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Misc Melatonin, how does it feel?

username_required said:
melatonin is not sedative or hypnotic whatsoever, it simply does not serve that biological function. anyone who claims otherwise is just feeling placebo
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Well could be but sleeping during a MDMA comedown mostly involves late bedtime and tossing and turning.
The pre ban under the counter Melatonin at 9 mg completly overrid that, anytime. With me and the others i shared it with.

Then they banned it to be reintroduced with the lowered dose and it never worked again, no slurrring or stumbling and falling asleep ?

edit : equivalent dosages of the old and new version.
 
i tend to agree with users who suggest a placebo effect.
while i myself never felt anything from taking melatonin, i have a friend who always needs a larger amount of drugs to feel anything, but curiously the melatonin did help him fall asleep faster (unless it was something else)


jasperkent said:
What I like most about it is that, for me, it induces vivid dreaming. Some people report nightmares, but I very rarely have bad dreams and even then they usually resolve somehow before I wake up. My dreams are crazy, colorful, complicated, lengthy, often amusing, and always quite fascinating.
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but when i read this i want to give it another shot, this time looking for dream enhancement.
i also do have vivid dreams which i can turn around when i don't like (unfortunately i also have night terrors which i can't influence whatsoever and which were not influenced by melatonin)
 
username_required said:
melatonin is not sedative or hypnotic whatsoever, it simply does not serve that biological function.
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You had the first part right, but the second part is very wrong. It's actually one of the few "drugs" that does serve a biological purpose... melatonin is literally an endogenous hormone, it is an analog of serotonin, and has a very clear and essential biological purpose/process.
 
Quasimoto said:
You had the first part right, but the second part is very wrong. It's actually one of the few "drugs" that does serve a biological purpose... melatonin is literally an endogenous hormone, it is an analog of serotonin, and has a very clear and essential biological purpose/process.
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i’m well aware that it’s endogenous, hence my wording. melatonin is not an endogenous sedative/hypnotic hormone and hence does not serve that biological function. it serves to regulate the circadian rhythm, and can be helpful in regaining/resetting your circadian rhythm, but melatonin itself isn’t sedative or hypnotic and the vast majority of people who believe it is are just experiencing placebo (which can be extremely powerful in regards to sleep)
 
username_required said:
melatonin is not an endogenous sedative/hypnotic
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I didn't say it was, only that it does serve a purpose regarding sleep. I think we just misunderstood eachother.

username_required said:
but melatonin itself isn’t sedative or hypnotic and the vast majority of people who believe it is are just experiencing placebo (which can be extremely powerful in regards to sleep)
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Yeah, I’ve never felt anything productive from it. From doses of 500ug to 100mg. Nothing. I tell everyone it's a waste of money unless you are jet-lagged.
 
Quasimoto said:
Yeah, I’ve never felt anything productive from it. From doses of 500ug to 100mg. Nothing. I tell everyone it's a waste of money unless you are jet-lagged.
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I’ve for the most part found it pretty unhelpful. There have been a couple times that I can remember feeling that it had possibly increased my sleep quality though obviously that’s pretty much impossible to determine. The past week I’ve been taking it every night along with my clonidine before I sleep to see if it has any effect on my sleep quality. I can’t sleep at all without taking my clonidine so I’m wondering how that effects my circadian rhythm since it sort of seems like I effectively don’t have one at all (if anyone knowledgeable about this has any information about this please feel free to enlighten me!). I’ve noticed the past 2 days I’ve worked up a little earlier than I normally and feel a bit more well-rested. Maybe it’s the melatonin, maybe it’s coincidence, but I can say for absolute certain it has not helped me to fall asleep whatsoever.
 
I've had luck using it to sleep at 0.3mg a night paired with weed. not gonna put you up for the night but I've always managed to sleep well. never done it long-term, but only because I'm not good with forming habits. I just get subtly sleepy, I'm really not sure you'd have anything interesting with a large dose, staying awake through it (on any dose that I've tried) just makes me groggy
 
From all the fantastic responses so far and the research I have done, it seems that melatonin is a very subtle drug with extremely limited almost imperceptible psychoactive effect.
Apparently, some melatonin receptor antagonist including a non-selective antagonist have already been developed and they are used for studying the effects of melatonin in lab rats and other animals. it’s a suggested that these compounds have antidepressant effects, something I think is quite interesting.
 
It's never done anything for me personally, and doses over 10mg actually made me more restless. A lot of people swear by it though.
 
i feel 6mg like a pleasant sedative with some minor hypnotics effects.....and that is the time that u must go to bed...'cause effect very quickly wear off as by me.....also a strong antioxidant...it's a good supplement...non addictive also
 
Nas47 said:
i feel 6mg like a pleasant sedative with some minor hypnotics effects.....and that is the time that u must go to bed...'cause effect very quickly wear off as by me.....also a strong antioxidant...it's a good supplement...non addictive also
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Do you mean Ativan ( lorazepam)?
 
Nas47 said:
i feel 6mg like a pleasant sedative with some minor hypnotics effects.....and that is the time that u must go to bed...'cause effect very quickly wear off as by me.....also a strong antioxidant...it's a good supplement...non addictive also
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Thats my experience too with the 'before the regulation' 3 mg pills.
Not a Dutch brand, more a nootropic like company. Placebo :unsure:
Like a God s existence you can never rule that out,
but it was consistent !

During MDMA comedowns. Something that have us stumble to bed,
which otherwise would be. Nights of tossing/ turning & insomnia.

Sounds like the difference between good and bad Valerian.
 
Dreamflyer said:
It's never done anything for me personally, and doses over 10mg actually made me more restless. A lot of people swear by it though.
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Like Nas47 said
emkee_reinvented said:
Thats my experience too with the 'before the regulation' 3 mg pills.
Not a Dutch brand, more a nootropic like company. Placebo :unsure:
Like a God s existence you can never rule that out,
but it was consistent !

During MDMA comedowns. Something that have us stumble to bed,
which otherwise would be. Nights of tossing/ turning & insomnia.

Sounds like the difference between good and bad Valerian.
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They sell 12mg pills at the store up the road a few of them would help a little, but only if used occasionally for me.
 
I take approximately 60mg/night. I don't "feel" anything, but I do fall asleep quickly, but wake up about 4 hours later, wide awake.

You can look into DSIP, which is a peptide. You would have to inject it subcutaneously. I've done it for a few months. It helps you reach REM sleep. It's called Deep Sleep Inducing Peptide (DSIP).
 
When I was taking Piracetam every day, it negatively affected my sleep. So I started 3mg Melatonin nightly and I did sleep. It gave me a short lasting tired and drowsy feeling. No high of any sort and if you didn't lay right down to sleep it wore off quickly.
Which is weird, because it always gave me residual drowsiness the next morning. The next day, I felt that kind of almost comfortable "can't wake up" fuzzy feeling for an hour or so.
I wasn't doing any stronger drugs at the time and I could see how you wouldn't notice Melatonin at all by comparison if you were.
I'm in my 60's now and I've tried it for sleep. It does help me fall asleep, but the vivid dreams make me wake up too early.

It's a tool, not a recreational drug.

It's supposed to be good for potentiating psychedelics used as below, but I've never tried it.


Then I found another reference to using Melatonin to potentiate psychedelics in an article describing various ways to potentiate Mescaline. This is an excerpt from the article-

"Melatonin - I have heard a report that Melatonin ( available in most Health food stores ) will potentiate the effects of ingesting mescaline. The preferred and most effective method is to take 10-15mg before bed, a week in succession before the trip. If this is not practical, 20-25mg may be taken at least 12 hours before the actual trip. The later method works but is not as efficient as the week long method. It is said that the "7 day boost" used in conjunction with beta-carbolines (below) results in an ultra-euphoric boost."

I was very skeptical of these claims that repeated nightly high doses of Melatonin could potentiate psychedelics until I tried for myself with 2CE. On a few occasions I tried taking 6-24 mg of Melatonin each night for as many nights in advance as I could and then the next day would eat or insufflate 2CE. My resulting trips seemed longer, more visual and euphoric. The first time I preloaded on Melatonin and snorted 2CE I assumed it was a coincidence that the trip seemed longer and more visual. However, after trying this combination over and over I concluded it did in fact seem to work.

I've subsequently tried preloading on Melatonin before blotter experiences and before HBW experiences. What I usually do is starting 4 or 5 nights (though sometimes up to a week in advance) before a trip I take like 6-9 mg of Melatonin. I slowly increase my dosage each night to where the night before my trip I usually am on 21-24 mg of Melatonin.
fourty6andtwo

Thread 'Melatonin potentiating psychedelics?'

Anyone ever tried taking a few melatonin tabs with some other tryptamine...I know its not psychoactive on its own but might it have synergistic effects with other tryps? hmm...

It is N-Acetyl-5-methoxytryptamine after all.
 
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