2cb and volumetric dosing

[hellowhatwhat]

Looking for advice on volumetric dosing.I have HBR 2cb.
Wondering how much water you guys have found is needed per mg?Does it need to be heated?
What about using vodka?Will it this be easier to do and require no heating?
Will keeping it in the solution for too long effect its potency?

 

[Kapitan]

There is a tradeoff when you dissolve it in alcohol. On one hand, the alcohol will inhibit possible microbial growth. On the other hand, alcohol is fairly volatile, and evaporates easily. As such, leaving the storage container open for even a few hours can significantly increase the concentration of your drug solution. If you decide to store it in vodka, keep it in a tightly-sealed bottle.

Just about everything degrades faster in solution, but I've stored 2C-E for over a year in solution with no appreciable loss of potency.

 

[solistus]

If you are the sort who is organized and detail-oriented enough to do something like this consistently (no judgments if not - I certainly can't follow my own advice on this one, heh), one way around the volatility issue is to keep a log each time you dose, making note of starting and ending volume remaining each time. That way, you can keep track of how much solvent is lost to evaporation between doses and calculate the new higher potency of the remaining solution accurately each time. It also helps to keep a running tally of remaining mass of the active ingredient with each log entry, so you don't have to recalculate it dose by dose every time. If you want to keep the math simple, you can also just top off the solution with more ethanol/dh2o to compensate for the evap loss.

Personally, before I got a mg scale for 2C dosing, I just used about 1:1 distilled vodka to distilled water (20% abv should be sufficient to remain sterile, right?) and an airtight container that I did my best to open for as short a time as possible when retrieving a dose.

 

[hellowhatwhat]

There is a tradeoff when you dissolve it in alcohol. On one hand, the alcohol will inhibit possible microbial growth. On the other hand, alcohol is fairly volatile, and evaporates easily. As such, leaving the storage container open for even a few hours can significantly increase the concentration of your drug solution. If you decide to store it in vodka, keep it in a tightly-sealed bottle.

Just about everything degrades faster in solution, but I've stored 2C-E for over a year in solution with no appreciable loss of potency.

I was probably going to pre-measure the solution into single "serving" bottles.

 

[hellowhatwhat]

If you are the sort who is organized and detail-oriented enough to do something like this consistently (no judgments if not - I certainly can't follow my own advice on this one, heh), one way around the volatility issue is to keep a log each time you dose, making note of starting and ending volume remaining each time. That way, you can keep track of how much solvent is lost to evaporation between doses and calculate the new higher potency of the remaining solution accurately each time. It also helps to keep a running tally of remaining mass of the active ingredient with each log entry, so you don't have to recalculate it dose by dose every time. If you want to keep the math simple, you can also just top off the solution with more ethanol/dh2o to compensate for the evap loss.

Personally, before I got a mg scale for 2C dosing, I just used about 1:1 distilled vodka to distilled water (20% abv should be sufficient to remain sterile, right?) and an airtight container that I did my best to open for as short a time as possible when retrieving a dose.

I was going to make one big "batch" of it and then measure them out into single "serving" bottles of solution.Is distilled water a must?