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Lysergamides Lysergamide's L3A and L2A

Viraldrome

Bluelighter
Joined
Sep 26, 2018
Messages
356
I'm not a Chemist I was wondering if you could speculate on these substances, do you think they are active and should they be different than LSD? Its weird these are available and no one is talking bout them. According to people on reddit

LSD-25-Pyrrolidate (N-pyrrolidinyl Lysergamide)
Should by like LSM, that I'm not interested in but what about these L3A and L2A? Any speculation? I don't imagine you can just e mail Dr Nichols and ask him if he tried them. Do these sound promising?


L3A (N-3-amyl Lysergamide)​

MW: 487.553g/mol

MF:C21H27N3O.C4H6O6

L3A, N-3-pentyl lysergamide tartrate, (8β)-6-Methyl-N-(3-pentanyl)-9,10-didehydroergoline-8-carboxamide tartrate

Lysergic acid 3-pentyl amide (L3A, LSP) is an analogue of LSD with research conducted by; David E. Nichols at Purdue University and his team. It has similar binding affinity to LSD, with both 5-HT1A and 5-HT2A agonist properties & produces similar behavioral and physiological responses in animals with only slightly lower potency than LSD.


L2A (N-2-amyl Lysergamide)​


L2A (N-2-amyl Lysergamide) Tartrate Salt - 60mg or 60000µg



MW: 487.553g/mol

MF:C21H27N3O.C4H6O6

LSP, L2A, N-2-pentyl lysergamide tartrate, (8β)-6-Methyl-N-(2-pentanyl)-9,10-didehydroergoline-8-carboxamide tartrate

Lysergic acid 2-pentyl amide (L2A) is an analogue of LSD with research conducted by; David E. Nichols at Purdue University and his team. It has similar binding affinity to LSD, with both 5-HT1A and 5-HT2A agonist properties & produces similar behavioral and physiological responses in animals with similar potency than LSD. This is in racemic form and tartrate salt.



InChI=1/C21H27N3O.C4H6O6/c1-4-6-13(2)23-21(25)15-9-17-16-7-5-8-18-20(16)14(11-22-18)10-19(17)24(3)12-15;5-1(3(7)8)2(6)4(9)10/h5,7-9,11,13,15,19,22H,4,6,10,12H2,1-3H3,(H,23,25);1-2,5-6H,(H,7,8)(H,9,10)



Analogs of LSD Chart & In Vitro nM Binding Ki Values

LAMPA is also available, which i understand should be like MIPLA?
 
I have not tried any of these compounds and am mega curious about them as well.
LAMPA is also available, which i understand should be like MIPLA?
Maybe, probably, but who knows. Sounds like it might be less potent than MiPLA.

The #1 lysergamide I'm most curious about though is PRO-LAD, which I've never seen available. I wonder how much it's been tested out.
 
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