RCs Methiopropamine and 5-HTP?

[PandaGun]

Hi there,
I was wondering if the combination would cause a mild a serotenergic rush?

Many thanks!

 

[Hodor]

Methiopropamine is a noradrenaline-dopamine reuptake inhibitor without significant serotonergic activity, so no.

 

[Anamo7tram]

Methiopropamine is a noradrenaline-dopamine reuptake inhibitor without significant serotonergic activity, so no.

What he said.

Also, MPA is a primarily a release agent, Its structure is very similar to methamphatmine.

 

[Hodor]

What he said.

Also, MPA is a primarily a release agent, Its structure is very similar to methamphatmine.

That's what I initially thought too, but Wikipedia specifically points out that it is, surprisingly enough, *not* a functional analog of methamphetamine, by which I assume they are referring to the fact that it actually seems to function primarily as a reuptake inhibitor rather than a releasing agent.

https://en.wikipedia.org/wiki/Methiopropamine#Pharmacology

Of course that could be some Wikipedia editor misinterpreting the literature. Probably wouldn't be the first time. Might have to look into this later.

 

[Anamo7tram]

It seems as if the study is screening reuptake inhibition without regard for release.
So Methamphatmine being also a reuptake inhibitor, would carry a similar statement.

 

[DrGreenthumb]

What he said.

Also, MPA is a primarily a release agent, Its structure is very similar to methamphatmine.

The effects of methiopropamine make pseudoephedrine look good, I guess that is what is meant by not a functional analog.

5htp is just as poor.

So, OP, the answer is no, you will not get high at all from this combination, you'll just get a high pulse rate.

 

[Anamo7tram]

The effects of methiopropamine make pseudoephedrine look good, I guess that is what is meant by not a functional analog.

5htp is just as poor.

So, OP, the answer is no, you will not get high at all from this combination, you'll just get a high pulse rate.

I don't know what your talking about.

You absolutely could get high on MPA.

 

[DrGreenthumb]

Maybe you can, honestly I could get higher off a couple of sudafed, mpa just gives me physical effects like vasoconstriction, blood pressure & pulse rate.

Get some proper drugs, it's not at all like methamphetamine, that sulphur makes it shit.