Mental Health Coming off Invega Sustenna (paliperidone)

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Yeah man I don't do much either. I basically dwell on it all day. I mean it's hard not too the feeling is so horrible and intense. I just sit around and dip tobacco all day. It's sucks the one thing I hate about it the most is the boredom. Nothing is even alittle bit fun and when your doing something to get your mind off of it in the back of your mind your still thinking about it. It's in your head 24/7 that's what sucks. Time goes by so so slow man
 
Hey nathan, i totally feel you man. The boredom is so strong. It's like no matter what i do, whether it used to be fun, like swimming or playing baseball, its totally boring now and no fun. I hate to say it bro but i think were gonna take longer to recover than most because of the big ass loading dose and the 156mg dose. I wish i knew more to tell you but right now i dont. Life is gonna be hard for a while. Anyways i will ask you this. When you first got the injection did you have strange spinning feeling in your head? My head spun so bad i thought i was going to die. It got better after two days and was just mild spins but it was so bad that i couldnt even drive my car.
 
Hello paranoid android
I have not depression, Bipolar Disorder, Schizophrenia.
I was injecting through false infomartion hospitalized.(family false information about me long story)
I think that's Risperdal remained in my brain or my brain does not work anymore.
I have next week an appointment with dr,
I will scan my brain. I am so sad .but thank you write Paranoid Android

Damn that sucks why the fuck would they give Risperdal to anyone that didn't have Bipolar or Schizophrenia or some other psychosis? That is just fucking retarded. Granted i know a guy who argued with his shrink and ended up[ being tackled by security for no reason and instead of giving him a shot of a decent short acting anti-psychotic like say Zyprexa they shot him up with Clopixol which is a old typical anti-psychotic that many people say makes Haldol look good. They gave him the injection that lasts 3 days along with a shot of Lorazepam so he spent 3 days drooling in the corner of a psych ward. Why the fuck they use drugs like that when Zyprexa, Risperdal or even Thorazine aka good ol Largactil would be a better and far less unpleasant option is beyond me. During a bout of severe dopesickness i stupidly IVed 25mg's of Largactil from a vial in had because i was so sick and just wanted to stop the puking and knock myself out. Chlorpromazine is supposed to be given IM or if the person is experiencing severe nausea and vomiting through a slow drip as a injection from a syringe will possibly fuck your veins. It worked but i got some of the worst hypotention i have ever had in my fucking life. I couldn't stand up without falling down for the better part of the day. Oddly enough i find oral Largactil to be one of the more tolerable anti-psychotics and i can take it during the day without feeling like a zombie all day like a high dose of Risperdal. To me it just feels like a really strong anti-histamine really and although it's not as good as Zyprexa in stopping Mania it does work pretty good for me.

As for your reaction to Risperidone i am not convinced that your current symptoms are caused by it. Your Dopamine and Serotonin receptors should have long ago returned to normal and there is no Risperidone in your system after this length of time. The symptoms you are experiencing could be caused by something else so i would wait until what your doctor says about it. I am really sorry this shit happened to you though. This is the type of shit that scares people like me away from psych wards altogether. The mere thought of going to a psych ward scares the fucking shit out of me.
 
Its unforgivable what the doctors have done to us. We're living breathing zombies. They should use antipsychotics on fucking murderers and child molestors... Not innocent human beings like us. Im sorry i babble on this thread so much. Its just all i have since ive been medicinally lobotomized. If anyone is reading this i got my test results back. I have a "low" level still left in me. 9.4 is the rating they gave me and they said that normal "therapeutic levels" are anywhere from 20 to into the hundreds. Still proves the fuckin doctor wrong. It can and does stay in the body longer than a fuckin month. Im tired of this bullshit life. Nothing seems real anymore. I wanna slit my wrist and let the tainted blood drain until theres none left.
 
Its unforgivable what the doctors have done to us. We're living breathing zombies. They should use antipsychotics on fucking murderers and child molestors... Not innocent human beings like us. Im sorry i babble on this thread so much. Its just all i have since ive been medicinally lobotomized. If anyone is reading this i got my test results back. I have a "low" level still left in me. 9.4 is the rating they gave me and they said that normal "therapeutic levels" are anywhere from 20 to into the hundreds. Still proves the fuckin doctor wrong. It can and does stay in the body longer than a fuckin month. Im tired of this bullshit life. Nothing seems real anymore. I wanna slit my wrist and let the tainted blood drain until theres none left.

It's not the drugs in question here that are the problem it is the way in which they are prescribed. If you don't have Schizophrenia, Schizoaffective disorder, some other psychotic disorder or Bipolar then you shouldn't really be taking a anti-psychotic. Although i see nothing wrong with adding some atypicals such as Quetiapine, Olanzapine or Aripiprazole to a anti-depressant if anti-depressants alone don't help your major depression. Risperidone and Paliperidone are almost never used for this purpose as they have no real anti-depressant properties like many atypicals do. I have been on anti-psychotics on and off for years at a time usually along with a mood stabilizer like Lamotrigine. I was on Seroquel for years and besides the dry mouth and some next day sedation right after waking up i can't complain about it. I was also on Risperdal at 2mg's a day for months on end but got sick of it as i don't find it great for bipolar as it does not help the depression side of things at all and doesn't help acute or long term Manic or mixed states very well compared to Olanzapine Quetiapine or even Chlorpromazine. I also find that in the doses needed to start helping Mania which is 2mg's or above are the doses in which the zombie effect starts to kick in. Though for some reason i can tolerate larger doses without feeling like a zombie when i am manic then when i am not. I have never gotten the zombie effect from any other anti-psychotic i have taken which would be Quetiapine, Olanzapine, Methotrimeprazine and Chlorpromazine. But Risperidone is a stronger D2 antagonist then these drugs for sure.

Anti-psychotics have saved my life a few times literally so saying they are all bad is a rather blanket statement as they do benefit many people including myself. I know people with Schizophrenia and bipolar disorder who managed to find the right med combo and it actually allowed them to function and not to totally miserable all the time. Sure like any psych meds there are downsides but they are not the devil they are made out to be by some on here. You could dig up horror stories about any group of psych meds really because everyone reacts differently to medication.
 
Paranoid android, since you appear to know a little more and are more familiar with neuroleptics, would you say that even at a high dose that me and nathan received, are brains are still functional and that the mesolimbic pathway unharmed? Im really scared for my brain and really need some reassurance that i will recover. I think i am slowly getting better but it may just all be in my head..- no pun intended. Lol but seriously do antipsychotics harm the mesolimbic pathway at all?
 
Paranoid android, since you appear to know a little more and are more familiar with neuroleptics, would you say that even at a high dose that me and nathan received, are brains are still functional and that the mesolimbic pathway unharmed? Im really scared for my brain and really need some reassurance that i will recover. I think i am slowly getting better but it may just all be in my head..- no pun intended. Lol but seriously do antipsychotics harm the mesolimbic pathway at all?

I am not sure if Anti-psychotics cause what you would call harm to the Mesolimbic pathway in the brain at all but all of the Anti-psychotics that act as Dopamine antagonist acts at the Mesolimbic pathway. Schizophrenia, Depression, Drug addiction and other illness all cause changes to this pathway. High doses of strong D2 antagonists such as Haldol, Pimozide, Zuclopenthixol, etc are known to increase or mimic some of the negative symptoms of Schizophrenia such as Depression, Apathy and Anhedonia. This is just one of the Dopaminic pathways that Dopamine antagonists act on and they cause Tardive Dyskinesia through their activity on the nigrostriatal pathway.

I think normal functioning returns to the person and the negative symptoms lift after stopping the anti-psychotic in just about every case but it might be worth looking into further. I don't think Risperidone is as bad as Haldol or Zuclopenthixol for causing these symptoms and i believe Risperidone's effects on the Serotonin receptors may have something to do with it. Although according to 2 studies Risperidone and most other Atypicals are no better then Perphenazine (a typical Phenothiazine class Anti-psychotic that's classified as medium potency) at treating the negative symptoms of Schizophrenia and from personal experience Risperidone can sometimes worsen feelings of depression. So i don't think i can give you a answer as to whether long term high dose use could permanently cause those symptoms. I think it's safe to say that short term low dose use shouldn't cause any lasting symptoms once the drug is stopped.
 
Ive only had two shots... Ive been searching the internet like a tweaker trying to find answers. Some people have been off them for years and still have issues. I cant imagine that two shots could have ruined me. Im so hopeless. The doctors dont know what they've done to me and others. Im in such despair.. I want to end it. I just want my libido back. I want feelings back. I want anything back.
 
is it common for anti psychotics to induce a feeling of lethargy, a lack of interest in anything and no motivation to do anything whatsoever?

i feel like im sleeping my life away, such a waste of life. everything feels like an impossible task and i dont really care about anything, have no interests or hobbies, no ambition or drive to create a life for myself.
 
So called mental illnesses are, at least in my opinion, product of an ill functioning brain filter. Usually your brain is able to filter out distractions, such as shadows (which can be seen as people, monsters etc. related to former experiences), but in cases of shizophrenia, depression etc. this system probably is to sensitive and therefor a system overflow of unnecessary information happens. Your brain shuts down, running like a snail.

In fact we don't even know a lot about the brain and how it functions. Be aware that you are a genuia pig testing medication for the best outcome. Especially antipsychochtics shut down a lot of neuronal pathways working over your neurotransmitters, such as serotonin and dopamin, leading to a "quiet" brain. Emotions can be dangerous and are therefor the tribut you have to pay, if you do not learn to accept your illness. This is the most important thing: To learn how to live a life with these conditions. For example people losing legs or arms (etc.) have to get used to their new conditions. But as you can see there are lots of people taking part in special olympics and living a meaningful life. Taking meds to function and not working on your conditions won't do the trick.

Your worst enemy is yourself. It is not somebody else hindering your progression but yourself. After fighting my depression and psychotic episodes drugfree I can finally say that I am on my back to a quality life. Find inner peace and you will be at peace. I am not sick and never was. Maybe I am a stranger walking my own path, called crazy for my worldview, but I am glad to be different. Terms such as sick or crazy are unecessary in a world full of individuals. Nobody is normal. Everybody can do it with dedication, with or without drugs.
 
Mb-909.. I too was never sick in the head. I was simply tossed into the pile of misfit toys in the hospital and given the death sentence of neuroleptic lobotomization. How can i be my own worst enemy when it is the medication causing my problems? The drug is not an extinction of me. I would never do such a thing to myself. If i wanted to cause such unending pain and suffering, i would have just blown my fucking head off. Sam05, yes its normal, as motherfucking APs cut off our my vital neurotransmitters needed for comfort and wellbeing. I too see no point in life anymore. Im getting closer to suicide everyday, im living total emptiness. My life seems that it will never be the same again. Havent had a bit of relief in over 3 months. It seems that this drug has caused permanent damage. Hopefully my brain is strong enough to repair its broken receptors once the drug leaves my system. If i could just have a meaningful orgasm my life wouldnt be pointless. I could have kids and watch them grow up into adulthood. Maybe they will be spared of such pain and misery.
 
Hi
Awesome that you got the test done. 9.4 is still high enough to cause problems considering 20 is low therapeutic. Lowest injection is 50 mg, then consider you still have 25 mg in your system. It is significant. Even small amount of drugs can cause an effect. Just think of drinking two beers if you never drink. Or rather always beeing a little tipsy...Thats what 9.4 is like.

With regards to sexual dysfunction it does get better. Im now 4.5 months and Im looking forward to 6 months where Im almost clear.

I must warn you guys. These drugs can caise permanent side effects. Its a matter of how resilient you are to drugs and for how long you took the drug. I do however believe that you can recover. Some of it is psychological, sometimes a little push is needed. Try to get excited again, as I read someone writing. Even if your only 85% recovered its way better than 10% on Sustenna.

take care
 
By the way. I read that these drugs in some ways actually work on the same parts of the brain they used to cut and destroy in an lobotomy. If thats true, then Im never taking one again.
 
Whatsup mottec, what injections did you receive? How long did you take them? Ive been bloggin on survivingantidepressants.org alot. They have a lot of helpful people on there too.
 
For the sexual dysfunction caused by Risperidone and Paliperidone has anyone here tried Bupropion aka Wellbutrin aka Zyban? I know it helps the sexual dysfunction caused bt SSRI's and SNRI's so i wonder if it could help it caused by anti-psychotics. It may also help anhedonia as it is a NDRI thus a stimulating anti-depressant and it's Dopamine reuptake inhibition could help raise the level of Dopamine in your brain if it's lower then it should be.
 
Hey paranoid, im currently taking wellbutrin and no, as long as there is invega to block the dopamine receptors, it doesnt matter what kind of dopamine releasing substance you use or how much dopamine flows, it will continue to be blocked until the invega leaves your system. Its sad but is the truth.
 
Well im going to the hospital for suicidal tendecies. Hopefully they dont fuckin shoot me up with anything this time
 
Yea im going to try and tough this out. And my problem right now is that my life is too easy. I literally do nothing all day. That definitely doesn't help my situation. Boredom is my worst enemy. I wish i could get a job, at least id have something to occup my time. Symbolicone, you said you take ritalin. How long did it take till you got better enough so that the ritalin started to work for you? Ive mentioned before that ive tried some adderall and nothing happened. Not even a little buzz. Im just curious to see how many months it took for you to start getting your receptors back. Im starting to notice that my sexual arousal might slowly be starting to come back. Idk could just be in my head though.
I have been taking ritilan for the last two months at first i noticed an improvement right away but it was small ... currently its doing a good job with the well bultrin... ive smoked marijuana and did molly everynow and then but im at the point where i dont need that stuff im just naturally happy now and it feels great... i still have a disconnect with the external world but its getting better... after hearing about that crazy dude shooting up that church i felt true emotion... like it really hit me... im about 85-90 precent back to normal.... sorry to hear you guys have to deal with this stuff.... the boredom definitely got to me when i was going through it... i had to pick up a new hobby which is reading and just looking up tuturials online about anything
 
So called mental illnesses are, at least in my opinion, product of an ill functioning brain filter. Usually your brain is able to filter out distractions, such as shadows (which can be seen as people, monsters etc. related to former experiences), but in cases of shizophrenia, depression etc. this system probably is to sensitive and therefor a system overflow of unnecessary information happens. Your brain shuts down, running like a snail.

In fact we don't even know a lot about the brain and how it functions. Be aware that you are a genuia pig testing medication for the best outcome. Especially antipsychochtics shut down a lot of neuronal pathways working over your neurotransmitters, such as serotonin and dopamin, leading to a "quiet" brain. Emotions can be dangerous and are therefor the tribut you have to pay, if you do not learn to accept your illness. This is the most important thing: To learn how to live a life with these conditions. For example people losing legs or arms (etc.) have to get used to their new conditions. But as you can see there are lots of people taking part in special olympics and living a meaningful life. Taking meds to function and not working on your conditions won't do the trick.

Your worst enemy is yourself. It is not somebody else hindering your progression but yourself. After fighting my depression and psychotic episodes drugfree I can finally say that I am on my back to a quality life. Find inner peace and you will be at peace. I am not sick and never was. Maybe I am a stranger walking my own path, called crazy for my worldview, but I am glad to be different. Terms such as sick or crazy are unecessary in a world full of individuals. Nobody is normal. Everybody can do it with dedication, with or without drugs.

If your talking about Schizophrenia the 2 leading hypothesis on what causes it is the Dopamine theory and the Serotonin theory. Both of these can be corrected by medications that work for you. Actual mental illness like Major depression, Bipolar disorder, Schizophrenia, Schizoaffective, etc have a actual physical origin as they are caused by 1 or more Monoamine neurotransmitters being out of wack and psychiatric medications work to correct this. I suffer from Bipolar disorder (either Bipolar 1 or NOS) and the meds i take for it have been a lifesaver for me literally. I take Lamotrigine as my mood stabilizer, Quetiapine to help the Mania as well as depression and irritability and Bupropion to help the depression and seasonal affective disorder i get when i need something extra for depression. I also take Clonazepam for my anxiety and it also helps the Mania i get.

I haven't seen any good real evidence on the theory the a ill functioning brain filter is the cause of any mental illness. However i have seen some evidence that the NMDA receptors might be 1 cause in mental illness.
 
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