At a long term tolerant patient with chronic pain due to RA ….I’ll say, a properly formulated/customized hybrid oral Brompton Cocktail
Oxycodone (Oxy-IR 5/10/20mg) scored tablets
Pregabalin 300-450mg in a fasted state (1h C-max) vs 4h after heavy meal
Diazepam 10mg - potent anxiolytic & muscle relaxant
Alprazolam 1mg - Potent anxiolytic + mood-boosting & antidepressant properties
Ritalin (Methylphenidate) 20mg X 2-3 tablets. Safe & effective robust Dopaminergic stimulant with identical MOA as Cocaine and actually compete for the same binding sites at the dopamine transporter
All tablets and capsules pulverized into fine powder……add 1.oz of HOT water to dissolve everything in milky white solution….add 1/3 cup sweet orange juice to mask bitter tast……..drink and in 30min onset will gradually creep in. 45min to 1 hour I’m melted to touch having Gin cocktails and relaxing pain free with SIGNIFICANT mood-boosting effects and a warm blanket of familiar Euphoria and psychological relief, mental stress relief
The Oxycodone + Ritalin (dopaminergic stimulant) actually enhance the painkilling properties of both compounds
Pregabalin is great for anticonvulsant & anxiolytic relief…of coarse the benzodiazepine Valium & Xanax definitely erase all anxiety, muscle relaxation and mood-boosting properties with antidepressant relief
Eukadol (Oxycodone) is the most euphoric opioid on earth. Period. A non-sedating theBaine derived compound with actually moderately stimulating properties…..unlike the sedating Morphone type opioids. Amazing oral bioavailability and VERY potent analgesic opioid narcotic compound……only downside, it’s reliability to enduce profound Euphoric Bliss
Oxycodone
Dilaudid (Hydromorphone) - Teir 1 POTENT water soluable full agonist slightly more potent than Diacetylmorphine (Heroin) — Dilaudid IR 2/4/8 tablets are great too…..but 30% oral bioavailability. Fck that noise
Only Pharmaceutical grade Sandoz Canada Hydromorphone HP FORT / 10ml glass vial with 1,000mg of HM….ya, that’s a sickening 100mg of Hydromorphone in a single 1cc / 1ml 29/30 gauge insulin syringe……POTENT HIGHLY RESPECTABLE OG injectable Opioids
Diacetylmorphine - Diamorphine (Heroin) 5/10/30/100/500mg vials ….Swiss Manufacturer Diacetylmorphine Hydrochloride 10 gram glass bottle of freeze dried HCL powder (10,000 mg of pharmaceutical Diamorphine)
Methadone (Dolophine) 1/5/10/25mg tablets and in US - cross scored 40mg wafers METHADOSE . Amazingly potent fully synthetic opioid with a long half life ….high oral bioavailability 60-80%