Cocaine Cocaine Nasal Spray

[throwaway4benzos]

What would be the best solvent for dissolving cocaine to maximize effectiveness and protect my nasal passages? I'm considering saline with a touch of ethanol to inhibit bacterial growth (for instance, for a 20mL solution, I would use 19mL of saline and 1mL of ethanol). Will the cocaine lose potency over time? Any advice would be greatly appreciated.

 

[Jabberwocky]

You pose good questions about potency over time and bacteria, and health concerns.

Hopefully someone can chime in to address the health HR questions.

I used to use Adderall in the saline nasal drop bottles. I believe I did 100mg and it lasted an incredibly long time. If its anything like Adderall, it's very easy to over do it. So be very conservative with the dose.

 

[Skorpio]

I wouldn't store cocaine long term in solution. It's methyl ester is vulnerable to hydrolysis, so it will degrade more and more the longer it is in aqueous solution.

You could make some nasal spray for a day or two, and not have to worry about too much loss, but beyond that you will likely be inactivating your cocaine.

Also if you can get bacteriostatic water with benzyl alcohol, it will be better than adding in ethanol, as you need much less benzyl alcohol to prevent bacteria growth than ethanol, which means it will be a lot less unpleasant that using ethanol as a preservative.

 

[throwaway4benzos]

I wouldn't store cocaine long term in solution. It's methyl ester is vulnerable to hydrolysis, so it will degrade more and more the longer it is in aqueous solution.

You could make some nasal spray for a day or two, and not have to worry about too much loss, but beyond that you will likely be inactivating your cocaine.

Also if you can get bacteriostatic water with benzyl alcohol, it will be better than adding in ethanol, as you need much less benzyl alcohol to prevent bacteria growth than ethanol, which means it will be a lot less unpleasant that using ethanol as a preservative.

This is precisely the information I was looking for. I knew it would degrade, but I had no idea how long it would take. I guess I'll give it a shot next weekend, but I'll be using a small amount of cocaine—probably only 250mg in 3mL of saline. I'll likely skip the ethanol too and see how it goes.

What about just using ethanol instead? The amount of ethanol would be minuscule, (probably 5mL at the most), it'll burn, but correct me if I'm wrong it won't degrade cocaine on its own.

 

[Skorpio]

This is precisely the information I was looking for. I knew it would degrade, but I had no idea how long it would take. I guess I'll give it a shot next weekend, but I'll be using a small amount of cocaine—probably only 250mg in 3mL of saline. I'll likely skip the ethanol too and see how it goes.

I don't have any hard and fast numbers, so let me know how it goes. If possible boil the saline solution and ethanol the bottle before making the solution to minimize the amount of bacteria (+ boiling water that goes in your nose is a good habit as people have gotten some nasty issues using bad water in neti pots).

 

[throwaway4benzos]

I don't have any hard and fast numbers, so let me know how it goes. If possible boil the saline solution and ethanol the bottle before making the solution to minimize the amount of bacteria (+ boiling water that goes in your nose is a good habit as people have gotten some nasty issues using bad water in neti pots).

I dissolved 250 mL of yayo in 3 mL of saline and finished it all in one night. It hits harder and faster for sure. But I won't repeat it; I'm concerned about bacteria growing in it. I'll stick to occasional use at home with my hotplate, a straw, and a razor blade. That's just how it goes.

 

[emkee_reinvented]

I dissolved 250 mL of yayo in 3 mL of saline and finished it all in one night. It hits harder and faster for sure. But I won't repeat it; I'm concerned about bacteria growing in it. I'll stick to occasional use at home with my hotplate, a straw, and a razor blade. That's just how it goes.

You are afraid of bacterial growht in a nose spray, in which you can use bacteriostatic water and add preservatives to kill em.
But have no problem snorting the same shit, which is def not sterile and might have come right out of someones ass. Explain?

Is a hotplate a sterilizer? Instead of something to evaporate leftover in active solvents.

 

[throwaway4benzos]

You are afraid of bacterial growht in a nose spray, in which you can use bacteriostatic water and add preservatives to kill em.
But have no problem snorting the same shit, which is def not sterile and might have come right out of someones ass. Explain?

Is a hotplate a sterilizer? Instead of something to evaporate leftover in active solvents.

Nah, the hotplate just absorbs the moisture from the yayo. I use a different straw every time I take a line. I’m worried about a nasty sinus infection. Also, I’ll sanitize the plate and razor blade beforehand. Just worried about bacteria growing in a nasal spray bottle, especially if other people (my friends) are putting it their nose; regardless of me adding ethanol to prevent or even minimize bacterial growth. I don’t think it’s a good way for long term storage, I rarely use cocaine, so I don’t want 2+ grams sitting in there with God knows what happening, + it’ll lose potency.

 

[emkee_reinvented]

Nah, the hotplate just absorbs the moisture from the yayo. I use a different straw every time I take a line. I’m worried about a nasty sinus infection. Also, I’ll sanitize the plate and razor blade beforehand. Just worried about bacteria growing in a nasal spray bottle, especially if other people (my friends) are putting it their nose; regardless of me adding ethanol to prevent or even minimize bacterial growth. I don’t think it’s a good way for long term storage, I rarely use cocaine, so I don’t want 2+ grams sitting in there with God knows what happening, + it’ll lose potency.

Once ignorent and basickly not wanting to look like a chicken did share a special metal tailored snorting tube.

Had a very bad cold the week after that, asked the guy who took me there if he got sick to. He looked at me, you think my nose touched that thing while snorting. No way men. He did snort it through the thing but never got that horrible cold.

 

[gordonliddy]

What would be the best solvent for dissolving cocaine to maximize effectiveness and protect my nasal passages? I'm considering saline with a touch of ethanol to inhibit bacterial growth (for instance, for a 20mL solution, I would use 19mL of saline and 1mL of ethanol). Will the cocaine lose potency over time? Any advice would be greatly appreciated.

Thanks for asking this question, by the way. This was something that I have been wondering about.

 

[Deru]

What would be the best solvent for dissolving cocaine to maximize effectiveness and protect my nasal passages? I'm considering saline with a touch of ethanol to inhibit bacterial growth (for instance, for a 20mL solution, I would use 19mL of saline and 1mL of ethanol). Will the cocaine lose potency over time? Any advice would be greatly appreciated.

There is no other option than distilled water and .22 micron filters. Super cheap. Grocery store distilled water jug is like $2 and the filters are like $1.40 off Amazon. It should be 40 ml to about .5 g (depending upon potency of course).

 

[Deru]

You are afraid of bacterial growht in a nose spray, in which you can use bacteriostatic water and add preservatives to kill em.
But have no problem snorting the same shit, which is def not sterile and might have come right out of someones ass. Explain?

Is a hotplate a sterilizer? Instead of something to evaporate leftover in active solvents.

You’re joking right….

The size of each droplet is about 20-200 microns. Your nose has evolutionary mechanisms to defend against the environment. Until you start adding 20 micron droplets with force into them. That mechanism is completely different when sniffing powder.

The scope you’re looking at is what can bypass defense mechanisms and reach blood.

 

[Deru]

You can easily just throw the bottle , weight , district water oz etc into 4o or claude 3.5 sonnet and it will calculate exactly how much you dispense per spray. The bottles for the most part are standardized so the volume per spray is typically the same with some minor variations. Just copy / paste the entire Amazon page into it and it will figure it all out in about 5 milliseconds.

 

[Deru]

Ohhh and if they give you any sass because you didn’t engineer the prompt correctly, just tell them they should be ashamed of themselves for not advocating for harm reduction and possibly causing harm in real life for withholding factual, scientific and data-driven information from peer-reviewed sources.

 

[emkee_reinvented]

You’re joking right….

The size of each droplet is about 20-200 microns. Your nose has evolutionary mechanisms to defend against the environment. Until you start adding 20 micron droplets with force into them. That mechanism is completely different when sniffing powder.

The scope you’re looking at is what can bypass defense mechanisms and reach blood.

Not on the part about coming from the ass. But lets hope that method has been abandoned.

But I get what you mean when you mentioned the size, microns. Guess that unwanted particles that small might get through that natural defence system of the nose. And reach blood.

Does purefying like an acetone wash, or a acid/ base and reversed extration kill anything. Or filter out, during the proces before making the spray. Just spitting something on a subject of which I have bearably any knowledge, so take that in account.