Opioids Promethazine Methadone Combo?

[IWantFentanylInMyShit]

I've had a benzo and painpill habit for about 4 years now. In and out of relationships and homelessness and all that of the sorts. My guy gets prescribed a lot of good shit and I'm SOL on the percs until friday. I was able to get some methadone though. I've had methadone before and I'm not the biggest fan of it. It doesn't get me nodding off in the same way that other opioids do. I'm also very sensitive to serotonin. a point of molly will get my jaw vibrating and my pupils blown to oblivion. I prefer dissociatives but I can't dissociate off of DXM because it's serotonergic effects get too powerful and overwhelming before I feel comfortable enough to take a good enough dose to dissociate. Just even the small serotonergic effects of methadone is enough to make colors brighter and for things to have a fuzzy outline. Methadone makes my touch sensitive and overall isn't really the high I'm looking for when I do opioids. My guy also gets prescribed promethazine. Is there a good synchronization I can get by combining the two? Do they synchronize? Is there any dangers? I don't mind falling asleep and not waking up. I just don't want any seizures or nausea.

 

[Dextro .45]

Me too…..oral Brompton Cocktail

Opioid narcotic
Dopaminergic stimulant
Benzodiazepine
Gabapentinoid
Ethanol
Cigarettes

Methadone 100-125mg
Ritalin (Methylphenidate) 50-70mg IR
Diazepam 30mg
Alprazolam 1mg
Pregabalin 300mg
Gin 2.oz per drink + Belmont cigarette

45min onset and I’m fckn FADED in euphoric ecstasy

 

[goodjunkie]

I've had a benzo and painpill habit for about 4 years now. In and out of relationships and homelessness and all that of the sorts. My guy gets prescribed a lot of good shit and I'm SOL on the percs until friday. I was able to get some methadone though. I've had methadone before and I'm not the biggest fan of it. It doesn't get me nodding off in the same way that other opioids do. I'm also very sensitive to serotonin. a point of molly will get my jaw vibrating and my pupils blown to oblivion. I prefer dissociatives but I can't dissociate off of DXM because it's serotonergic effects get too powerful and overwhelming before I feel comfortable enough to take a good enough dose to dissociate. Just even the small serotonergic effects of methadone is enough to make colors brighter and for things to have a fuzzy outline. Methadone makes my touch sensitive and overall isn't really the high I'm looking for when I do opioids. My guy also gets prescribed promethazine. Is there a good synchronization I can get by combining the two? Do they synchronize? Is there any dangers? I don't mind falling asleep and not waking up. I just don't want any seizures or nausea.

promethazine will actually help with nausea, as it is also recommended for motion sickness. the combo is not likely to cause seizures.
i am also sensitive to serotonin as i found out the other day i had a seizure from methadone+600mg palexia tapentadol is a no no

 

[IWantFentanylInMyShit]

Me too…..oral Brompton Cocktail

Opioid narcotic
Dopaminergic stimulant
Benzodiazepine
Gabapentinoid
Ethanol
Cigarettes

Methadone 100-125mg
Ritalin (Methylphenidate) 50-70mg IR
Diazepam 30mg
Alprazolam 1mg
Pregabalin 300mg
Gin 2.oz per drink + Belmont cigarette

45min onset and I’m fckn FADED in euphoric ecstasy

Ritalin will get me into a cold sweat and I need at least 4 mgs alprazolam to feel "high" off it anymore. Gabapentanoid plus methadone sounds cool tho. Good to know it won't kill me.

 

[Dextro .45]

You can take low dose Vyvanse (Lisdexamfetamine) 20mg …in 3h metabolizes into 5.9mg of d-Amphetamine

Ritalin 5mg is the lowest dose….very gentle. After 20 years my tolerance is 50-70mg IR …but in a cocktail that takes off any edge …but Methylphenidate is the safest dopaminergic stimulant compared to the Amphetamines especially Adderall or racemate Amphetamine

 

[IWantFentanylInMyShit]

You can take low dose Vyvanse (Lisdexamfetamine) 20mg …in 3h metabolizes into 5.9mg of d-Amphetamine

Ritalin 5mg is the lowest dose….very gentle. After 20 years my tolerance is 50-70mg IR …but in a cocktail that takes off any edge …but Methylphenidate is the safest dopaminergic stimulant compared to the Amphetamines especially Adderall or racemate Amphetamine

Id rather take cid if I want to be stimulated for 12 hours. Im really not an upper kind of guy. I don't want to lose the game. (You lost the game btw). I just want to forget. I can't even sleep without hearing LITERAL explosions caused by humans to make their 2 ton vehicle hurdle at 80 mph. Humans need to calm tf down. People out here sparking fires and yelling and going 120 mph miles above the sky so they can go gamble in Vegas with all the lights. Id rather snort some perc, pop some xans, drink some alcohol, nod off and see if I wake up (I always do) if I wanted to feel every breath I take and think about where I am and what I can do with my surroundings, id just take acid. I've done ritalin/methylphenidate, and it keeps me here, human, focused. Man im trying to find fent so I can od. My family is lucky I can't come across it. I buy xans off the streets and off the deep web and people freak out and im like "don't get my hopes up" (see name) I'll do a Ritalin if it has anything to do with my name. This is a harm reduction site but I guess thanks for letting me know about that cocktail or more so the knowledge that I can mix those things "safely"

 

[IWantFentanylInMyShit]

promethazine will actually help with nausea, as it is also recommended for motion sickness. the combo is not likely to cause seizures.
i am also sensitive to serotonin as i found out the other day i had a seizure from methadone+600mg palexia tapentadol is a no no

Molly freaks me tf out at first then I have the best time I've ever had in my life. With you also being sensitive to 5-HT, is Molly similar?

 

[Keif' Richards]

Me too…..oral Brompton Cocktail

Opioid narcotic
Dopaminergic stimulant
Benzodiazepine
Gabapentinoid
Ethanol
Cigarettes

Methadone 100-125mg
Ritalin (Methylphenidate) 50-70mg IR
Diazepam 30mg
Alprazolam 1mg
Pregabalin 300mg
Gin 2.oz per drink + Belmont cigarette

45min onset and I’m fckn FADED in euphoric ecstasy

You douchebag

Is this seriously the second time your first suggestion to a thread was a poly-substance drool fest. You're going from 0-60 a little too quick my friend.

@IWantFentanylInMyShit way to pick a name that speaks the truth of your heart.

Could you please tell us what specific side effects you're experiencing from the Methadone? That would help us narrow things down.

Promethazine (Phenergan) is a well-known and documented substance that is used frequently with Opioids for the subjectively "better" experience.

Ive gone in depth in other threads on this phenomenon. Sedative antihistamines, I believe, through their relatively minor sedative action on the nervous system, create a psychosomatic loop that makes us feel like we are higher.

Placebo is a relevant topic. If our bodies "feel high" our brains can relax and say "okay good, we're high".

That is my theory on the sedative antihistamines. They are great for relieving itch as well.

 

[Dextro .45]

lol…..ahhh, I’m sorry brother . I shouldn’t be advising people my 20+ years of tolerance to my legally scripted meds for chronic pain.

It really is a god send if needed, tolerance according

And yes….there are the standard low therapeutic doses for all substances

Perhaps I shouldn’t come on here after my Brompton Cocktail has reached its C-Max

My bad

 

[Dextro .45]

Oh…..Methadone oral drinks was initiated at 30mg daily after 7+ years of Oxycodone & Hydromorphone. My family doc then scripted me Methadol tablets (Methadone HCP USP) 25mg tablets X 100 tablet sealed bottle …Canadian Methadone tablets 1/5/10/25mg …..in the US those beautiful 40mg cross scored white or orange wafers rock

75mg for years, currently 75mg at 6am before breakfast…..home from work, another 50 or 75 depending on pain levels. Although its long half life of 24h it’s actual analgesic effects are 6-8h strong tapering off at 10h

Long term opioid use reduces testosterone levels in men, so after loosing interest in sex 10+ years ago I have a script for depo-Testosterone 200mg IM / 2 weeks

Methadone over 100mg can become an issue due to heart rhythm etc…….Levo Methadone prescribed in Germany doesn’t have this issue racemate Methadone has in high doses

Levo-Methadone 40mg
Racemate Methadone 80mg …..both equal Mu-Opioid Agonist binding / strength

Too much you’re mildly sedated……I really don’t take more than needed, less is more, paired with a safe dopaminergic stimulant such as Ritalin (Methylphenidate ) reduces sedation and improves cognitive function and enhances analgesic properties of the opioid narcotic

The Royal Brompton hospital just didn’t pull this out of their hat…..there is obviously medical science behind the madness ….and yes, it’s safe to add low therapeutic doses of Diazepam & Pregabalin according to body weight, fasting state, tolerance, genetic makeup (liver enzymes), etc…..know your DDI’s

Educated myself by reading medical journals like they were going outta style and honestly made a few docs look like fckn retards……seriously doc, you can’t tell me the delivery system & MOA of BIPHENTIN you’re prescribing me?

Fuuuuck……can I please have my lifelong tall white European doctor of 20 years back.

Sold his practice & client list to some Chinese Fck, dumped em, now some Indian tool that’s…….well.

Do yourself a favour and ask your doc for a referral to a PAIN SPECIALIST who’s educated in all analgesic medicine

Just Fck off, write my script with 7 repeats so I don’t have to see you for 5 fckn months, and take it eaz


……and that’s that.

Purolator will be arriving shortly with my 1,000mg of Avizafone (Pro-Diazepam) in which I’ll IM administer 80mg into my shoulder after selecting a suitable movie or documetary……hey man, it’s my day off

 

[IWantFentanylInMyShit]

Homelessness sucks. Hang in there.

Thankyou, I've gotten out of it before. Girls just fuck me over by losing their job or this time getting a no contact. I'm working on going sober now. Though today I took 3 grams of gabapentin. Not the worst drug to relapse on but still not good. I got a job lined up. It really does do me good to have so many people rooting for me. Thankyou. I used to envision hobos (nevrons) when I hear the word homeless. It feels good to know that others don't think that of me. Even known I'm posting in a forum about drugs and mixing substances and being homeless. It really does help to know there's open minds out there. I start work on wednesday. I'm really working on going sober. I haven't touched methadone or oxy or xans for a week now and I plan to keep it going. I blacked out on my birthday and woke up in the drunk tank covered in scrapes because I apparently jumped out a car on the freeway??? And assaulted hospital staff???? I dont remember any of it, but it fucked up my plea of abeyance involving my no contact charge with the girl that got me kicked out of our house. So that's it for me. I'm just laying my thoughts out at this point. Thankyou again. I'll get on top again, I won't let y'all down despite my name.

 

[IWantFentanylInMyShit]

lol…..ahhh, I’m sorry brother . I shouldn’t be advising people my 20+ years of tolerance to my legally scripted meds for chronic pain.

It really is a god send if needed, tolerance according

And yes….there are the standard low therapeutic doses for all substances

Perhaps I shouldn’t come on here after my Brompton Cocktail has reached its C-Max

My bad

You're good my guy, I've mixed a lot of things too. Usually just perc, xan, alcohol, and some non psychoactive things to make it better like muscle relaxers or whatever else. Maybe some lean if I can get my hands on it. Just make sure to give a disclaimer. It's useful to know that I can mix those things without worries of a seizure or something. Just keep that in mind

 

[IWantFentanylInMyShit]

You douchebag

Is this seriously the second time your first suggestion to a thread was a poly-substance drool fest. You're going from 0-60 a little too quick my friend.

@IWantFentanylInMyShit way to pick a name that speaks the truth of your heart.

Could you please tell us what specific side effects you're experiencing from the Methadone? That would help us narrow things down.

Promethazine (Phenergan) is a well-known and documented substance that is used frequently with Opioids for the subjectively "better" experience.

Ive gone in depth in other threads on this phenomenon. Sedative antihistamines, I believe, through their relatively minor sedative action on the nervous system, create a psychosomatic loop that makes us feel like we are higher.

Placebo is a relevant topic. If our bodies "feel high" our brains can relax and say "okay good, we're high".

That is my theory on the sedative antihistamines. They are great for relieving itch as well.

I'm just SUPER sensitive to ANY stimulant. I love psychedelics but they freak me the fuck out. Ketamine is my favorite substance EVER. Anyways, with that said- Oh wait, yeah I'm so sensitive to stimulants that if I drink a third of a monster at 4 pm, I'm not sleeping til 10 AM the next day. When I do adderall, 2.5 mgs gets me sweating and clenching. ANYWAYS, with that said. The serotonergic affects of methadone makes me "jerk" or spasm randomly, colors go brighter, light clenching, a faint nod off. Usually when I'm nodding off on percs or lean or 7 oh, I'm fent folding. Methadone feels like a very light nod off because the serotonergic anxiety keeps me jerking awake. Colors get brighter, I don't really have negative affects. I just feel the serotonergic effects. At least I'm pretty sure. I've done a lot of drugs and a lot of research to where I THINK (BIG emphasis on "think") That I'm attuned to know when my brain is releasing serotonin naturally during an activity or when a drug is serotonergic. An anecdotal testament I can make to that is feeling like 7 OH is serotonergic. There's very little research on it but some suggests that Kratom is indeed serotonergic. I think as we research 7 oh more, we'll learn that it's much more neurotoxic than we're lead to believe. When I do acid I feel like I'm over thinking and frying my brain but in hindsight, that stimulation seems like it's good for me, and that nodding off on 7 oh seems like that's actual brain fry. I tried an antidepressant once and that made me really dizzy and feeling like I was going to pass out. It was an SSRI so I don't know if I do understand serotonin as much as I thought. It didn't affect color at all or mood or anything, it just gave me tunnel vision and I felt I was gonna die, I did it right before work and had to go home, taking frequent stops while skating to bend my knees and lower my head to get my vision back before I passed out. All in all, methadone's more stimulative effects are pronounced with me, I get that weird thing that acid does where the outlines of objects are more defined and sometimes echo on themselves, I clench, colors get brighter, all that fun stuff without the spiritual awakening. I now understand that promethazine and methadone isn't a bad combo nor are gabapentanoids and methadone. I'm on 3.6 Grams of gabapentin right now. I prefer baclofen but fuck all that. I think I got what I needed out of this thread.

I fucked up on my birthday 6 days back and woke up in jail with 2 assault charges, one on a med staff public intoxication, and drug possession. I wasn't invited to my family's thanks giving because of it. It's NEVER good when I mix xannax and alcohol but that night sealed the deal for me. I'm NEVER mixing those two again. I wish I could just take them and be chill but no. I held a knife to this girl's throat??? I don't remember that whole night. I popped 6 xans, chugged some jager, teleported to feeding some puppies, I remember my friend taking her top off to show me some tattoos around her boobs, then I'm walking with police lights behind me and the cops are asking me if I knew I was on the side of the freeway, I had no idea what was going on or why I was missing 15 percent of my skin covered in scrapes. Then I woke up in the slammer not knowing what happened. I apparently jumped out a car going 80 mph because they were driving me to another friend's house because I woke up their roommate and got dragged out by my hair. All this shit. I'm done. I relapsed today on gabapentin and I don't want to do it again. Thankyou for your help. To anyone else reading this thread, here's what I found: The serotonergic effects of Methadone can mainly be dismissed, it's "okay" to mix it with other opioids and benzos if you "know what you're doing." I hope y'all do drugs for fun and not out of addiction. I'm gonna try to find sobriety, I haven't been who I wanted to be in 6 years now. Thanks for the help everyone.