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Opioids kratom tolerance?

vlzinspace

Bluelighter
Joined
Dec 16, 2022
Messages
250
i found green bali kratom in my stash and took about 12g on an empty stomach. never took it before... the euphoria is surprising, feels like a 10mg oxycodone lol. feelin gooood

does tolerance work like regular opiates or does it build fast with kratom?
 
Hey @vlzinspace

There are a lot of people on these forums who are heavily addicted to Kratom and Kratom-analogous compounds right now like 7-Hydroxymitragynine/7OH. The primary compound of note in Kratom is known as Mitragynine. It functions similarly to other Opioid agonists. It doesn't seem to follow any truly different/complex rules regarding its pharmacokinetics like you would say Buprenorphine (Suboxone) does.

Kratom has occupied a vacuum that was created by a lack of moderate-potency Opioids available to street/recreational/self-medicating users. The "Opioid Epidemic" in the sense of the whole "Oxycontin/Purdue" scandal led to a massive inundation of the street market with cheap, available Opioids. At that time, Oxycodone would have been considered a "high" potency Opioid, though with Fentanyl on the street as it is now, I feel it's more appropriate to call Oxycodone "moderate".

There are people with jobs, families and lives who can't afford to be seen using something like Fentanyl. It's not a drug that lends itself to stability. Now, all of the folks who used to buy these pills on the street have little else but these Kratom products. Your experience and your description of dosage is pretty similar to others that we've discussed here on the forums.

It does produce tolerance, withdrawal... all of that stuff. I am friends with a guy on here who was taking scoops of Kratom powder ever 2-3 hours for almost 10 years if that helps put things in perspective. He said it was the most addictive substance he had ever experienced, but this is just one report.
 
I’ve found kratom horribly addicting. Tolerance builds fast, and withdrawal is a bitch. Also, that. High you get pretty much evaporates after a few weeks. It’s pretty much like other opiates, though withdrawal from heroin was worse as far as gastrointestinal symptoms are concerned. I agree that for most of us, kratom is pretty much all there is besides dangerous street fentanyl, which most sane people know better than to touch. I don’t think oxycodone or hydrocodone are any better though. I miss good quality heroin, but it’s become something most mere mortals will never taste. Not that being addicted to dope is any better, but the high sure is.
 
awesome insight my dudes i appreciate it. i've come to love it for the simple fact i can get my opioid taste in without going on a heroin binge, paying insane amounts for legit pills or just the risk in general from naive tolerance. seems like it'd be great to do on the weekend with some ganja.

is there a great difference in strain? i hear white maeng da is really good/euphoric
 
I’ve found kratom horribly addicting. Tolerance builds fast, and withdrawal is a bitch. Also, that. High you get pretty much evaporates after a few weeks. It’s pretty much like other opiates, though withdrawal from heroin was worse as far as gastrointestinal symptoms are concerned. I agree that for most of us, kratom is pretty much all there is besides dangerous street fentanyl, which most sane people know better than to touch. I don’t think oxycodone or hydrocodone are any better though. I miss good quality heroin, but it’s become something most mere mortals will never taste. Not that being addicted to dope is any better, but the high sure is.
Why ? But my experience the opposite. Never noticed tolerance forming,
after the initial period i stabilised at +/-15 gram/ day [5 x 3 gr].
But that equal s 30 to 50 gr. From local vendor s,
direct from the source was twice as strong.

And after x period taking it, i got tired depressed, the cue to taper.
Stop a while and restart, and it would function again as i liked:
energizing, mood enhancing and promoted good sleep.
And it was dirt cheap. The addiction was imo peanuts,
But GHB/ GBL i feel the same about, easy.
Only Alcohol addiction was ime disastrous.

3 weeks WD, and then PAWS. Thats hard compared to 3 day s for GHB,
or the 5 involved quitting Kratom [Leaf powder]. But YMMV !
But considering of the 3 Alcohol was the least pleasant drug.
 
I think it’s the fact that I’ve been using kratom for at least 15 years might have something to do with it. Also, I already had a decade plus opiate habit before that. Each time I’ve quit, the withdrawals were worse. Kratom barely scratches that opiate itch for me, but it keeps me from drinking excessively, or toying with the idea of banging some fentanyl.
I used gbl for 10 years daily, and when it ran out, no withdrawals at all.
I’ve never had alcohol, withdrawals, though I’ve had long stretches of heavy drinking. I don’t drink anymore. Alcohol is poison for me.
 
i found green bali kratom in my stash and took about 12g on an empty stomach. never took it before... the euphoria is surprising, feels like a 10mg oxycodone lol. feelin gooood

does tolerance work like regular opiates or does it build fast with kratom?
It can escalate very fast if you let it but then it also drops very fast. In terms of strains after taking kratom on and off for 8 years im still not sure lol. Theirs so many variables that effect kratoms potency like, hydration levels, how well slept you are, how old the kratom powder is/how it was stored, digestive health.

Tbh I wouldn't mess with it its just not worth the risk. Some people make light of it because its weaker then traditional opiates but personally at this point I have such an affinity for it id take it over any other drug ive tried. It can hook you really bad and when it gets you the high lasts about an hour and a half and then you feel like garbage the rest of the time.
 
Slightly on and off topic but as most know I have tried kratom from white, green and red and all different strains and all did f'all for me but then I came across. MIT aka mitragynine pure extract in 40mg tabs and about 5 of those actually made a dent and a bit one.

Don't even wanna think of the new extracts. Be carefull people this is at the end of the day an opioid... and addiction will develop, so be careful and reasonable with your dosing. But if you just wanna get high then you in the wrong place.

FYI: not directed at OP. Just a general statement
 
i understand completely, i do only want the high (i found the stimulation surprisingly useful also) but i want to stay far away from actual opiates. it's a nice inbetween but to the naive mind it can definitely sweep them away, its basically an opiate... mitragynine or whatever actual compound but serves as essentially the same thing
 
The brand "Opia" is the best quality 7-OH sold in head shops/smoke shops. It is the only brand I will buy. It is best used for the 1st opioid dose of the day as it loses it punch if taken all day long.

If I had to switch from my daily Roxicodone and Methadone dependence to 7-OH, I would be extremely broke and have increased pain. It is too overpriced for me even buying it by the case (10qty).

I take the 7-OH 2-3 times a month in the 120mg-180mg dosage range in one sitting to achieve the feeling I am after. It does make for a pleasant 2-3hr experience.

Taking both 7-OH & normal Kratom powder capsules is the best way to take it.

There is a MOD here on the forum that buys the 7-OH online that comes in a crystalized powder. He says it is the best way to indulge.
 
The brand "Opia" is the best quality 7-OH sold in head shops/smoke shops. It is the only brand I will buy.
Agreed, although some other brands are OK too. Most are jank and way underdosed. Opia is good. This website is good: https://www.testmykratom.org/brands

But as far as quality and dose per price from vape shops, Opia is one of the best


It is too overpriced for me even buying it by the case (10qty).
There is a MOD here on the forum that buys the 7-OH online that comes in a crystalized powder. He says it is the best way to indulge.

It's a lot cheaper if you just buy 7oh powder instead of branded pills

I only buy the pills from vape stores if I'm in between powder 7oh shipments, it's a lot more expensive.

Taking both 7-OH & normal Kratom powder capsules is the best way to take it.
Agreed. Kratom alkaloids have an "entourage effect" just like cannabis. 7oh is more euphoric if paired with other kratom alkaloids. It also cuts down on how much 7oh you need. It's the best way to take it for sure.
 
i understand completely, i do only want the high (i found the stimulation surprisingly useful also) but i want to stay far away from actual opiates. it's a nice inbetween but to the naive mind it can definitely sweep them away, its basically an opiate... mitragynine or whatever actual compound but serves as essentially the same thing
Its really not an inbetween tbh once you let your doses get high. I loved tramadol aswell and a high dose of kratomw hile,hydrated on an empty stomach feels just like a high dose of that. It might not be heroin or some of the harsher opiates but it for sure gives a good buzz. I think the reason we have so many people discounting it as a real opiate is
1- They stick to very low doses
2- Kratom is fickle because you are digesting a bunch of plant matter so it doesnt digest and enter your blood stream as quick as a pill designed to do so. Empty stomach and hydration is required for good effects.
 
Hey @vlzinspace

There are a lot of people on these forums who are heavily addicted to Kratom and Kratom-analogous compounds right now like 7-Hydroxymitragynine/7OH. The primary compound of note in Kratom is known as Mitragynine. It functions similarly to other Opioid agonists. It doesn't seem to follow any truly different/complex rules regarding its pharmacokinetics like you would say Buprenorphine (Suboxone) does.

Kratom has occupied a vacuum that was created by a lack of moderate-potency Opioids available to street/recreational/self-medicating users. The "Opioid Epidemic" in the sense of the whole "Oxycontin/Purdue" scandal led to a massive inundation of the street market with cheap, available Opioids. At that time, Oxycodone would have been considered a "high" potency Opioid, though with Fentanyl on the street as it is now, I feel it's more appropriate to call Oxycodone "moderate".

There are people with jobs, families and lives who can't afford to be seen using something like Fentanyl. It's not a drug that lends itself to stability. Now, all of the folks who used to buy these pills on the street have little else but these Kratom products. Your experience and your description of dosage is pretty similar to others that we've discussed here on the forums.

It does produce tolerance, withdrawal... all of that stuff. I am friends with a guy on here who was taking scoops of Kratom powder ever 2-3 hours for almost 10 years if that helps put things in perspective. He said it was the most addictive substance he had ever experienced, but this is just one report.
Wow! This is very informative. I’m amazed that I haven’t heard of Kratom until now? I feel like Patrick Star from Sponge Bob square pants that lives under a Huge Rock! Lol 😂
 
Yeah, those initial times with kratom are like WOW HOW CAN THIS BE LEGAL, but any chasing of that initial feeling will give vastly diminishing returns unless you put lots of time in between uses. It can be very useful for those with a strong constitution that can put shit aside when they need to, but there is no denying how compulsive it can be.
 
Yeah, the diminishing returns seem like utter bullshit with kratom. This last time I would say that being high was a lot worse than being sober, and all I have ever done with it is chip it.
But I certainly enjoyed it in the early days.
 
Copying this from a post I made on another kratom thread...

BTW adding the cheap OTC supplement agmatine will help.
Agmatine reduces withdrawl symptoms, reduces the build-up of tolerances and potentiates the effects of most drugs, especially opioids, benzos and cannabinoids.
I've written a lot about agmatine in my other posts.

I think 100g agmatine powder is $17. In Britain 250g agmatine is £17. Buying it in capsules is probably more expensive.

If you can't get ibogaine (a serious anti-addiction aid) then agmatine is the next best thing.

The major constituent, mitragynine, is also a proposed agonist at the adrenergic alpha-2 receptor, a mechanism that is currently utilized in opioid withdrawal therapies with mechanism of action similar to clonidine, a selective alpha-2 receptor agonist.
Agmatine is also an alpha-2 receptor agonist (and NMDA antagonist).

As for potentiation...all OTC and cheap...
- Myrhh (oil or CO2 extract, in capsules ofc)
- curcumin
- Eugenol (opioid, glutamate antagonist)
- Opioid terpenes
- CBG (potent alpha-2 adrenergic agonist)
- Hordenine (dopamine D2 agonist, NRI stimulant, temporary MAO-Bi)
- Theacrine (caffeine-related stimulant)
- Theanine (sedative)


PS. Kratom is more than just an opioid. Also cannabinoid, adrenergic, dopaminergic, serotonergic.
Mitragynine works through cannabinoid receptors +
Mitragynine possesses a non-opioid action through alpha-2 adrenergic, adenosine (A2A), dopamine (D2), and serotonin (5-HT2A, 5-HT2C, 5-HT7) receptors.
 
Last edited:
Copying this from a post I made on another kratom thread...

BTW adding the cheap OTC supplement agmatine will help.
Agmatine reduces withdrawl symptoms, reduces the build-up of tolerances and potentiates the effects of most drugs, especially opioids, benzos and cannabinoids.
I've written a lot about agmatine in my other posts.

I think 100g agmatine powder is $17. In Britain 250g agmatine is £17. Buying it in capsules is probably more expensive.

If you can't get ibogaine then agmatine is the next best thing.


Agmatine is also an alpha-2 receptor agonist (and NMDA antagonist).

As for potentiation...
- Myrhh (oil or CO2 extract, in capsules ofc)
- curcumin
- Eugenol (opioid, glutamate antagonist)
- Opioid terpenes
- CBG (potent alpha-2 adrenergic agonist)
- Hordenine (dopamine D2 agonoist, NRI stimulant, temporary MAO-Bi)
- Theacrine (caffeine-related stimulant)
- Theanine (sedative)
Brah brah.. thank you for the decent reply. 1st yeah I can get ibogaine on my ace but if I do go that route it would obviously be under a supervised Location or atmosphere with actual real doctors on stand by. But that's for me as a last type of way to get rod of my opioid addiction. Even though I have it under control meaning on a very low maintenance lvl dose of methadone, I would like to kick the habit and have that exp ( Wethersfield it's true or not ) but luke never have experienced opioids.
 
I haven’t found Kratom to be too addictive for me but I try green Vain Kratom powder. I don't do Kratom more than once or twice a week and usually take a month or more of breaks in between. Once in a while, I did Kratom shots or Kratom seltzer. But only yesterday, I found out about 7-OH or 7-OH-Mitragynine and they're already getting closer to banning it. Also, there was a guy in a video saying, "7-OH is dangerous and addictive".
 
The brand Opia starting putting out a 60mg tablet @ 240mg per pack.

The brand Roxy puts out a 60mg tablet @ 300mg per pack

The brand Blend puts out a 60mg tablet @ 240mg per pack.

Of the three I would pick Opia everytime. It has the most comparable feeling to standard opioids like Oxycodone mixed with Morphine.

The brands Roxy and Blend are still good picks.

I worked an edge on the smoke shop and I get a 15-20% discount. Those guys from Northern Africa and the Middle East understand haggling and will not turn away business.
 
The brand Opia starting putting out a 60mg tablet @ 240mg per pack.

The brand Roxy puts out a 60mg tablet @ 300mg per pack

The brand Blend puts out a 60mg tablet @ 240mg per pack.
That's insane dosages... this is why this shit is being banned and scheduled. If an opioid naive person took 60mg tablet that could land them in the freakin hospital man (not seriously, but it could, that's a huge fuckin dose)

This arms race from these companies is ridiculous and irresponsible. That and naming your shit "Roxy" or "Perks"... ffs man
 
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