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What drugs just didn’t click for you?

Had a good strong trip on magic mushrooms and never again. Didn't find any lasting benefits either, but that's just me...

Side note, did 5 drops of liquid "Acid" (or whatever chem it was), and had such a life-changing trip I forgot I was even addicted to heroin it was incredible. Was a positive experience and I think there were long-lasting benefits...
 
Opioids and stimulants.
Same. Opioids made me feel like I want to puke the whole ride and cocaine, dexedrine and even mdma made me sketch out. Only good stim is Mate De Coca tea, 10 bags worth or coca leaves with a pinch of baking soda. That stuff is great. Give me a good buzz, wet clammy hands and make me want to poop right away as it kicks in.
 
Same. Opioids made me feel like I want to puke the whole ride and cocaine, dexedrine and even mdma made me sketch out. Only good stim is Mate De Coca tea, 10 bags worth or coca leaves with a pinch of baking soda. That stuff is great. Give me a good buzz, wet clammy hands and make me want to poop right away as it kicks in.
Ugh, I can’t stand the opioid high. They worsen my OCD, I find it nearly impossible to sleep on them, the itching drives me insane, and the nausea is brutal. They just don’t click for me, and I honestly wonder why. Every now and then I’ll take around 20–30mg of O-DSMT just to remind myself why I don’t like opioids, lol.

As for stimulants, cocaine is lackluster unless it’s smoked. Intranasal use either did nothing for me or made me feel like I was having a heart attack. D-amphetamine, Adderall, methamphetamine, etc are only tolerable for me at doses under 5mg. Anything more than that isn’t fun or productive. Maybe it feels okay for an hour, but then I just want it to end. I’ve always been extremely sensitive to stimulants. Until about eight months ago, I couldn’t even handle caffeine.

MDMA and MDA, though, are a completely different story. That stuff is the bee’s knees. I really wish you could safely take it once or twice a month because it’s fucking magical.

I will say that 4F-MPH is alright. I’ve only got ~500mg left, which is a shame since it’s practically extinct now, but it works well as an occasional booster. There are very few drugs I actually enjoy getting high on, and stimulants definitely aren’t one of them. I like taking a few milligrams orally. There is practically zero euphoria and no comedown, which is perfect for me.
 
Methamphetamine has consistently failed to register much in the way of positive or enjoyable effects.

I only started personally encountering MA within the last decade. I can't recall much of my first experience(s), but given my disposition at the time of regular use of IV heroin + IV cocaine [and IV use generally], I reckon I went right for a shot of some unknown dosage. I would later shoot (ha ha) for 0.10g-0.15g at a time - nothing too heroic, but as a novel user of amphetamines thought that it would be enough.

Never got much out of it, as it turned out. And missing any fraction of a shot was particularly miserable as far as that goes. Something about that agonizing burning sharp pain that suggests "no, don't."

I quickly stopped bothering with glass in general but in particular via IV. I'd later return for bouts on occasion but by smoking it, railing it, or encapsulating and ingesting it. Most of these bouts inevitably lead to some degree of profound regret for having gone on them. Paranoia/petite psychoses run amok and supreme.

Oral consumption seemed the most enjoyable RoA - and perhaps not coincidentally, it felt the most balanced. But ultimately the MA effects themselves amount to too much of a physical agitation state yet lack of a true bliss feeling to make the former worthwhile, and pretty much invariably lead to a dark mindspace at best - or a thoroughly deluded one at worst.

Bizarrely, boredom and various other highly modern afflictions still sometimes lead me to re-engaging with methamphetamine, typically smoked. But in general, it remains a rarity - just never clicked. So far, I have gone 2025 without it.
 
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