This one is particularly heartbreaking and tragic to me because they were so young, and had been abusing drugs for such a short amount of time..
It's one thing if you've been using for decades, have ran out of veins, and decide to inject drugs cooked with dirty puddle water and end up kicking the bucket. Another if you're fresh out of highschool, blithely doing what your friends are doing, and happen to have not known any better.
So I am going to post my case study of myself here and in response to your post regarding endocarditis. I have had it. Twice.
My first case was in the BMJ and required open heart surgery. I'll get to the specifics but other than a lot of heroin long before it happened and sub at least more than six months before it happened (IV) can show you how long it can take to build up. Plus I was a clean shooter ever since I got an abscess in the back of my knee from scraping God knows what while on meth and trying to slam it. I legit it alone and it eventually burst while I was sleeping, after weeks of ECRUCIATING pain, and since then I was always sterile for the most part tho I did reuse a bit much, but would clean with alcohol or chlorohexadrine any time I did.
So; I am a male, 23-26 (from first to second case of endo) and weigh about 150 give or take, never been above 165 and that was after an inpatient treatment where I couldn't hardly leave the grounds. Healthy for me is 150-160.
I have a history of childhood epilepsy and mental health issues. Epilepsy has passed, though I have PTSD, GAD, OCD (clinically diagnosed) and some nerve damage. No genetic issues other than teeth problems, which is actually WAY more important than you think.
Ok so I'll give a brief outline of use six to twelve months before each case, the first being in 2012. At this time I had been injecting buperenorphine three to four times a day for quite some time, then once employed and seeing my future sons mother I started only using sublingually, about two to three 1-2 mg pieces a day. This dosage could vary a lot, and during this six month once I stopped objecting regularly I used other pills and such. Amphetamines once, oral/nasal and mushrooms and more all oral or nasal. Two exceptions were a shot of heroin, new needle and prepared very sterily.
The only other incidence was about four or five months before this, around the time of one of the heroin injections, I also tried injecting psilocybin. This was while very intoxicated and basically on a dare; it was done sterily and the endocarditis I got was not fungal or anything. Plus it was some time before.
So, the three to four months leading up to my getting sick was uneventful as my fiancé was pregnant. If I shot at all in the months leading up other than what I mentioned then I don't remember doing so, but by this time I would get brand new tools and such and be very sterile just because I had the means to. (When I was young I shot things scraped out of the inside of a dirty microwave... Yeah, I'll come back to that)
One day, I was at work, came down with a fever. Didn't feel very bad but it was enough to notice and take my temp. Almost 102. So I leave, and proceed to pass the fuck out as soon as I get home.
The rest on out is hazy, but I have context from relatives and my ex.
When I woke up, my mouth was so dry and chapped I could hardly talk. I was completely delirious and was spitting out the ibuprofen my fiancé was trying to give me. At one point I pulled down my pants and tried to sit in my freezer. Funny, except I was dying.
Eventually my mother came (with DayQuil and freeze pops... She always thinks I'm overreacting) and instantly realizes things are wry very bad. Paramedics come, and ask me where I am at et al questions like that. I answer correctly and they try to tell my mom and Fiance its drugs like crack or something and they wont take me. My mother says no, he is just intelligent normally so this sort of thing affects him differently. (I think I was so gone I didn't wanna go to the hospital because I thought I would be fine at home with rest... I get that way only when very sick) they ask again where I am, not two seconds after the first time, and I give them a totally different CITY than the first time, another one near by.
So they take me to the hospital to begin the most ridiculous, confusing and insane 2-3 weeks of my life.
Basically they couldn't figure out what was wrong, and while they were trying to figure it out, I had two TIA (transischemic attacks) which are like strokes with no permanent damage. I remember one that made me delusional and hallucinate that I was on the ceiling and the hospital was from the 1920s. Very scary shit. It wasn't for a couple days that I even started to come to normal, and have my fever down, and they still didn't know what it was; from West Nile to Meningitis to all sorts of shit, comin in with the hazmat suits and everything.
The most glaring symptom other than my hallucinations and delusions (Mom, why is the guy from Pawn Stars on a Pizza Hut commercial working for them...?) were these dots, all over my skin. Especially my limbs, and the closer to my fingers and toes, the more red dots. This is what they took pics of for British Medical, and they fucking HURT! I have never been in more, and by more I mean tangible, mathematical amount, of pain before. Every inch of me hurt beyond description, just a dull feeling like my blood was made of cement, and muscles were never supposed to be moves, like solid bone.
(Yes, when they pumped me full of waaaaay too much narcan during an OD when I was fifteen, that was the worst feeling I believe the human body can feel. But when I had endocarditis with those embolisms, that was a large sum of extreme pain over every once of my body. I pissed myself once or twice because I couldn't move to do so)
They were umbilicals. All of them. Blood clots, thousands that could have gone to my brain at any moment and cause a stroke (which they half did) or aneurysm or a million other things. If they kept I could have lost limbs and who knows what else. All this while they still can't even figure out what it is, and I am still slipping in and out of sanity, though they don't usually notice. (Even when I was totally dilution all thinking my bed was on the wall I didn't make too big offs deal out of it. I am a pretty intelligent guy and don't like to make a fuss, so I can handle most of that stuff and realize it's not right, which I guess many cant? Plus why bother lol, it's not like meth psychosis... *shivers*)
Then they do a TEE (trans esophageal echo) which SUCK when you have opiate tolerance and sub probably in my system, since the fent they loaded my veins with didn't work and the midazolam I either had a tolerance or they skipped cuz of my kpins. Even with the meds on point it's not fun; they spray this shit that taste like bananas and battery acid down your throat (some kind of cephacain? Can't remember which it is) as a topical analgesic numbing agent and shove a tube down your throat to pic your heart. Works much better than a normal echo.
And voila.
1.7 inches vegetation on mitral valve, 0.7 on tricuspid. (Sorry if sp is off)
Short version of this next story is they rush me to Lyola Hospital in Chicago and decide for surgery or not, and out in a PIC line cuz my veins are shit, then decide to send me off with the PIC and a shit load of IV antibiotics.
Four weeks go by and I come down with a fever. During those four weeks, mind you, I had to haveh Is thing dangling out of my arm with a fanny pack on filled with anti biotic a that made me itch, smell, feel, and look like a walking yeast infection. I had to wrap it with cling wrap to shower, pump it with saline etc.
I was able to use the PIC for my sub, which I never micron filter, which is dumb, don't do it. I don't think it contributed much to the first endocarditis case as the only thing it MAY have done is made the vein walls rougher and easier to catch bacteria to build up, but it WAS the IV use of ANYTHING that made it happen, and it can build up for a long time and only takes on little piece of staph getting stuck on your heart wall.
(Just not really sub in PARTICULAR - meaning more than any other IV drug - would be a culprit for endocarditis - sub IV DOES gives you shit veins, hardened veins, and no rush. Only time it may be justified is with a micron and even then try for only when you are sick as need quick relief. If you ware broke and low on sub micron filter and skin pop - same BA and last longer)
So anyway, I get a fever after four weeks of antibiotic treatment with only a day or two left, and I got it the ER and they tell me it's a systemic Candida infection. So now I am fungally septic after getting done with infectiously septic but still have a mass of infection and damage in my heart, as we find out the day before i was going to leave after the candida was gone.
0.2 on tricuspid and 80% regurgitation on mitral which means 80% is going backwards. Oh, and I have what they thought was an abcess on my heart wall.
So I get rushed back to Loyola (in an ambulance; state insurance so no copter ride, plus I was stable, but it was a trip) in Chicago and they buzz saw my chest open (seriously, it's like a table saw) that night, put me on insane amounts of dilaudid ( which once they went to oral I started just putting in my PIC since they didn't know how high my tolerance was and I didn't have/couldn't take sub) and it was hell. The abcess on my heart was just a perforation they repaired, and they managed to repair my mitral valve with a polyurethane ring (may have been another plastic) so I don't have a full valve replacement, thank shit because I am considered "significantly disabled" by certain workers advocacy groups even now. I don't have to take any warfarin or anything for it, just have to be cautious.
My son was born 7 days later. I had to be going to infusions during the labor, not to mention infusing dilaudid just so I could be there. It's all a blur.
All in all it was disgusting and incredibly painful. I have typed enough so I won't go into the second time I got it that wasn't as bad but still terrifying. Once you get endocarditis once it is way way easier to get it again; just remember I was always generally clean while IVing after my abcess, and this was years and years later, and I still got it, so I wasn't clean enough. They say I may have had a genetical silent murmur that contributed but eh. It's just luck, a slip up on sterility, and the length of time I have been IVing and how often a day, all combined.
I'll re edit mistakes and what not later on down the line and post my second case sometimes, maybe even my abcess crap if people care lol. Thanks for reading and please take heed.
Stay cool, and stay clean: in whichever way you need to.
