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Mental Health Coming off Invega/Xeplion (paliperidone) injections v. 10

Been having a stiff few days, which sucks.

I have work tomorrow so I hope I am better at least a little bit by tomorrow.
 
Paliperidone is an active metabolite of risperidone is it not? I suggest it's popularity is because it's possible to produce a long-chain ester derivative (palminate) hence depot injections.

Has anyone ever been prescribed both risperidone and paliperidone and can they comment if the latter is the more objectionable i.e. does it produce more side-effects?

I have to say I am truly shocked that seemingly so many people are given depot injections of an antipsychotic. If the dose is too high, it cannot be adjusted until 28 days have elapsed. Do doctors inject the whole dose or if a patient suffers severe side-effects, do they inject less with a view to the patient recieving a lower dose of the active?

As a class of medication, antipsychotics just seem to be accepted by clinicians in spite of every one of the class prodcing terrible side-effects in a lot of patients.

BTW by 'recovery' do we mean that although the depot is supposed to last for 28 days, in fact it can take months or years for the drug to be completely removed from the body?
 
4DQSAR said:
Paliperidone is an active metabolite of risperidone is it not? I suggest it's popularity is because it's possible to produce a long-chain ester derivative (palminate) hence depot injections.

Has anyone ever been prescribed both risperidone and paliperidone and can they comment if the latter is the more objectionable i.e. does it produce more side-effects?

I have to say I am truly shocked that seemingly so many people are given depot injections of an antipsychotic. If the dose is too high, it cannot be adjusted until 28 days have elapsed. Do doctors inject the whole dose or if a patient suffers severe side-effects, do they inject less with a view to the patient recieving a lower dose of the active?

As a class of medication, antipsychotics just seem to be accepted by clinicians in spite of every one of the class prodcing terrible side-effects in a lot of patients.

BTW by 'recovery' do we mean that although the depot is supposed to last for 28 days, in fact it can take months or years for the drug to be completely removed from the body?
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It takes longer than 28 days for a single injection to leave the body. Took me 9 months to heal from 2
 
I went into psychosis again so now I’m stuck on a CTO. 6 injections of Abilify so far. It’s very similar to invega when it comes to side effects for me
 
4DQSAR said:
Paliperidone is an active metabolite of risperidone is it not? I suggest it's popularity is because it's possible to produce a long-chain ester derivative (palminate) hence depot injections.

Has anyone ever been prescribed both risperidone and paliperidone and can they comment if the latter is the more objectionable i.e. does it produce more side-effects?

I have to say I am truly shocked that seemingly so many people are given depot injections of an antipsychotic. If the dose is too high, it cannot be adjusted until 28 days have elapsed. Do doctors inject the whole dose or if a patient suffers severe side-effects, do they inject less with a view to the patient recieving a lower dose of the active?

As a class of medication, antipsychotics just seem to be accepted by clinicians in spite of every one of the class prodcing terrible side-effects in a lot of patients.

BTW by 'recovery' do we mean that although the depot is supposed to last for 28 days, in fact it can take months or years for the drug to be completely removed from the body?
Click to expand...
I’ve been on risperidone pills before as well as Paliperidone injections. Both turned me into a zombie. Both terrible
 
4DQSAR said:
Paliperidone is an active metabolite of risperidone is it not? I suggest it's popularity is because it's possible to produce a long-chain ester derivative (palminate) hence depot injections.

Has anyone ever been prescribed both risperidone and paliperidone and can they comment if the latter is the more objectionable i.e. does it produce more side-effects?

I have to say I am truly shocked that seemingly so many people are given depot injections of an antipsychotic. If the dose is too high, it cannot be adjusted until 28 days have elapsed. Do doctors inject the whole dose or if a patient suffers severe side-effects, do they inject less with a view to the patient recieving a lower dose of the active?

As a class of medication, antipsychotics just seem to be accepted by clinicians in spite of every one of the class prodcing terrible side-effects in a lot of patients.

BTW by 'recovery' do we mean that although the depot is supposed to last for 28 days, in fact it can take months or years for the drug to be completely removed from the body?
Click to expand...
I found risperidone and paliperidone to be very similar. It was a while ago, I think the latter felt a bit cleaner. Hard to remember.

They stabilize you on pills before they give the depot shots.

The side effects tend to reduce a lot after a few months.

It's not that the drug takes that long to clear the body, just it's impact on the brain lasts for a while.
 
Invegatorture said:
I took LSD
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damn If I recover from invega i'm never touching drugs ever again. Our brains are just not the same after psychosis and are much more sensitive so you gotta be extra careful doing any substances. Fortunately for you, you have recovered once before and your brain knows how to recover so it most likely will be the same with abilify. Hopefully your CTO ends soon 🙏
 
TonyTonyChopper said:
damn If I recover from invega i'm never touching drugs ever again. Our brains are just not the same after psychosis and are much more sensitive so you gotta be extra careful doing any substances. Fortunately for you, you have recovered once before and your brain knows how to recover so it most likely will be the same with abilify. Hopefully your CTO ends soon 🙏
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Thankyou mate 🙏
 
@Invegatorture Many thanks for the replies. So it seems like the way the drug is presented means that it's impossible to titrate the dose. It comes as pre-filled syringes and the clinician injects the contents of said syringe.
 
I’m losing hope that I’m ever going to be able to feel cannabis again. I’ve tried even with high dose concentrates and feel pretty much nothing.
 
Well, be aware that in the UK we conducted studies in which people were given a mixture of CBD and THC and they all ended up giggly and having a great time. But with THC alone, the results were TOTALLY different. Most people suffered extreme anxiety along with time distortion and a host of other unpleasent effects.

Put simply, the old fashioned 'gold seal' and 'Thai' we used to get is as differtent to the skunk so common today as day is to night.

BTW CBD appears to have pretty robust antipsychotic activity.

Put simply, nature gave us a herb that contained both a psychedelic AND a compound that prevented psychosis. What did we do? Selectively breed out that compound that prevented the psychosis.

Grisham's law in action.
 
I still suffer from dissociation, which is the most pronounced of whatever symptoms from Invega Sustenna still remain. This is probably my biggest hurdle.

Because of dissociation, I've been experiencing daydreams in which I see myself in the third person as if I'm looking through another's eyes. Lately, I've been able to recall more and more bits of myself and I suspect when I recall all of it totally it will be my last marker for "full recovery"; once I am fully back in body, in other words.

Has anyone experienced something similar?
 
Well, I am feeling okay so far after two energy drinks each containing 300 mg caffeine. No I don’t drink two of those everyday.

I have work today and it is a 4 hour shift so I hope I am able to be somewhat fast so I can get enough done!

(I worry a lot about this medication making me slower at work.)
 
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