Miprocin I think is one of the most profoundly "therapeutic" substrances I've ever done... it's like the unique crosstalk-configuration doorway that the molecule unlocks directly connects the voiceless, pre-language, sub-concious "feeling" engines of the brain with the abstraction and conceptualisation cortical structures (those bits maybe best for rational thought and logic) and you can withness both parts converse in a shared language that is usually just not there.
When I first tried it I described it as tryptamine MDMA. I have a much wider range of experiences to compare it to now, but I still think it's a good one. I've known multiple people who think it's good for recalling childhood memories and feelings, the latter of which definitely feels like it relates somewhat to my own comparisons of it to MDMA as well (because MDMA was part of my younger life I mean, not because MDMA also does that for me).
Really curious to try the rest of the 4-HO-xTryptamines now, 4-HO-DET I am interested in as well as 4-HO-DPT particularly, as these seem to be somewhat significant edges on a conceptual shape of uncertain dimensions.
4-HO-DET and 4-HO-DPT are pretty different from 4-HO-MiPT in my experience, for what it's worth. Like more so than comparing it to other 4-substituted tryptamines I'd say, at least in some important ways.
I actually tried to figure this out many years ago. This is the logic I came up with:
5-Substituted Tryptamine = +0
Base Tryptamine = +1
4-Substituted Tryptamine = +2
Methyl Tail = +0
Ethyl Tail = +1
Propyl Tail = +2
Isopropyl Tail = +3
N,N-Diethyllysergamide Backbone = +4
Ergo...
Bufotenine or 5-MeO-DMT = 0 (5-Substituted + Methyl + Methyl)
DMT = 1 (Base + Methyl + Methyl)
Psilocin = 2 (4-Substituted + Methyl + Methyl)
LSD = 4 (Lysergamide + Methyl)
So...
0:
Bufotenine,
5-MeO-DMT
1: 5-MeO-MET,
DMT
2: 5-MeO-MPT, 5-MeO-DET, MET,
Psilocin
3: 5-MeO-MiPT, 5-MeO-EPT, MPT, DET, 4-HO-MET
4: 5-MeO-EiPT, 5-MeO-DPT, MiPT, EPT, 4-HO-MPT, 4-HO-DET,
LSD
5: 5-MeO-PiPT, EiPT, DPT, 4-HO-MiPT, 4-HO-EPT, ETH-LAD
6: 5-MeO-DiPT, PiPT, 4-HO-EiPT, 4-HO-DPT, PRO-LAD
7: DiPT, 4-HO-PiPT, iP-LAD
8: 4-HO-DiPT
And my descriptions:
0: Colorful, Emotional
...
8: Colorless, Cognitive
Bufotenine is almost all color and emotion for me. DMT is mostly the same but slightly reduced in color and slightly more cognitive. Psilocin is pretty similar to DMT for me but with a notable step towards being more like LSD. LSD is a pretty good mix for me, being a good blend of both the traditional tryptamine colors and emotions and stuff and the darker, more dissociative, edgy, and cognitive style of the bulkier synthetic indoles. DPT, 4-HO-MiPT, and ETH-LAD are all good examples for me of psychedelics that are still colorful and emotional enough to feel similar to LSD and the natural tryptamines, but still feel like they're still another step further away from them than even LSD is for me, being even more visionary and in my head and less bright and flashy. 4-HO-DiPT at the extreme end is a drug I have a hard time getting anything but colorless visuals, dissociative visions, and sexy or self-reflective thoughts on, with none of the flashy colors or orgasmic emotions or anything I associate with something like mushrooms.
4-HO-DET has a higher degree of colorful and emotional effects for me than 4-HO-MiPT and a lower degree of colorless and cognitive effects, a lot like LSD, although I also find it to feel the most superficially distinct from LSD of all of the tryptamines I've tried in the
4 category I assume because nothing about the molecule is superficially similar (two ethyls is pretty different from a methyl and a lysergamide backbone and the ring is subtituted on the tryptamine but not on lysergamides). A notably defining quality of ethyl indoles for me is that they are weird in opposition to how methyl indoles feel more familiar and inviting, and 4-HO-DET is no exception for me. It's like a super weird 4-substituted tryptamine that is still pretty similar to mushrooms overall but definitely also a couple steps forward toward being alike LSD and I would say even very alike it, and not as distinct in effect as something like 4-HO-MiPT or 4-HO-DPT. I liked it a lot but more so as a curiosity than because it was fun. I never really felt compelled to keep using it.
4-HO-DPT for me is on the part of the scale where it's so close to the "Colorless, Cognitive" side and far away from the "Colorful, Emotional" side that it starts to become difficult for me to actually get much of the latter kind of effects at all. If I don't take a significantly high dosage of 4-HO-DPT, it will mostly be shadowy auras with vague but dark colors like purple and soft pink, and it doesn't have much emotional or energetic engagement at all, instead being more like a trip where I just lie down and reflect while visions play behind my eyes, should I choose to close them. A lot of people like it but it was difficult for me to reach a place that I actually felt satisfied with with it. It seems like some of the people I've encountered who like it like it because it's so easy and euphoric if dosed high enough to the point that it's been compared to being opioid-like, I could see that. I've also described 4-HO-EPT and EPT as narcotic and see some connection between the EPTs and the DPTs.
I've tried some of the allyls too for the record.... I think the best way to think of allyls is like analogues of propyls. Similar but slightly different overall if you ask me.
For what it's worth I feel like 4-HO-MiPT occupies a special spot being the furthest methyl indole down on the list (the only one in row
5 or higher). Based on my proposed theories that would make it the most colorless and cognitive of all the methyl indoles, meaning that it's the most colorless and cognitive of all the ones that it still the most superficially similar to things like DMT, psilocin, and LSD, which I would say is something I think I agree with. When the methyl is dropped for things like 4-HO-DET and 4-HO-DPT, things seem to get a bit wonkier for me. Not that that makes them bad, just different.
I just wanted to share that based on some of what you were saying there.... I don't hold myself to these theories which are all they are, and I haven't actually reevaluated them in years now, but to be honest I still think the chart is fairly reflective of my own experiences. Make of that what you will.