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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

Anyone with experience with loperamide tapers?

BigG

BigG

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Hi folks, as you know i had terrible withdrawls from my opiate meds stopping last years and all was relaitively good until a few weeks back when i was given opiates for surgery. I just cant pbysically and mentally go through this shit again and so have been looking at a lope taper. I bought some otc lope the other day and it took nearly all my wds away. I was therefore considering doing a short lope taper. However ive read that if stopped ct them lope can be as bad as methadone in the duration of the wds. Maybe just a short taper will be ok.

Im off to see a different doctor today to ask for help (wont mention the lope though) but with all the massive arguements on my record from my previous doctors on my file im not hopeful of any help whatsoever.

Im sick of life at the minute. Im off worl on the sick as well and its killing me....
 
I'm pretty sure Sprout has mentioned this before Englandz. I'd ask him, if he doesn't chime in soon that is :)
 
Last spring, when I had kicked my heavy alcohol habit a few months earlier and I temporarily didn't have any connections to get real drugs, I tried to get high on mega-doses of loperamide a few times... The doses I took daily were anything from 64mg to 128mg, and I'd compare the high I got from 64mg to about 100mg of codeine. My loperamide binges lasted 3-7 days, and the "high" wasn't as pleasant as with other opioids, and after the binges I had a "lope hangover" that lasted for at least 3 days and was very unpleasant. If you took a 128mg dose today, you would still be fucked up in an unpleasant way tomorrow and the day after that and wouldn't be in the condition to go to work.

The point is, using large doses of lope even for a short period of time made me feel like shit for some days afterwards. I've never had a real physical dependence on opioids, but if I had such a habit and I'd have to taper down, I'd rather use poppy pod tea which is almost as long-acting as lope and doesn't make you unable to take a shit for a week. Also, large doses of loperamide can cause potentially dangerous cardiac arrhythmias in some people.

You could also use something like gabapentin or Lyrica for the opiate WD if you can obtain them.
 
What dose was sufficient to remove your WD's, G?

Lope is incredibly effective if used responsibly but has some worrisome aspects that rear their head early on.
 
Sprout said:
What dose was sufficient to remove your WD's, G?

Lope is incredibly effective if used responsibly but has some worrisome aspects that rear their head early on.
Click to expand...

Im still experimenting on what the minimum dose to completely removed my wds will be. I started off on 60mg which completely removed everything and am currently experimenting between 12-36mg so i can find the lowest dose possible to make it tollerable. Thing is that lope aint cheap....even the supermarket generic brands.. I tried ordering some off amazon which were insanely cbeap but it came up blank the end as appareny they dondt export to the UK (nb. Im not looking for sources). I usually dirink a 1.5.litre of tonic water a day with them too.

Ivr read the other forums which as a complete mess of Americans arguring with each othedr aboit whetger lope even works and if i hear the phrase. "Doent cross the blood brain barrier at all" or "i hear lope has just the tiniest bit of oxy in it" ......ill scream. There is no constructive advice over there just veey ignorant people and some oralsort of pissing contest to see whk can take the most 400mg being the highest i saw but i didnt read it all.

Hope someone can help. I aim on taking 12 mg today and see hiw i feel....
 
Last edited:
englandgz74 said:
Im still experimenting on what the minimum dose to completely removed my wds will be. I started off on 60mg which completely removed everything and am currently experimenting between 12-36mg so i can find the lowest dose possible to make it tollerable. Thing is that lope aint cheap....even the supermarket generic brands.. I tried ordering some off amazon which were insanely cbeap but it came up blank the end as appareny they dondt export to the UK (nb. Im not looking for sources). I usually dirink a 1.5.litre of tonic water a day with them too.

Ivr read the other forums which as a complete mess of Americans arguring with each othedr aboit whetger lope even works and if i hear the phrase. "Doent cross the blood brain barrier at all" or "i hear lope has just the tiniest bit of oxy in it" ......ill scream. There is no constructive advice over there just veey ignorant people and some oralsort of pissing contest to see whk can take the most 400mg being the highest i saw but i didnt read it all.

Hope someone can help. I aim on taking 12 mg today and see hiw i feel....
Click to expand...

There is an awful lot of shit to wade through with regards to Loperamide efficacy. it may be completely shocking to you but 90% of those who lambaste it turn out to have never actually tried it... on a forum? Never!

Loperamide does have a remarkably poor entrance rate into central systems, the average amount that penetrates the endothelial membrane to the astrocyte layer and beyond relative to circulating plasma is 0.061 (Table 3 of this paper) so the doses required to elicit local vs. systemic effects are massively variable.
 
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