to find out why antipsychotics prevent a person from feeling the effects of weed, alcohol, caffeine, nicotine etc.. finding the answer to why may lead to a solution
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Because we all cooked, feeling substances doesn’t mean you heal or something, its just shows the damage was so high that your reward system is completely off, i still cant feel anything as 5 months passed and poision should already been out of my body, trueart can work and be functional and im still vegteable, it means we are cooked and there is no way to get better time just makes us used to it thats it
 
moerez said:
Because we all cooked, feeling substances doesn’t mean you heal or something, its just shows the damage was so high that your reward system is completely off, i still cant feel anything as 5 months passed and poision should already been out of my body, trueart can work and be functional and im still vegteable, it means we are cooked and there is no way to get better time just makes us used to it thats it
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Turning on the reward system could be a step towards fixing the rest of the brain. We are all alive due to hope, and any treatments that give us hope need to be talked about and investigated not instantly shut down by people like you.

I am sure trueart struggles at his job due to invega. I did too.

The drug does not leave the body in 5 months, i dont think this is true. I think the drug stays in the body for many more months, probably a year and may stay in fat deposits later too. The brain still recovers many months afterwards when the drug concentration is very low in the blood.
 
anonymoususer777 said:
Turning on the reward system could be a step towards fixing the rest of the brain. We are all alive due to hope, and any treatments that give us hope need to be talked about and investigated not instantly shut down by people like you.

I am sure trueart struggles at his job due to invega. I did too.

The drug does not leave the body in 5 months, i dont think this is true. I think the drug stays in the body for many more months, probably a year and may stay in fat deposits later too. The brain still recovers many months afterwards when the drug concentration is very low in the blood.
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What kinda treatment can focus on reward system? Literally nothing! I went to many doctors and they just prescribe ssri and thats it because they know there is nothing you can do about it.
Honestly the half life says 4-8 months and many people who recover notice improvement after 5 months, i wish i had your hope that we become better but its just falsehope or atleast i can say i individually know that i dont get better maybe gain 10% of what i am, even IOSIP who recovered was able to do some stuff at 5 months , i literally cant walk and feel paralyzed , my symptoms are worse than anybody in here and i know my faith is to end this shit unfortunately. But i hope you guys get better soon
 
moerez said:
What kinda treatment can focus on reward system? Literally nothing! I went to many doctors and they just prescribe ssri and thats it because they know there is nothing you can do about it.
Honestly the half life says 4-8 months and many people who recover notice improvement after 5 months, i wish i had your hope that we become better but its just falsehope or atleast i can say i individually know that i dont get better maybe gain 10% of what i am, even IOSIP who recovered was able to do some stuff at 5 months , i literally cant walk and feel paralyzed , my symptoms are worse than anybody in here and i know my faith is to end this shit unfortunately. But i hope you guys get better soon
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The half-life is 25 to 50 days. On average it is 42 days. It takes about 8 half lives for the drug to reach a level low enough but sensitive brains can take even longer. I struggled to even stand sfter they gave me the drug. Psychiatrists are no help, and never take ssris. We need to find out the science of why the reward system in the brain is disrupted and how we can restore it.
 
anonymoususer777 said:
The half-life is 25 to 50 days. On average it is 42 days. It takes about 8 half lives for the drug to reach a level low enough but sensitive brains can take even longer. I struggled to even stand sfter they gave me the drug. Psychiatrists are no help, and never take ssris. We need to find out the science of why the reward system in the brain is disrupted and how we can restore it.
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Why some people recover in 6 months and some never? Its not the drug clearance it depends on the damage and how brain process it, many people sleep alot on this drug i cant even sleep to let my day go , im in pain and nothing can change that, im totally screwed and fuck my life i have to finish myself i dont want to die though i really dont, but i know there is no recovery for me
 
moerez said:
Why some people recover in 6 months and some never? Its not the drug clearance it depends on the damage and how brain process it, many people sleep alot on this drug i cant even sleep to let my day go , im in pain and nothing can change that, im totally screwed and fuck my life i have to finish myself i dont want to die though i really dont, but i know there is no recovery for me
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Its been only 5 months and people who recovered even later have allbeen where you are.
 
moerez said:
Are you still same in terms of invega side effects even after two years or you only have pssd? Because if i think that way that i have to wait for 2 years to recover from invega i eventually gonna finish my self since i cant wait for 2 years to get fixed
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You will probably be fine in a year, please don't try an SSRI to get better because it won't help and it will only put you at risk for PSSD. Taper off the SSRI no matter how long you were taking it.
 
anonymoususer777 said:
Its been only 5 months and people who recovered even later have allbeen where you are.
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I haven’t found single person who gets worse after 5 months, its only people who dont recover, i almost cry everyday from this torture and to be honest my friend all im thinking is finish my self so i dont take this pain anymore, i really cant wait for one year when i cant sleep or do anything during the day, i just wake up from 6 am and doing nothing until its night and i sleep for 3 hours and thats it, how am i supposed to cope like that
 
moerez said:
I haven’t found single person who gets worse after 5 months, its only people who dont recover, i almost cry everyday from this torture and to be honest my friend all im thinking is finish my self so i dont take this pain anymore, i really cant wait for one year when i cant sleep or do anything during the day, i just wake up from 6 am and doing nothing until its night and i sleep for 3 hours and thats it, how am i supposed to cope like that
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If i dont recover, i may also commit suicide. But we have to wait and cope however we can. There are many people who felt worse in many aspects after 5 months. Some people experience waves and windows continously.
 
anonymoususer777 said:
NO, just trying to find out why antipsychotics prevent a person from feeling the effects of weed, alcohol, caffeine, nicotine etc.. finding the answer to why may lead to a solution
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Severe damage to the brain. Blocked receptors,downregulated receptors,some parts of the brain could be damaged,low prolactin and testosterone. This is very insane.
 
deathbypsychiatry said:
Here's my list. It's pretty thereotical but behavioral factors are likely going to have the best results. When done for a couple months they should also induce neuroplasticity and gene expression changes in the right direction. Gene expression happens over weeks and takes months to lock in gains so theoretically keep up healthy habits for a few months and you're good.
Helpful:
Low dose stimulants/buproprion (if perscribed)
Ketamine therapy (if perscribed)
MAOIs should only be used short term (if perscribed)
Even low dose alcohol/cannabis infrequently
Drug based interventions only work when paired with behavioral factors during plasticity windows like:
Exercise (Aerobic, high intensity short duration 30-60 minutes. Think running, cycling. Maybe start with daily walks, then powerwalks and work up to it over a few weeks)
Novelty & learning
Goal-oriented tasks with immediate feedback
Mindfulness / attention training
Deep consolidated sleep

Harmful:
High dose stimulants
Chronic exposure to MAOIs
Poor sleep
Chronic or high dose alcohol/cannabis
Caffeine/Nicotine

The Thr75 thing i posted suggested forskolin will dephosphorylate Thr-75
Thr-75 is probably much worse on partial antagonists and its only theoretical.
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Is getting back to your old self not possible without these excercises? Does itnot happen automatically? Do we eventually become our old selves again?
 
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