Opioids Morphine never worked

[Stephy]

Morphine just doesn't work well for some people. For instance, I love the semi synthetic opioids, but no matter how much morphine I take it will not give me nearly the same feeling. Best to just give up and stop taking them

What should I try? I need to get this pain under control!!! It makes me a major bitch to people because I've constantly hurt. Doctors and Everybody's been saying That the pain meds are the cause of the pain and that they are making the pain worse. I don't believe I am an addict I don't believe or didn't believe that the pain meds made my pain worse but they've been drilling it into our head so much so often I'm beginning to doubt myself. I'm beginning to wonder are the pain meds making my pain worse? I have thought about methadone down and other ways to get off the pain meds but Every time I'm without my pain meds the pain is so much worse. My pain meds were just on back order And I was without my payments for over 2 weeks it was horrible... I did my best to just sleep and sleep and sleep to get through it and I slept so much I couldn't even sleep anymore. I got lucky and a friend gave me some Tylenol 3 with Codeine and that helped a lot, but I was taking 4 at a time ever 4-5 hours That was a 120 mg of codine at a time.

 

[Stephy]

Had a similar experience with opioids & dissociatives like @Tranced, the latter didn't want me to do opioids, it was a full psychotomimetic experience with acoustic hallucinations (voices, foreign thoughts in my head) which basically told me to stop fucking with opioids but I didn't listen and it became a mess. Notable that these psychotic features came and went with the morphine, less so methadone or BDPC and absent when doing just dissociatives.

I don't know what B DPC is and I don't know what the associatives are. I don't know a whole lot about drugs but I'd love to get off the opiates howeverMy pain is so horrible. I hate having to take these meds. Done the physical therapy the Chiropractic visits massage the trigger point injections medial branch blocks you name it I've tried it and I can't get the pain to go away. I hate being on these I hate Being scared every time I go to the doctor's follow up visitSomething will go wrong and I won't get my prescript. I hate then going to the pharmacy and hoping nothing bad happens and that I get my prescription. I hate keeping my meds and a safe to make sure nobody steals them and I worry that when I'm and senior citizen someone will steal my pain medication from me and I won't be able to say anything because I have all timers and can't speak up. There are so many reasons I don't want to be on pain medication but I can't get the pain to go away

 

[Stephy]

I've tried I think just about every opiate I think... I haven't tried to kratom but I was kind of scared. I bought it but then started seeing that not all dosages were the same and that getting the right dosage can be tricky and can lead to intestinal problems

 

[G_Chem]

Maybe I should try snorting it? I've never snorted anything before except I tried cocaine once no 3 times And it never worked for me either. Back in the early 2 thousands I tried ecstasy and ended up with serotonin syndrome Instead of getting a buzz. I got a small buzz but it took a s*** load and I Passed out on the floor several times That night. I tried cocaine a couple times but It was not from a trustworthy source so I don't know if it was good stuff or not but it didn't work for me. It was real caky to me but I've never been it before so I don't know what to expect. But to me it seemed like there was a lot of powdery white stuff clogging up my nose, but hey... I'm snorting white powdery stuff up my nose

You could. Rectal is probably the best route from a Harm Reduction standpoint but at the end of the day we use these drugs for a desired effect. Supposedly snorted morphine bioavailability is supposed to be lower than oral but my experience and that of others doesn’t seem to match that.

Cocaine shouldn’t be chalky and shouldn’t be clogging your nose unless your snorting stupid amounts. Sounds cut all to hell. Pure powdered cocaine is almost silky, if you were to take a tiny bit and rub it between your fingers it will melt from the moisture of your hands. It’s also one of the nicest drugs to snort, goes up like butter.

-GC

 

[LucidSDreamr]

That's a really low dose for xr. Normal to not feel much.

If you've never felt a real opioid high....probably best to stop before you open that door because a very large percentage of people go through years of misery or death after their real hit and falling in love with opioids.

This is a significant chance to ruin your life.

 

[Stephy]

You could. Rectal is probably the best route from a Harm Reduction standpoint but at the end of the day we use these drugs for a desired effect. Supposedly snorted morphine bioavailability is supposed to be lower than oral but my experience and that of others doesn’t seem to match that.

Cocaine shouldn’t be chalky and shouldn’t be clogging your nose unless your snorting stupid amounts. Sounds cut all to hell. Pure powdered cocaine is almost silky, if you were to take a tiny bit and rub it between your fingers it will melt from the moisture of your hands. It’s also one of the nicest drugs to snort, goes up like butter.

-GC

That's what I figured is that it was cut too much and I was being scammed

 

[Stephy]

That's a really low dose for xr. Normal to not feel much.

If you've never felt a real opioid high....probably best to stop before you open that door because a very large percentage of people go through years of misery or death after their real hit and falling in love with opioids.

This is a significant chance to ruin your life.

Is the 90 mme they talk about not really enough to get a opiod high? I think my metabolism with that cYd what ever it is gene makes me an ultra metabolizer and my body never gets drug blood syrup levels correct to get a high from the stuff., but that's just my web MD license. I could probably am wrong

 

[LucidSDreamr]

Is the 90 mme they talk about not really enough to get a opiod high? I think my metabolism with that cYd what ever it is gene makes me an ultra metabolizer and my body never gets drug blood syrup levels correct to get a high from the stuff., but that's just my web MD license. I could probably am wrong

Is the 90 mme they talk about not really enough to get a opiod high? I think my metabolism with that cYd what ever it is gene makes me an ultra metabolizer and my body never gets drug blood syrup levels correct to get a high from the stuff., but that's just my web MD license. I could probably am wrong

To someone without opioid dependency 30 mg instant release should feel something. 90 would be too much for such a person.

For extended release it can be dangerous to use recreationally if you redose before the initial dose peaks. Or even mixing two doses on the same day.
They really aren't the best for getting high. I guess you know you need more than 30 xr...so trying 40 or 45 should be safe as far as overdose if no other drugs like alcohol are involved.

There are some people that just think the opioid high is kind of underwhelming and it is to be honest. I've heard this from people and even my first times with pills I didn't think that much of it.

It's kind of an aquired tasted but once you get the taste you're really fucked. Life will be ruined.


When you are a dopesick addict then get a good hit it feels great. But that's just because you felt so shitty to start with.

 

[Stephy]

To someone without opioid dependency 30 mg instant release should feel something. 90 would be too much for such a person.

For extended release it can be dangerous to use recreationally if you redose before the initial dose peaks. Or even mixing two doses on the same day.
They really aren't the best for getting high. I guess you know you need more than 30 xr...so trying 40 or 45 should be safe as far as overdose if no other drugs like alcohol are involved.

There are some people that just think the opioid high is kind of underwhelming and it is to be honest. I've heard this from people and even my first times with pills I didn't think that much of it.

It's kind of an aquired tasted but once you get the taste you're really fucked. Life will be ruined.


When you are a dopesick addict then get a good hit it feels great. But that's just because you felt so shitty to start with.

My script was originally written 60mg xr every 12 hours twice a day but I was running my script because it seemed like it was always wearing off at the 5,6,7 hour mark....I could set my watch to it. You see I set a timer everytime I took my meds to make sure I didn't take the next dose too soon which is how I know it wore off too fast. I've been using a timer for years doing this. The last time I was on morphine... sometimes I rotate through meds...I also noticed it worked better with half the dose more often than the higher dose less often. So I got my doctor to prescribe 30mg xr every 6 hours and it seems to work WAY better. I also have more stable highs and lows without getting sleepy on the highs and being in immense pain on the lows. I've NEVER felt a buzz or euphoria on morphine not even years before I started opiods when my mother in law gave me 30mg xr morphine pills. That really supports my theory that I'm a ultra metabolizer associated with that cyP6 or something gene...I can't exactly remember how to spell it

 

[LucidSDreamr]

My script was originally written 60mg xr every 12 hours twice a day but I was running my script because it seemed like it was always wearing off at the 5,6,7 hour mark....I could set my watch to it. You see I set a timer everytime I took my meds to make sure I didn't take the next dose too soon which is how I know it wore off too fast. I've been using a timer for years doing this. The last time I was on morphine... sometimes I rotate through meds...I also noticed it worked better with half the dose more often than the higher dose less often. So I got my doctor to prescribe 30mg xr every 6 hours and it seems to work WAY better. I also have more stable highs and lows without getting sleepy on the highs and being in immense pain on the lows. I've NEVER felt a buzz or euphoria on morphine not even years before I started opiods when my mother in law gave me 30mg xr morphine pills. That really supports my theory that I'm a ultra metabolizer associated with that cyP6 or something gene...I can't exactly remember how to spell it

Oh I'm sure myself could put you on to the right opioid and right route of administration to make you enjoy the "recreational" feeling opioids can give a person.

Even if you are a poor metabolizer opioids release dopamine which is going to make any human or animal feel good if done right

I'm against this notion in medicine that some people are capable of not "liking" drugs like morphine or cocaine or whatever. Some people just have a better judgment system or where the high is less important to them than the consequences and they don't become an addict.

Its sounds like you know what a withdrawal feels like if you've been taking all that prescribed and stop for a few days. The opiate high can be nothing more than feel normal after dosing in withdrawal.

 

[plumbus-nine]

Even if you are a poor metabolizer opioids release dopamine which is going to make any human or animal feel good if done right

Acutely, yes. I'm not completely sure of this but I suspect that long term opioid use might actually lower the overall dopaminergic activity compared to sober. Like long-term SSRI use can cause depression, opioids can cause hyperalgesia or depression also.

 

[LucidSDreamr]

Acutely, yes. I'm not completely sure of this but I suspect that long term opioid use might actually lower the overall dopaminergic activity compared to sober. Like long-term SSRI use can cause depression, opioids can cause hyperalgesia or depression also.

For sure, but they always release some dopamine when taken relative to what your current state is. But you almost feel high when you get clean because you get back just as much dopamine as your burnt out addiction would give you.

 

[neversickanymore]

I got no effect from oxymorphone. Went from oxycodone to oxymorphone and went into acute withdrawal very rapidly. When I contacted the pain specialist they thought I was trying to scam them even though I offered to bring the remaining script in.. I told them it was like taking a sugar pill. This was years ago but they threw me out and refused to see me again.

Morphine does very little and oxymorphone doesn’t do anything at all to me.

 

[G_Chem]

My first time trying morphine I took 30mg, nothing. 50mg, a little. 100mg and got a mild effect.

Then trying oxycodone 40mg was way too much. My second time with 20mg was still too much. Early on I could take 10-15mg and be feeling real nice.

-GC

 

[bookshelf1]

I got no effect from oxymorphone. Went from oxycodone to oxymorphone and went into acute withdrawal very rapidly. When I contacted the pain specialist they thought I was trying to scam them even though I offered to bring the remaining script in.. I told them it was like taking a sugar pill. This was years ago but they threw me out and refused to see me again.

Morphine does very little and oxymorphone doesn’t do anything at all to me.

uuuuh....how inhumane they can be....
didn't you object to them and challenge them by doing a discussion?maybe you could convince them by saying i accept subsequent of my decision just give me that.

I wish I could stop taking them, but I hurt so bad I can't And I don't even get real good pain From them it just makes the pain a little more tolerable.

can i ask what is your pain about?what cause it has?
personally i got opirage two times last year when i was too angry of some people.i guess if you get angry and use opioid same time,there will be a high chance of getting opioid rage.
try to read psychological books about how to overcome anger or go to a psychologist and ask for help.
i know some methods to eliminate anger,if you want i can teach you some.
for example think about that those people who made you angry they have many problems in their life as well.even if you don't know what problem they have try to compare their life with other similar people and guess how miserable they are.so you can get some sympathy with them and forget about anger.

 

[neversickanymore]

^ nahh i just ate shit for three days. Ended up at at another place. I was on 80 mg oxys at the time so I was pretty miserable. The new guy was pretty liberal so when the switched formulas on the oxy I went to 80 mg methadone and 260 mg Roxy. Now I’m two months away from a decade opiate free as I successfully treated my pain. All my love to those still suffering!!

 

[xtcgrrrl]

Oo-er, look at me, getting all poetic on a Saturday morning. What a wanker I am.

It was a nice turn of phrase, I liked it

 

[LucidSDreamr]

^ nahh i just ate shit for three days. Ended up at at another place. I was on 80 mg oxys at the time so I was pretty miserable. The new guy was pretty liberal so when the switched formulas on the oxy I went to 80 mg methadone and 260 mg Roxy. Now I’m two months away from a decade opiate free as I successfully treated my pain. All my love to those still suffering!!

Just having gone through it doesn't it terrify you to grow old in a country where pain management is basically illegal now? Like I want to uproot my entire life and leave the US because it's so terrifying to get hurt or die slowly here.

It's sad to know that fentanyl everywhere on the street is actually comforting to know its there for me when I need it one day. Becsuse unless it's an instant death we all will need it