Opioids DHC long term use

[xyZedd]

Hi all, can anyone comment on the long term effects of DHC consumption? eg at levels of around 180mg per day for several years, how badly will it screw up your liver, etc?!

 

[lost weekend]

Hi I took 30mg dhc for 2 years solid but I also drunk and when I went to the doctor the results were I had a fatty liver.i lied of course and said I rarely drink but eat lots of sugery foods and drinks.it was probably just the alcohol that caused it .I used to mix and match administration, oral and the other way .I'm no expert but I think rectel administration bypasses most of the drug from the liver ,but someone else on the forum will be able to tell you for sure

 

[lost weekend]

Sorry when I say 30mg I mean that was the tablets not the dose I was taking ,I'd sometimes take 150mg one way and swallow 150mg in the same dose

 

[xyZedd]

Hi I took 30mg dhc for 2 years solid but I also drunk and when I went to the doctor the results were I had a fatty liver.i lied of course and said I rarely drink but eat lots of sugery foods and drinks.it was probably just the alcohol that caused it .I used to mix and match administration, oral and the other way .I'm no expert but I think rectel administration bypasses most of the drug from the liver ,but someone else on the forum will be able to tell you for sure

I just replied to you on the other thread haha, thanks I think you are on the right track re plugging. Will do a bit of research and plan to phase over into that method of admin

 

[lost weekend]

I just replied to you on the other thread haha, thanks I think you are on the right track re plugging. Will do a bit of research and plan to phase over into that method of admin

Yeh everyone is different when it comes to plugging ,I used more water than most it seems,some people use 5ml I used at least 10 to 15ml especially if your crushing alot of pills ,I used to get them crushed really fine like powder and some warm water .I soon realised i needed less pills for same effect if swallowed but it is harder hitting and seems to last longer .like you say research is the best way to go .

 

[lost weekend]

A mixture of the 2 seemed to work for me with less orally

 

[KurtAurelius]

There’s a thread I can’t remeber where but it’s called something like “long term effects of opioids”

But generally speaking from my knowledge it’s receptor down regulation leading to tolerance and dependence, suppressed hormones and worsening ability to handle pain.

Then certain opioids have specific issues to their pharmacology like Tramadol, Tapentadol, Pethedine, Darvocet(can’t spell the chemical name) Dextromethadone etc but this is due to seperate issues not pure opioid activity.

This thread is questioning the validity of “opioids are basically inert otherwise” but so far I’ve not seen much other notable issues, but you should read the thread for yourself.

One could say it’s either having to accept coming off and needing a long period to recover your natural homeostasis, or to keep taking Opioids.

It’s not my call to say which is which, but I’d personally say they should only be used sparingly and if needed 24/7, only for pain that is not managed otherwise.

 

[lost weekend]

There’s a thread I can’t remeber where but it’s called something like “long term effects of opioids”

But generally speaking from my knowledge it’s receptor down regulation leading to tolerance and dependence, suppressed hormones and worsening ability to handle pain.

Then certain opioids have specific issues to their pharmacology like Tramadol, Tapentadol, Pethedine, Darvocet(can’t spell the chemical name) Dextromethadone etc but this is due to seperate issues not pure opioid activity.

This thread is questioning the validity of “opioids are basically inert otherwise” but so far I’ve not seen much other notable issues, but you should read the thread for yourself.

One could say it’s either having to accept coming off and needing a long period to recover your natural homeostasis, or to keep taking Opioids.

It’s not my call to say which is which, but I’d personally say they should only be used sparingly and if needed 24/7, only for pain that is not managed otherwise.

Yeh your right.opiate prescription drugs like dhc and codeine help with minor pain but in my experience after the worst of pain is gone otc medicine should be sufficient.i know there's people who live in terrible pain and it's a god send these types of opiates are available to them .