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What drugs just didn’t click for you?

Darvon also has a very narrow therapeutic window - so it's actually a quite dangerous drug!

For me:
DXM - felt bad and shaky (the sugars and the other shit in the cough syrup could've also contributed)
High dose cyclizine - no hallucinations
Risperidone, haloperidol - felt just BAD
Tramadol - where's the opioid euphoria? (worked as a fast-acting antidepressant though)

The idiot doctor i had at the time told me it was safer then codeine. This was before the internet really so i had no way to look it up. Really lucky i didnt mix t with alcohol
 
Pregabalin...... I found it incredibly uncomfortable. It was useful for opiate withdrawal but for getting high. I was confused and unable to understand how and why people find this stuff recreational.

2c-E people seemed to love, I just got a horrible body load.

DMT scared me shitless and I did not enjoy at all. I tried enough times to make a conclusion on this.

MDMA is ok, I don't dislike it. But compared to the rest of the world, I don't find it that great.
Growing up my friends took their required stash out and loved it, I rarely had one or 2. I was the outcast coz I liked acid which scared them to the point of not ever trying it. I was scared of MDMA not because of actual MDMA but because of getting something dangerous instead.
Until 25i nBOME came around that wasn't a worry with LSD and even then, "if it's bitter it's a spitter"
 
LSA i hated it so much fuck. The head space was so bad.

Dramamine. Enough said it was dramamine

DXM i just didnt like at all to fucking unpleasant

Tramadol is also just shit

Darvon was perhaps the worst drug i ever had besides dramamine though. Gave me nightmares and severe stomach pain
I used to get nightmares from darvon, too. Not that they ever stopped me from taking it.
 
I like MDMA, meth, heroin. In terms of effects, MDMA without tolerance is #1. Meth and heroin are a tie for #2. I don't take them anymore, but if offered, I'd definitely agree. Limited to at most a few times a year, those 3 are wonderful. In practice it's easier to avoid them entirely.
Do you still take any mdma or meth?
 
Pregabalin - doesn't do shit for me even at doses exceeding 3000mg. Its only effect is that I can't walk straight, feel completely sober otherwise.

a-PVP - no euphoria, but instant paranoia and unpleasant hallucinations which feel like 72h+ of sleep deprivation
 
Good question.

-Ketamine I can't stand-never again.
-2cb I don't like that much. Although I have had some good experiences overall my mind wanders too much I'm all over the place, there are better options.
-Some opiates make me nauseas
-High doses of acid-not fun. Low dose yes.
 
Weed, unfortunately. I did spend my youth smoking it but the paranoia and DPDR took over my life. I went in and out of transient psychosis states. Finally came to accept this fact. Still feeling like I'm missing out sometimes though, seeing how much enjoyment others get out of it.

Also, I never got the deal with clonazepam. I've enjoyed the other benzos I've tried, especially good ol' diazepam but clonazepam just felt like it drained the life out of me.
 
Weed, unfortunately. I did spend my youth smoking it but the paranoia and DPDR took over my life. I went in and out of transient psychosis states. Finally came to accept this fact. Still feeling like I'm missing out sometimes though, seeing how much enjoyment others get out of it.

Also, I never got the deal with clonazepam. I've enjoyed the other benzos I've tried, especially good ol' diazepam but clonazepam just felt like it drained the life out of me.

Nothing worse than weed that makes you paranoid.

Some strains I get paranoid and some I don't.
 
Nothing worse than weed that makes you paranoid.

Some strains I get paranoid and some I don't.
For real. Even crack, proper habitual use, didn't take my brain to those spaces.

Before I'd even tried other drugs, just smoking bud, i felt like my thoughts were beaming out from my head, people's words were distorting to spread my deepest secrets, all sorts of psychotic stuff. It has been said that I have a mild schizo-spectrum disorder but most substances don't trigger me that badly... except for when I had an n-bomb, rather absently-mindedly. The dude told me what it was and I'd heard of it and knew the risks but I'm an idiot and I'd been drinking. Now, that really did send me over the edge. Story for another time. I'm still processing that event. It freaked me the fuck out.
 
I seem to most relate to @ageingpartyfiend on this one - heroin and codeine both made me nauseous. Tried H about 5 times, all different batches from different plugs. So that's opiates right

I also do not enjoy painkillers. Vicodin, oxycodone, percocet.

Benzos I definitely feel the affect of, but it doesn't do anything very pleasure for me so I tend to take too many and black out.

Process of elimination - I must love stimulants?

Yeahh Sherlock Holmiess
 
-High doses of acid-not fun. Low dose yes.
Wow Im the absolute opposite regarding acid, low doses I get nauseous and not enough visuals nor euphoria, I just sit there holding my stomach while anxious trying not to throw up

High doses I puke and get it over with and then get blasted with euphoria. LSD always made me extremly nauseous for some reason, strange since I can tolerate 4-subbed trypts to 70mg and still manage to eat on them
 
We have all seen countless posts on countless forums and probably had countless conversations with people about which drugs are our favorites and why.

Ive always been fascinated by how varied peoples brain chemistry and enjoyment of certain substances can be, however Im curious about hearing the opposite and why? So tell me what are some drugs that DIDNT click with you despite all the hype and preach?
I have adhd and I think that is a bid reason I don’t like cocaine. It just makes me feel like I’m concentrating, like I took Ritalin or something. No euphoria and like antisocial.
 
I have adhd and I think that is a bid reason I don’t like cocaine. It just makes me feel like I’m concentrating, like I took Ritalin or something. No euphoria and like antisocial.
The pharmacological action of cocaine is very similar to ritalin, both NDRIs except cocaine has additional serotonergic activity

I always though coke was overrated and can be replicated or surpassed with other drugs
 
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