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Misc Codeine interactions with Anti-Psychotics?

ChemicallyEnhanced

ChemicallyEnhanced

Bluelighter
Joined
Apr 29, 2018
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Some sources online say the antipsychotic decreases it's effects, others they they potentiate each other, specifically the sedation?

Wondering about Quetiapine (Seroquel) or Chlorpromazine (Thorazine), specifically?
 
I would have to assume thorazine specifically would potentiate it, being the drug that promethazine is derived from. The euphoria will be blunted and the downstream dopamine will be blocked aswell as serotonin. Sedation will be increased. If you're looking for an objectively fun time, it's not what you want. If you wanna fall asleep and forget your issues a few hours, that's probably a good combo.
 
Seroquel and bupre had no potentiating or synergizing for me. But this was with bupre, not sure how it will react with codiene.

But when I took my night dose of bupre and seroquel, I would lay awake from the bupre and the Seroquel then took hrs to help me sleep eventually but always was wide awake after my night dose of bupre and seroquel combo for 2hrs or so.
 
In my experience both thorazine and compazine (also a antipsychotic) potentiate any opiate by alot. !00mg's of thorazine with my morphine had me nodding like crazy Seroquel fucking wuith my breathing a few times when i was prescribed it alongside morphine. Or it felt like it did anyway. abilify and latuda both seemed to have no effect on opiates. Zyprexa just seem to stop some of the itching from opiates
 
paranoid android said:
In my experience both thorazine and compazine (also a antipsychotic) potentiate any opiate by alot. !00mg's of thorazine with my morphine had me nodding like crazy Seroquel fucking wuith my breathing a few times when i was prescribed it alongside morphine. Or it felt like it did anyway. abilify and latuda both seemed to have no effect on opiates. Zyprexa just seem to stop some of the itching from opiates
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Seroquel also fuck with my breathing at night that gave me panic attacks at and as soon as I dropt my seroquel dosage down to just 25mg most of those side subsided. But for me still no extra sedation but with bupre once again not Codeine
 
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