Cycle Advice Megadosing Aspirin

High-Dose Aspirin Experiment (4g/day). Hans Amato. 2025-09-12. hansamato.substack.com

Clinical trials safely used 9g of aspirin daily for 30+ days.

I did 4g for 2 weeks and my testosterone maxed out the lab's upper limit.


h‍ttps://x.com/HansAmato/status/2007836970911739952
Do you have anything less pseudoscience-y than this? That dude doesn’t really provide any evidence for anything he says beyond “trust me bro”.

Also, I’m not sure if baking soda will make up for the decreased gastric mucous production due to aspirin. It doesn’t cost the stomach lining like gastric mucous does, it just transiently raises stomach pH.

Salicylates in general uncouple the proton gradient in the mitochondria at high doses. This is a reason for their relatively higher acute toxicity of aspirin compared to other NSAIDs like ibuprofen.

The figures in the 1977 baking soda and aspirin paper shown in that link reveal two points.

They did this experiment using 2 100 mg aspirin pills. This does not generalize to 4 grams of aspirin per day.

The stomach damage after an hour with the baking soda was still greater relative to their control.

This means that for even 200 mg of aspirin, co-administration of baking soda is insufficient to prevent all GI damage.
 
If asprin plus baking soda raised your test levels i would have been arnie size back in my binge drinking days
 
If you've never had a heart attack before, the feeling is like being under water and needing to breathe, only you're not under water. It hurts like Hell.
 
Well the president of the US gives megadosing aspirin two bruised handed thumbs up (Than blames the aspirin lmao) --- so who am I gunna listen to, you science nerds. (insert appropriate amount of sarcasm)
 
Why would you do this? Youll just cause yourself blood thinning and risk GI damage. There are significantly better ways to increase testosterone

HcG + Enclomiphene will bring you up to potentially 1400ng/dl+ without causing testosterone supression while improving fertility parameters increasing spermatogenesis and testicular size
 
If it increases T then I'm worse off than I thought. Since I eat this stuff like candy and have for years. You're just going to end up with GI problems this is stupid.

The only people I know that mega-dose aspirin on purpose are wrestlers that cut their foreheads 6 times a week to bleed for their matches. Something that isn't very common anymore at least in major wrestling organizations.

Sounds like a horrible idea. Don't do this it's stupid. Getting on the juice would be much preferable.

This reminds me I need to buy another 150 count bottle of the stuff. I get pretty depressed every time I notice how many of these things I've been eating a day. Not very healthy but I worry about acetaminophen raping my liver since I abused drugs that contained it so heavily in the past. Asprin is the only thing I've found that can stop my usual headaches.
 
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