The one time I had discernible and hardcore (in my mind) vasoconstriction, I think it was 200mg, then I re-dosed twice more with 100mg caps I had already prepared. Before and after that at 150-200mg dosed just once, I didn't feel any.
As for the effects profile, they were from all dose ranges.
I'm trying not to sully 5 MAPB, but I mean that shit was for real. I never felt vasoconstriction like that before, and the previous posters like wayyy in the beginning of this thread were spot on. I now trust BL enough to assume danger, even if there might not be for me and/or others.
Add on to that the supposedly high potential of cardiotoxicity...Umm, no thanks.

I have a family history of hypertension and I'm a somewhat heavy cig smoker, so I'd like to take care of my heart at least minimally.
Minimal it is.
My friend, the one who likes to test stuff, likes this shit though. So I can understand if people like 5 MAPB while taking it responsibly. He doesn't seem to get any negative effects from this substance.