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Opioids SR-17018 and euphoria

Josephine_Morphine

Josephine_Morphine

Greenlighter
Joined
Mar 26, 2024
Messages
27
I've read extensively about this compound's unique properties, but what about it's euphoric potential? Will it get you as high as 7OH? More? I've heard it's much longer lasting, I can get two hours out of 7OH where it diminishes rapidly after two hours, I've heard SR 17018 is much longer lasting, how much?

I've found a reliable source, it's really expensive but If I can dose this three or four times compared to the six or seven times I have to dose 7OH it will be worth the increased cost. Suboxone has basically zero buzz . I hope SR17018 is not like that
 
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I don't know as much as some, but from my understanding the euphoria is actually less than 7 rather than more. I thought that was almost part of the draw from a harm reduction standpoint, then again I think anyone who doesn't think it will be abusable is living in a wishful fantasy, if you take enough, and hit your receptors hard enough, its bound to give some degree of euphoria.
 
From what I've seen from others experiences SR-17018 produces very little recreational effects, and people are primarily using it to painlessly withdraw from fent/zines/other opioids. As it heavily limits dependency and as far as I know doesn't produce wds itself
 
There isnt any euphoria and you will still get some cravings. On the physical side of withdrawal, the SR will take care of that. You do still feel low on energy etc the first couple of days. I used it to rapidly decrease my oxy dose and then jumped off the oxy and used just SR to help mitigate the withdrawals.
 
No, SR 17018 does not produce any sort of euphoria or even mood lift when done on its own, even with a naive or extremely low opiate tolerance. It simply takes withdrawals away and is a non competitive partial agonist. Sr 17018 also seems like it blocks /mutes opiates for a few days after. I did like 250mg of ODSMT oral and then boofed 100mg an hour later and felt ZERO effects the day after I used Sr 17 for 2 weeks, only dosing once or twice a day (usually 120-90mg)
 
noclipuser said:
No, SR 17018 does not produce any sort of euphoria or even mood lift when done on its own, even with a naive or extremely low opiate tolerance. It simply takes withdrawals away and is a non competitive partial agonist. Sr 17018 also seems like it blocks /mutes opiates for a few days after. I did like 250mg of ODSMT oral and then boofed 100mg an hour later and felt ZERO effects the day after I used Sr 17 for 2 weeks, only dosing once or twice a day (usually 120-90mg)
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Thats fascinating, I thought it would have at least a little bit of "warmth" to it, if nothing else. Like kratom maybe.
 
GooberDoober said:
Thats fascinating, I thought it would have at least a little bit of "warmth" to it, if nothing else. Like kratom maybe.
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Unfortunately it doesn’t, because it’s a very selective opiate that favors g protien signaling over the stronger beta arrestin which produces all the classic opiate side effects. However, Sr 17018 is only a partial agonist, but it has a brother called Sr 14968 which is a FULL agonist. Reports vary wildly tho, but doses for most users seems to 5-15mg and they report full on nodding and sedation. However when I received a 100mg sample of Sr 14968 I didn’t feel shit from a 25mg dose followed by a 60mg dose the next day. I have 500mg of it sitting in my drawer, don’t know when I’ll experiment more with it. But I’ve also read it took some users 100-300mg to get any effects. I just really want to get high off my ODSMT but this fucking SR 17 appears to be blocking any noticeable effects. Hopefully I’ll feel it tomorrow.
 
Josephine_Morphine said:
I've read extensively about this compound's unique properties, but what about it's euphoric potential? Will it get you as high as 7OH? More? I've heard it's much longer lasting, I can get two hours out of 7OH where it diminishes rapidly after two hours, I've heard SR 17018 is much longer lasting, how much?

I've found a reliable source, it's really expensive but If I can dose this three or four times compared to the six or seven times I have to dose 7OH it will be worth the increased cost. Suboxone has basically zero buzz . I hope SR17018 is not like that
Click to expand...
can you pls send me your source and let me know if it worked for 7oh
 
There have been at least two BLers who reported typical opioid subjective effects if SR-17018 is consumed at doses (substantially) higher than the dose required to prevent AWS. This is likely a simple case of YMMV.

Be aware that one known issue with SR-17018 is it's unreliable pharmokinetics. While it's always a good idea to reseach ANYTHING you are considering consuming, but be aware that on social media platforms discussants describe highly variable dosing requirements between individuals. A critical safety concern raised across multiple discussions is the risk of fatal overdose if individuals return to opioid use after their tolerance has been reduced by SR-17018. There appears to have been fatalities if people resume consumption of other 'classic' opioids.

https://sci-hub.st/10.3390/molecules26154509

There are a lot of recent academic papers on this compound, above is just a reasonable cross-section.

I declare I have no conflict of interest. I am not nor never have been employed, consulted, paid or otherwise recieved recompense from any party involved in the production, distribucion, promotion or sales of any opioid.
 
BTW the above are almost all theoretically behind paywalls so cannot be accessed by an AI. I just use Sci Hub to get them. I don't know if an AI can be trained to use Sci Hub but suspect not as even Sci Hub (an underfunded but massively supported database) has repeatedly been taken off-line by those who seek to charge for knowledge. A system I dispise as knowledge SHOULD be free. But no AI company would want it discovered that they had taken what is officially assigned a monetary value.
 
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