What’s Safe To Take While On Methadone

[beastm0ded]

I’m curious as to what drugs people take who are on methadone. I currently am on 30 mg per day but I was at one point 120. I want to be able to dabble with some stuff now that I’ve been clean from fentanyl for so long. I feel comfortable enough n have had the urge. I just want it to be safe. Alcohol and methadone is terrible from what I hear. What would you guys recommend? Aside from weed as I smoke daily already.

 

[beastm0ded]

Didn’t realize I had no title lol sorry

 

[goodjunkie]

Hi im on 75mg methadone daily and i find promethazine goes well with methadone and opiates in general. An other good one is pregabalin (brand name is Lyrica) to take with methadone. There is synergy effect. Benzo is also popular but i dont take them because i gotta do pisstest for parole

 

[Coffeeshroom]

At that dose of 30mg, you can take almost anything with it, all depending on your tolerance of other said drugs you thinking of adding to the list.
But some things you can try depending on the outcome you want;

Stimulants
Gabapentenoids
Antihistamines
psychedelics

Um just some to mention.

 

[Cult315]

While I 100% do not recommend it, and I can’t exactly vouch for this specific combo but I’d assume it’s just like the others, I find meth(or really any amphetamines) and opiates is a very good combo. Before I finally managed to kick subs I was doing both and my productivity was through the roof lol. Meth by itself makes it so I can work/clean or whatever when I have to with no complaints. The sub/meth combo made me want to work/clean, like non stop. My house, garage, my place of work were all in immaculate shape when I was doing both lol. Not that anything is trashed or unkept now, I’m just not as driven to constantly clean, organize and fix everything. Meth by itself makes me more want to fuck and play COD lol

 

[Dextro .45]

DDI’s are very important to know and understand yes…..how Methadone is metabolized (particularly liver enzymes) other drugs being metabolized by the same liver enzymes could pose dangerous levels of said drug

I’ve been on every opioid 15 years already. Currently Methadone 80/100/125mg daily depending

Brompton Cocktail ….my standard daily regimen, slight variations and different combinations but the standard I would say:

Methadone 100mg
Ritalin (Methylphenidate) 60mg IR
Valium (Diazepam) 10mg X 2
Xanax (Alprazolam) 0.5-1mg
Lyrica (Pregabalin) 150-300mg
Ethanol / Gin 2.oz 3-5 drinks over 6h or so

All tablets / capsules pulverized into a single glass…..little warm water to dissolve all powder, add cold sweet ora ge juice to mask to bitter taste, drink. 30-45min onset starts to creep in on a fasted state and within the hour I’m feeling full effects

The dopaminergic stimulant- Ritalin (Methylphenidate) is essential to the opioid to enhance its pain killing propertied, reduce any sedation caused by the opioid and minimize cognitive impairment. The anxiolytic meds are essential especially the robust muscle relaxation properties of Diazepam and anticonvulsant effects of Pregabalin.

Indica cannabis before night
Ketamine is also very effective for analgesic/anxiolytic/antidepressant

I’m a tolerant individual to all compounds and have taken lowest therapeutic doses possible, and gradually increased as tolerance / pain levels increased .

 

[paranoid android]

Try getting ahold of some cyclizine its supposed to go great with methadone

 

[3DQSAR]

Try getting ahold of some cyclizine its supposed to go great with methadone

In the UK at least, cyclizine's interaction with methadone is remembered due to the HR disaster that occurred in the 1980s. Users discovered that the compound analgesic Diconal (dipipanone + cyclizine) produced a unique euphoria on IV administration. When that became a major health hazard, Diconal prescribing almost stopped. At this point opioid users discovered that methadone + cyclizine produced a similar effect.

The problem (as I understand it) is that the euphoric the mixture produces only lasts for 20 minutes so it was common for someone to obtain a box of cyclizine and whack up another pill (or two) every 20-30 minutes. Since cyclizine causes seizures in overdose, I'm sure you can figure out why it's not remembered fondly.

 

[LargeAppetite]

Methadone and benzos can be risky. The "Brompton cocktail" can be risky, especially without all the ingredients. Nobody and no body likes a half ass cocktail. Know your tolerance, do your research. 30mg's is not much but don't go playing with fire after you went through the pain of kicking the fetty. You are on methadone and off fetty so you can live.

 

[3DQSAR]

Methadone and benzos can be risky. The "Brompton cocktail" can be risky, especially without all the ingredients. Nobody and no body likes a half ass cocktail. Know your tolerance, do your research. 30mg's is not much but don't go playing with fire after you went through the pain of kicking the fetty. You are on methadone and off fetty so you can live.

Sci-Hub | Cyclizine Abuse among a Group of Opiate Dependents Receiving Methadone. Addiction, 84(8), 929–934 | 10.1111/j.1360-0443.1989.tb00766.x

 

[Dextro .45]

Methadone and benzos can be risky. The "Brompton cocktail" can be risky, especially without all the ingredients. Nobody and no body likes a half ass cocktail. Know your tolerance, do your research. 30mg's is not much but don't go playing with fire after you went through the pain of kicking the fetty.

YES. Absolutely so....

It should be stressed this is for tolerant individuals only who have built up a tolerance over years and years (10-15 years in my case). And you're Very knowledgeable about your meds....their MOA, any DDI's, active metabolites, half life & clearance, etc.

In safe, low therapeutic doses, tailored to a specific individual.....the legendary Brompton Cocktail is unmatched and the true Holy Grail.....it's like a Speedballs older more mature brother

Adding a dopaminergic stimulant (d-Amphetamine) to an Opioid (Morphine Sulphate) to severely injured soldiers during WWII SIGNIFICANTLY enhanced the analgesic painkilling properties of the Opioid. Lower dose of opioids were still effective, while reducing sedation and improving cognitive function.....also having very robust mood-boosting & antidepressant properties

There are many variations of the oral Brompton Cocktail, some aren't necessary in cases, such as Indica Cannabis, Chloriform, and Cocaine is rarely used at all. Diacetylmorphine (Heroin) is still widely used, but often substituted with Hydromorphone, Methadone, Oxycodone. Cocaine is often substituted with d-Amph, d-Meth, Methylphenidate (Amphetamines in general)

Diazepam 10mg and Pregabalin 300mg are both essential components of the modern hybrid Brompton Cocktail....and Ethanol has ways been a staple. Original formulation calls for Gin. Currently Ketamine is a very valuable and safe drug to add to the formulation

For severe and/or chronic pain in tolerance patients....a properly formulated Brompton Cocktail is a ticket to pain free, comfortable and happy heaven for 5-8 hours lol

Be safe