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Miscellaneous Best & Worst Drug Crosses You've Ever Done

Best: AMT and LSD — fuzzy, blurry, melty, gorgeous. LSD four hours after AMT so that the delayed psychedelia of the latter synergises as much as possible with the acid. It also works brilliantly dropping the two at once, in which case the acid rides on a serotonergic wave and then the AMT visuals take over once the acid is waning.

Worst: Weed and mushrooms or LSD. Mushrooms after a long night of drinking. I do love some beers or wine on a 4-sub tryptamine or LSD comedown though.

Would like to try: mescaline and LSD.
 
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Opiates + Nicotine
Fuck yeah. Nothing like smoking a cig while the opioid kicks in. A junkie friend of mine used to say that her idea of Heaven was an IV drip of heroin and a 3ft-long cigarette. 🤣

Worst for me were the combos we've all been warned about:
Alcohol + benzodiazepines
and
Alcohol + barbiturates

On the former I've wrecked cars that I don't remember driving.
On the latter I've awakened in ICU on a ventilator having lost a couple days in a coma-- twice. And there was very little alcohol involved, plus my tolerance was high.
Barbs are not to be fucked around with.
 
Worst combos I've done are alcohol+benzo and weed+LSD.

One time when I was 18 or 19 I decided to just drink some straight liquor after having some benzos prior, dont remember which ones. I was leaving to go home and suddenly the rest of the night is black. I was apparently brought home by cops after neighbors called them as I was trying to go into my house but I kept trying to open other people's doors.

One of my first really bad trips were due to smoking weed. Hard to put into words of how the experience was but it certainly was not a good time.
 
Worst: Weed and mushrooms or LSD. Mushrooms after a long night of drinking. I do love some beers or wine on a 4-sub tryptamine or LSD comedown though.
Have you ever mixed LSD and mushrooms? I can take either of the two in pretty extraordinary amounts and have a great time, but if I mix even minute amounts of the two with one another I'll end up experiencing what I call "running out of RAM", where my short term memory gets so small I can't even form meaningful thoughts for hours so I just end up stuck in my body waiting to be able to think again.
 
I don’t think I’ve had any bad drug combos, but best are definitely:

MDMA + ketamine/nitrous
LSD + ketamine/nitrous

In general though I don’t like combining drugs for recreational use. I can’t imagine combining MDMA and LSD for example let alone LSD and shrooms. That sounds way too intense for me.
 
Candyflips are amazing, one of the most magical things you can experience.

Crack and heroin just makes you feel fucking amazing, A+.

If you're some kind of true purist anarchist with no regard for the safety and wellbeing of yourself and anyone around you, alcohol and benzos will have you black out and cause absolute mayhem for days on end but you will eventually sober up and have to face the consequences
 
Candyflips are amazing, one of the most magical things you can experience.

Crack and heroin just makes you feel fucking amazing, A+.

If you're some kind of true purist anarchist with no regard for the safety and wellbeing of yourself and anyone around you, alcohol and benzos will have you black out and cause absolute mayhem for days on end but you will eventually sober up and have to face the consequences
So some people say, but I’m sure I would feel overstimulated and overwhelmed. Plus, I don’t know about the safety profile… and I don’t have an urge to do it anyway. I’ve already lost the magic in terms of MDMA too.

Sadly don’t find crack + h anything special. Maybe it needs to be IV but I’m not willing to do that. I’ve IVed pure cocaine before and it was worth doing a couple times, but I’m not doing it again. And I don’t like downers.
 
Ill list some for now as im tired...

Molly + Alcohol + Weed while wd from opioids actually felt amazing, and felt more euphoric with each drink i took although i was wd like i said.

Psilocin + Percocet gave me an intensely epic trip that turned bad, but then good.

I have so many to mention, but maybe amother time i need sleep.

Well right now im on Nutmeg, weed, diphenhydramine. Chlorpheniramine, Xanax, Subutrx, menthol cigs, coffe, chocolate, and potent Weed as usual.
 
Well right now im on Nutmeg, weed, diphenhydramine. Chlorpheniramine, Xanax, Subutrx, menthol cigs, coffe, chocolate, and potent Weed as usual.
"Nutmeg"? Light doses mixed with other stuff? Always wondered about that. I read on experience report wher the guy swore on a tablespoon a day. That's a light dose but it built up over days since the stuff lasts so long and he said he just ended up on a long "very stoned".
 
"Nutmeg"? Light doses mixed with other stuff? Always wondered about that. I read on experience report wher the guy swore on a tablespoon a day. That's a light dose but it built up over days since the stuff lasts so long and he said he just ended up on a long "very stoned".

Reasons i need to stop dosing right before going to sleep... lol
 
DMT after having used methamphetamine within the past week was a big mistake! I had to learn the hard way that stimulants and psychs do not mix!
 
"Nutmeg"? Light doses mixed with other stuff? Always wondered about that. I read on experience report wher the guy swore on a tablespoon a day. That's a light dose but it built up over days since the stuff lasts so long and he said he just ended up on a long "very stoned".
My ex back in the day made these weird nutmeg extract pills … we took a shitload & mixed it with other stuff. It was so weird because the whole time we were tripping we were like “are we tripping?”

That went on for days, we did really weird stuff and kept going for walks everywhere smoking weed. We finally fell asleep after a couple days and when we both woke up we were like “holy shit I’m finally not tripping anymore!” It was way more obvious that we were tripping when we finally weren’t anymore.
It was very weird like a dream for those days.
 
Mescaline and DMXE... I felt like I offended Mescalito with this combo.
Ha, I had just found my old copy (first edition but raggedy) of The Essential Psychedelic Guide by DMT Turner. That guy (RIP) had info on a whole lot of combos. I just read this same thing but his was about ketamine. Here is from the book:

When one takes a natural psychedelic like mescaline, they often come into contact with age old entities of that realm. With mescaline I find I become that branch of a living entity, often called Mescalito, who has existed since humans first ingested psychoactive cacti. . Mescalito can be viewed as being the conglomeration of experiences of all mescaline users. It feels as though when I take mescaline I am the "eye" of mescalito, and that he experiences through me. Mescaline has experienced much during his 3000+ year lifetime. However, my introducing him to a powerful synthetic anesthetic/psychedelic left him shocked, stunned and confused. It was as serious insult on my part to force this experience on Mescalito, especially since omens were telling me not to do it.
It seems as though the "entities of the natural psychedelic realms are adverse to having their realms polluted by people combining them with K. I also feel these entities frown upon excessive or indiscriminate use of K by itself.



We have to keep in mind this was in the early 1990's. Ketamine was not popular. Terrence McKenna talks of a large empty room when he tried it which is what I got in 1990 after 15 tries. Used a few vials of Ketaset IM over that summer. But now that it has existed it is possible that a morphic resonance has occurred in the last 30 years with ketamine users "filling in" that empty room with experience, much like DM Turner was attributing to mescaline. Just a thought. He said it combined nicely with LSD. So that variable makes me think I am wrong.

But if tryptakid states the same in 2025, then maybe it has nothing to do with morphic resonance. I have to keep in mind DM Turner said he got addicted to ketamine and DMT along with mushrooms helped him back away.
 
Ha, I had just found my old copy (first edition but raggedy) of The Essential Psychedelic Guide by DMT Turner. That guy (RIP) had info on a whole lot of combos. I just read this same thing but his was about ketamine. Here is from the book:

When one takes a natural psychedelic like mescaline, they often come into contact with age old entities of that realm. With mescaline I find I become that branch of a living entity, often called Mescalito, who has existed since humans first ingested psychoactive cacti. . Mescalito can be viewed as being the conglomeration of experiences of all mescaline users. It feels as though when I take mescaline I am the "eye" of mescalito, and that he experiences through me. Mescaline has experienced much during his 3000+ year lifetime. However, my introducing him to a powerful synthetic anesthetic/psychedelic left him shocked, stunned and confused. It was as serious insult on my part to force this experience on Mescalito, especially since omens were telling me not to do it.
It seems as though the "entities of the natural psychedelic realms are adverse to having their realms polluted by people combining them with K. I also feel these entities frown upon excessive or indiscriminate use of K by itself.



We have to keep in mind this was in the early 1990's. Ketamine was not popular. Terrence McKenna talks of a large empty room when he tried it which is what I got in 1990 after 15 tries. Used a few vials of Ketaset IM over that summer. But now that it has existed it is possible that a morphic resonance has occurred in the last 30 years with ketamine users "filling in" that empty room with experience, much like DM Turner was attributing to mescaline. Just a thought. He said it combined nicely with LSD. So that variable makes me think I am wrong.

But if tryptakid states the same in 2025, then maybe it has nothing to do with morphic resonance. I have to keep in mind DM Turner said he got addicted to ketamine and DMT along with mushrooms helped him back away.
I find this way (morphic resonance) of conceptualizing or understanding the psychedelic experience to be quite compelling. I also feel that my preference moving forward would be to not mix plant-based psychedelics with drugs like K or DMXE. I do think that LSD and Ketamine combine nicely and I personally attribute that to LSD always giving me a more synthetic or alien vibe which coalesces well with ketamine's synthetic/robotic headspace. If there are spirit teachers attached to either, I doubt they are of this world.
 
Ha, I had just found my old copy (first edition but raggedy) of The Essential Psychedelic Guide by DMT Turner. That guy (RIP) had info on a whole lot of combos. I just read this same thing but his was about ketamine. Here is from the book:

When one takes a natural psychedelic like mescaline, they often come into contact with age old entities of that realm. With mescaline I find I become that branch of a living entity, often called Mescalito, who has existed since humans first ingested psychoactive cacti. . Mescalito can be viewed as being the conglomeration of experiences of all mescaline users. It feels as though when I take mescaline I am the "eye" of mescalito, and that he experiences through me. Mescaline has experienced much during his 3000+ year lifetime. However, my introducing him to a powerful synthetic anesthetic/psychedelic left him shocked, stunned and confused. It was as serious insult on my part to force this experience on Mescalito, especially since omens were telling me not to do it.
It seems as though the "entities of the natural psychedelic realms are adverse to having their realms polluted by people combining them with K. I also feel these entities frown upon excessive or indiscriminate use of K by itself.



We have to keep in mind this was in the early 1990's. Ketamine was not popular. Terrence McKenna talks of a large empty room when he tried it which is what I got in 1990 after 15 tries. Used a few vials of Ketaset IM over that summer. But now that it has existed it is possible that a morphic resonance has occurred in the last 30 years with ketamine users "filling in" that empty room with experience, much like DM Turner was attributing to mescaline. Just a thought. He said it combined nicely with LSD. So that variable makes me think I am wrong.

But if tryptakid states the same in 2025, then maybe it has nothing to do with morphic resonance. I have to keep in mind DM Turner said he got addicted to ketamine and DMT along with mushrooms helped him back away.
I've felt for some time that psychedelics develop a conglomeration of the trips of all the users they've had. Thus, LSD has a higher percentage of bad trips since so many people took it initially without the support of ceremony, intent, or shamanism. More bad trips makes a higher predilection for bad trips in LSD's "gestalt" (I know I'm not using that word right but can't think of a better one)

Love that book.
 
Selegiline and GHB were pretty bad. Selegiline is great on itself, we know about ghb. Useful for some, but better not touch with a pole in general.

However when taken together, it almost killed me. I was in such a total haze, couldn't think straight. Dissociative in the worst way with black outs. Heart rate through the roof, I think I had an epileptic fit also, but don't remember clearly.

I woke up alive, bruised, there is something very bad, directly, about this combo. Perhaps it is the dopamine raising properties of GHB combined with selegiline which is a maoi-b, which makes this so bad? Not going to try again to test it out.
 
Meth + DMT was by far the worst combo ive ever done involving a psychedelic.

I was coming down from the meth and I have no idea why I decided to smoke DMT but I know ive had historically terrifying experiences and have tried to find ways to combat the fear, two of them being using heroin and also ketamine before I blast off so that I can find a place where im not scared out of my mind.
Nothing has worked btw. But when I smoked DMT while still under the influece of meth thinks were utterly demonic, I began crying and ran to jump in bed with my mum literally. I was sure I was dying.

I know ill never smoke DMT again.

Anything with meth is bad, but LSD and meth was particularly bad too.

Ketamine and LSD is fantastic!
 
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