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Miscellaneous What Psychedelics Do You All Wish Were More Accessible?

I've never had pure mescaline, but I've had some great cacti which hold their own against any other phenethylamine I've had, which covers a lot of the 2C-X. I'm interested in trying MAL and/or AL, but I seriously doubt any of these would come close to substituting for mescaline, even the "inferior" plant-sourced variety.

2C-P, 25P-NBOMe

I don't think I'm even aware of a human report on 25P-NBOMe. Have you had it? And is it actually much like 2C-P?

If you like introspection from psychedelics, 2C-P is your material. most intense introspection I have ever experienced from any psych and even on low doses

I am about to try 2C-P for the first time sometime in the next month or two. I will probably start with only 1 mg. I used to like 2C-E a lot and probably still do, but my recent trips have been complicated by health factors. I hope it works out for me.
 
I've really been missing 2C-E lately. 2C-I and 2CT2 I really wish I could acquire. Never got to try 2C-P, 2CT4, 2CT21 or 2CT7 and would absolutely love the chance. I'm also very curious about HOT-2 and would be very interested in the Aleph series and Ganesha
 
It's quite curious. Shulgin postulates that the HOTs are very similar to the 2C-Ts due to being prodrugs. But there is the report of N-Hydroxy-2C-E (HOE :LOL:) somewhere in his notes (not PiHKAL) which does not seem to fit in with 2C-E.
 
How does it compare to 2cb in terms of tactile effects?
10 mg 2C-B ime was tactile, 10 mg 5-Meo-DIPT or somewhat more.
And its akin to a mix of LSD/ faint Tryptamine effects/ the pitch effect on sound.
And a dose of Speed on top.

So to me, it seems as tactile as LSD not like 2C-B, which is akin more to MDMA.
And was actually sold in sex-shop s [NEXUS].
FOXY as nickname for, 5-Meo-DIPT. Wonder if that is ment as giving a glimp of supposed erotic effect s. Or other ?

Ime had none on Foxy, They also wrote it was MDMA like, didn t seem so at all !
So the term could just point to its surprising heavy & fast hitting trip.
 
The 3,4- double substituted 2C-Xs and DOXs
Stuff like 2C-G, Ganesha, DODC

all other dialkyl and dihalogen substitutions
Unexplored combinations with different alkyls and halogens being swapped around in the 3rd and 4th position

The possibilities are vast
Only one ive seen returning lately is 2C-G-5
 
The antihistamine Chlorpheniramine is a mild psychedelic, and I know a lot of people don't agree on this, but Chlorpheniramine's structure is so close to Tryptamines.

It has has potent antihistamine, but weak deliriant effects which can make it less psychedelic. It definitely has psychedelic potential, and synergizes well with psychedelics in my opinion.

It's also very dangerous when abused.
 
The antihistamine Chlorpheniramine is a mild psychedelic, and I know a lot of people don't agree on this, but Chlorpheniramine's structure is so close to Tryptamines.
Close to tryptamines how? Chlorpheniramine has a phenyl and pyridine ring it looks nothing like a tryptamine
Its not even a 5ht2a agonist…
 
Colour is already fairly accessible. I tried sending you a private message but you have your account security settings ratcheted way up evidently…

There's also 'Comet', aka 4-AcO-MET (get it? aka: 'Azomet', aka: 'Metacetin'), and that's a prodrug to Colour (4-HO-MET, aka: 'Metocin') and the end result is damn near the same thing. Either way, yes, I very much ❤️ this particular substance, good choice. Another worthwhile and similar compound is: 4-HO-MiPT, aka: 'Miprocin'. Btw, I like your username; made me lol 🙂

Close to tryptamines how? Chlorpheniramine has a phenyl and pyridine ring it looks nothing like a tryptamine
Its not even a 5ht2a agonist…
Actually I believe it does have affinity for the serotonin subtypes 5-HT2A and 5-HT2C. Check out the pharmacodynamics listed on Wikipedia. However, I will agree with you that it is not structurally similar to tryptamines, which feature an indole scaffold + an ethylamine side arm. My first impression is that it looks like an anticholinergic drug similar to the arylcyclohexylamines, but w/two phenyls. Primarily it affects histamine, but secondarily it affects serotonin, whilst weakly affecting dopamine and norepinephrine. And sure enough, it's anticholinergic, too. What a weird compound. Thanks for pointing it out, @The Holy Quadruplty

Darrel Lemaire sure made the Tweetio series sound fun on Hamilton's Pharmacopeia… Also, despite the purported cardio problems that can develop, I would like to dabble some with 4-methylaminorex (aka: 4-MAR, 4-MAX, Euphoria, U4Euh (I'm cringing just writing that), &c.)… and yes, I know there are analogs on the RC market, but it's not the same. Also, if you research it, you'll find that the trans enantiomer, trans-4-methylaminorex, is oddly and specifically not scheduled, only cis-4-methylaminorex. Supposedly the feds thought the trans enantiomer was inactive, but it turns out it's more active than the cis enantiomer. Here's more on the subject archived on the Erowid from Rhodium's old site.

I wish someone would whip up a large RC batch of the trans enantiomer via—if memory serves—potassium cyanate and phenylpropanolamine.HCl (aka: norephedrine hydrochloride). Much safer than making the cis enantiomer from cyanogen bromide which is both deadly poisonous and volatile to boot. No thank you. Blast shield chemistry is pretty hardcore, all things considered. All this was figured out on the Hive circa 2003. Then there's a 2004 federal case in the southern district of Florida, United States of America v William Hahne worth checking out. It established that the 1985 Analog Act didn't apply to trans-4-MAR due to the fact that enantiomers ≠ isomer analogs. Bill still got 48 months for the cis portion the DEA busted him with, and later, after his release, he was arrested again for mailing NBOMe psychedelics to a few of his inmate homies still in the joint. Oops. Bill has good ideas, but poor execution it seems.

Too bad 4-MAR purportedly causes COPD and other cardiotoxic shenanigans. No bueno.

EDIT: Also, I understand 3,4-methylenedioxy-aminorex is active and excellent… there's also a 2C-B-Aminorex that I'm curious about.
 
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Colour is already fairly accessible. I tried sending you a private message but you have your account security settings ratcheted way up evidently…

There's also 'Comet', aka 4-AcO-MET (get it? aka: 'Azomet', aka: 'Metacetin'), and that's a prodrug to Colour (4-HO-MET, aka: 'Metocin') and the end result is damn near the same thing. Either way, yes, I very much ❤️ this particular substance, good choice. Another worthwhile and similar compound is: 4-HO-MiPT, aka: 'Miprocin'. Btw, I like your username; made me lol 🙂


Actually I believe it does have affinity for the serotonin subtypes 5-HT2A and 5-HT2C. Check out the pharmacodynamics listed on Wikipedia. However, I will agree with you that it is not structurally similar to tryptamines, which feature an indole scaffold + an ethylamine side arm. My first impression is that it looks like an anticholinergic drug similar to the arylcyclohexylamines, but w/two phenyls. Primarily it affects histamine, but secondarily it affects serotonin, whilst weakly affecting dopamine and norepinephrine. And sure enough, it's anticholinergic, too. What a weird compound. Thanks for pointing it out, @The Holy Quadruplty

Darrel Lemaire sure made the Tweetio series sound fun on Hamilton's Pharmacopeia… Also, despite the purported cardio problems that can develop, I would like to dabble some with 4-methylaminorex (aka: 4-MAR, 4-MAX, Euphoria, U4Euh (I'm cringing just writing that), &c.)… and yes, I know there are analogs on the RC market, but it's not the same. Also, if you research it, you'll find that the trans enantiomer, trans-4-methylaminorex, is oddly and specifically not scheduled, only cis-4-methylaminorex. Supposedly the feds thought the trans enantiomer was inactive, but it turns out it's more active than the cis enantiomer. Here's more on the subject archived on the Erowid from Rhodium's old site.

I wish someone would whip up a large RC batch of the trans enantiomer via—if memory serves—potassium cyanate and phenylpropanolamine.HCl (aka: norephedrine hydrochloride). Much safer than making the cis enantiomer from cyanogen bromide which is both deadly poisonous and volatile to boot. No thank you. Blast shield chemistry is pretty hardcore, all things considered. All this was figured out on the Hive circa 2003. Then there's a 2004 federal case in the southern district of Florida, United States of America v William Hahne worth checking out. It established that the 1985 Analog Act didn't apply to trans-4-MAR due to the fact that enantiomers ≠ isomer analogs. Bill still got 48 months for the cis portion the DEA busted him with, and later, after his release, he was arrested again for mailing NBOMe psychedelics to a few of his inmate homies still in the joint. Oops. Bill has good ideas, but poor execution it seems.

Too bad 4-MAR purportedly causes COPD and other cardiotoxic shenanigans. No bueno.

EDIT: Also, I understand 3,4-methylenedioxy-aminorex is active and excellent… there's also a 2C-B-Aminorex that I'm curious about.
I really HATE 4-AcO-DMT & had one of the worst trips from it ever, I rate it equal to 3C-E ( 3,5-dimethoxy-4-ethoxyphenethylamine)
 
Actually I believe it does have affinity for the serotonin subtypes 5-HT2A and 5-HT2C. Check out the pharmacodynamics listed on Wikipedia. However, I will agree with you that it is not structurally similar to tryptamines, which feature an indole scaffold + an ethylamine side arm. My first impression is that it looks like an anticholinergic drug similar to the arylcyclohexylamines, but w/two phenyls. Primarily it affects histamine, but secondarily it affects serotonin, whilst weakly affecting dopamine and norepinephrine. And sure enough, it's anticholinergic, too. What a weird compound. Thanks for pointing it out, @The Holy Quadruplty
Well yes I admit it does posses some serotonergic activity like a lot of the first gen antihistamines do but its 5HT2A and 5HT2C activity is essentially negligible
 
I really HATE 4-AcO-DMT & had one of the worst trips from it ever,
Wait so you're saying you like 4-HO-MET but hate 4-AcO-MET? Personally, I can't reliably tell them apart or from placebo. And it's believed that the same way psilacetin is a prodrug to psilocin, so too Comet would be a pro-drug to Colour.

I rate it equal to 3C-E ( 3,5-dimethoxy-4-ethoxyphenethylamine)
Almost… slight correction:
☞ 3C-E = 3,5-dimethoxy-4-ethoxyamphetamine
Escaline
= 3,5-dimethoxy-4-ethoxyphenethylamine

Remember:
2C-x drugs are phenethylamines, none of which are alpha-methylated
3C-x drugs are amphetamines, which stands for "alpha methyl phenyl ethyl amines"

nmaouvd.jpeg


Meanwhile 3C-x drugs are the amphetamine equivalents of the 2C-x analogs.

0bQsYEx.jpeg


I wasn't very consistent in portraying these, but just know: everywhere two straight lines converge, there is a carbon atom there and its open valence shells are being filled with electrons donated from hydrogen atoms. Depicting this would be tedious, so chemists use this as a shorthand, if you will… Anyways, I hope this helped someone learn, or understand, something new. If not, sorry about the ramble, peoples!
 
First thought so far nothing to complain. Lysergics and Tryptamine s are save.
For the time being. :unsure:

But there are more people around who never had access to:
g/ ch-ems like 2C-B and 2C-T2.
So with all Phenethylamines banned, though they ment to hit,
Amphetamines/ Cathinone s and Emphatogen s.

So bring back 2-C s [exclude the ones that are dangerous. Governments can do as they please so customise to the peoples need s, i d say]. Same goes for the DOxx series to i guess [imo they stay illegal, but it s not about me/ bring in the expert s]. Mescaline analogue s [Mescaline you can extract, but they can legalise that too imo].
The TMA s am i missing someone ?

Couple that with the fact all the analogues of LSD are legal,
yet LSD is not. Not FAIR :mad:This has to end, reinstall it s legendary status.
Make a statue for A. Hoffman to make up !
 
Mxe it’s the only drug I want to try still
Are Dissociative s Psychedelic, it s a opinion based on my experience.
But i never got the exact same feel on them, i don t take em anymore.
As i discovered except N2O and Ketamine. Had soft spot for MXE,
which is stimulating. And very functional dosed low with tolerance.

The hole, which i experienced lucid as no amount put s me out.
Was out of this world, alien. Yet fully conscious sort of.
"Shit no bike lights and it s getting dark, why is it getting dark ?
But if a Cop spot me. 'What the f... is that a Lunar launch platform,
with light s & so,why are there no people ?" ..

Oh Cop s, a fine of 150 euro. So got of my bike and walked back home.
Lucky MXE is not prone to mania that would have been disaster es.
Didn t know most disso s can lead to mania, why i banned them.
K is most benign so at least it seems but the bladder problems i find worrying.

And sadly the average human need s to be protected from him/ herself.
Harm-reduction goes only so far <---------------------------------------------->
 
Despite people often saying that, nobody I've ever seen use it in person has ever had a bad time, just anecdotally at least.


How would you compare Moxy to Foxy? And have you considered self supplying your DMT via plant extractions?
My 2 ct. taking both and 4-ho-MIPT, which to me seemed like the gentler of the 2.
Even 5-Meo/ 4-ho-MET had more body load. To me its the Gem of the 3,

Maybe like someone compared DIPT as the supriour version,
compared with 5-Meo-DIPT. Which is very unselective.
Like taking 3 drugs at once, a Tryptamine and some LSD and Speed.

So i am very curious about MIPT. But 5-Meo-DIPT I have still laying around.
My first RC, discounting GHB. Can you convert it to MIPT.
Shut up 🤐 no synthesis discussion !
 
May sound weird but I really wish i could get DXM lol.
In my country its not avaiable over the counter.
And even if I had a bad cough i doubt i could get enough from the doctor for a strong trip.

High dose DXM is one of my favorite experiences.
Its just such a weird and overwhelming trip.
 
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