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Tramadol

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Rufioo0

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Aug 11, 2014
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Whats up everybody! New member here that could use some advice on tramadol. For the past 4 months or so i have been taking tramadol for a knee injury i had a few years ago and was wondering if anyone has any experience with taking this pill? To me its basically my "limitless" drug. I have had some problems with depression/social anxiety for the past year and I have refused to be on any kind of medication to help it. I won't even take tylenol for a headache. Tramadol completely gets rid of any kind of anxiety or depression im having and turns me into a much more confident person and also the person im striving to become on my own. My main question is if its making me feel this way do I have some sort of chemical imbalance in my brain thats being treated when i take tramadol? Do i need to adress my problems and be on some sort of medication for depression or anxiety? Any advice would help and also any experiences people have with tramadol. Could really use some advice! Thanks
 
40 views and no advice?! Someone has to have some sort of experience with this!
 
Tramadol gets talked about a lot on this website. I've never taken it but from what I understand it's an opioid with anti-depressant qualities (in this case, SNRI characteristics, similar to a drug like Effexor I guess) That's probably what you've been experiencing.

Definitely an interesting drug. I've heard a pretty wide range of opinions on it.
 
Burnt Offerings said:
Tramadol gets talked about a lot on this website. I've never taken it but from what I understand it's an opioid with anti-depressant qualities (in this case, SNRI characteristics, similar to a drug like Effexor I guess) That's probably what you've been experiencing.

Definitely an interesting drug. I've heard a pretty wide range of opinions on it.
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Do you think that when medication acts like a anti-depressant it means there is an underlying issue in the brain that needs to be treated with an ACTUAL anti-depressant?
 
Hey Im new here too haha :)
I have been prescribed tramadol a few times for a few different injuries and while taking it discovered that its effects also ease my anxiety and depression while on them...kinda having the effect of a sort of Benzo. I had a ton of them left after healing and just continued to use them to chill out (especially if experiencing any sort of anxiety or panic attack) and they really helped me.
Tramadol has been known to be prescribed by some doctors as an unethical form of benzo to help with depression and anxiety I found out after after realizing its effects on myself. This medication seemed to have similar effects to something containing codeine which makes sense considering is actually a synthetic opiate and because of this Tramadol is considered to be "addictive" in the medical world and is treated almost as highly as a controlled drug such as Endone. If considering asking for a prescription for Tramadol as a treatment for your anxiety and depression you should be careful about the way you ask for it in order to be successful in obtaining said script.
 
Nadinelove96 said:
Hey Im new here too haha :)
I have been prescribed tramadol a few times for a few different injuries and while taking it discovered that its effects also ease my anxiety and depression while on them...kinda having the effect of a sort of Benzo. I had a ton of them left after healing and just continued to use them to chill out (especially if experiencing any sort of anxiety or panic attack) and they really helped me.
Tramadol has been known to be prescribed by some doctors as an unethical form of benzo to help with depression and anxiety I found out after after realizing its effects on myself. This medication seemed to have similar effects to something containing codeine which makes sense considering is actually a synthetic opiate and because of this Tramadol is considered to be "addictive" in the medical world and is treated almost as highly as a controlled drug such as Endone. If considering asking for a prescription for Tramadol as a treatment for your anxiety and depression you should be careful about the way you ask for it in order to be successful in obtaining said script.
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Thanks for the response. Yeah i was gonna ask how would you go about asking for a script to help with depression/anxiety? To me i feel like if I tell them thats what i want it for and it really helps me it would be stupid of them to deny me of it! Would i need to see a different doctor? I guessing my ortho wouldn't ok that..
 
if you were to go to your GP and explain that you noticed that it has been a big help with your anxiety ect then they are more than likely going to ask about any other help or treatment you are getting to make life a little easier for you in that area (seeing a psychologist/ councilor or maybe other medication) If you dont see a psychologist or anything it is likely your GP will try to refer you to one. If you do see a Psychologist you could ask them about a script and they would be more likely to orginise something for you. Dont just outright ask for tramadol, you should explain how it has helped you ect but you could also just say something about how if not tramadol then you would like to try another type of benzo... you could say this to your GP as well. You dont want to look like you are scheming for Tramadol so asking about trying something else will show that you are genuine and that you just want to feel okay and that its a struggle if you dont have something to level you out from time to time.
It is more likely for a doctor to steer you away from a drug as a temporary fix but if you have taken the steps to get long term help then Im sure you will be able to get something (even if its not Tramadol) to make things a little easier for you, but if you arent trying to help yourself out and just want drugs to make you happy all the time then its not very likely you are going to be getting a script any time soon.
at the end of it all it could end up being a head fuck to try and get something that actually really helps you but if youre willing to help yourself then people will be willing to help you out too..
 
Rufioo0 said:
Do you think that when medication acts like a anti-depressant it means there is an underlying issue in the brain that needs to be treated with an ACTUAL anti-depressant?
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id personally stay away from anti-depressants and go with therapy, much much better. SSRIs suck imo

anyway i've read about tramadol and lots of people report this uplifting feel it has to it, much like you described it, relieving depression and all that shit. i took it once but my liver sucks at metabolizing it to the main stuff (tramadol itself has little effect it's its metabolite that does the magic apparently), but i have to say it did put me in a good mood, so i guess i can kinda see what people say

depression is much complex and imo probably not just a 'chemical imbalance'... ofc if you take euphoric drugs you'll feel better

if you care, my opinion is, good for you tramadol is doin you well, just beware of addiction and seizures and you should be ok... easier said than done though. also if you're struggling with depression/anxiety, go to therapy, CBT, wtv, welcome and peace
 
I have this exact situation going on, and I've taken plenty of Tramadol before. At this point, I'm now on Morphine sulfate IR 30mg for anxiety and depression - through a loophole. I'll explain that at the end.

First of all, what Tramadol is - it's an opioid medication - not an opiate in the same way that Morphine or Fentanyl are, but it acts on the same mu-receptors that opiates do. Because it's basically, in laymen's terms, a more synthetic, milder type of opioid, it's considered to not be as strong regarding the mental high, and it's not considered as strong in its analgesic effects (pain relief). It's also considered to not have as bad of a withdrawal as a standard opiate. But, it's still an opioid, it still has to be quit using a slow taper to avoid withdrawal, and it does make most people experience a high.

To answer your question about depression and anxiety - opiates are actually some of the best medications out there for panic, anxiety, and depressed mood. HOWEVER, they're extremely addicting, a tolerance will build requiring higher and higher dosages to achieve the same result until it can't be achieved anymore, and the body will become physically dependent so that quitting the medication will be extremely painful and sickly. If though, you've tried all other anxiolytic (anti-anxiety) medications, like benzodiazepines (Xanax, Ativan, Klonopin, etc.), and you're still suffering badly, you might be a candidate for treatment with opiate or opioid medications.

Typically, if you request an opiate for anxiety, you'll be referred to a Suboxone or Methadone clinic. I don't agree with this philosophy as these drugs are as strong as heroin. If you're only using Tramadol, and it's working successfully, there's absolutely no reason on God's green earth that you would jump up to something like Methadone. It would be making a mountain out of a molehill. So basically, it comes down to this: opiates cannot be prescribed for psychiatric usages - unless, you have a physical malady or a pain syndrome. You then have to search out a doctor that acknowledges your relief of anxiety from an opiate medication and will prescribe it for that, but in conjunction with a physical pain condition - that's the loophole. They can use your pain condition as the legal reason for prescribing, even though they're treating anxiety between you and them on a one-on-one understanding. For myself, it actually was not difficult at all to get my doctor to write Morphine for my anxiety because I also have myalgia and miotitis. I simply told him that the medication is necessary for my back pain, but also for my anxiety disorder. He didn't have a problem with it.

As for a chemical imbalance... Opiates and opioids release endorphins in the brain - what makes you feel happy and good. Anyone can get a high from taking them, so just because you're experiencing something doesn't automatically mean that you have a serotonin reuptake imbalance in your brain. However, if you think you may, it's significant evidence that your suspicions might be right because you're already experiencing relief - if that makes sense...

Just remember that deciding to use opiates for anxiety is a major decision that may have very negative consequences, but also a personal decision and one you have the right to make your own choice on. Just so you know, others will probably not be fond of it, i.e. parents and friends tend not to understand and may accuse you of drug addiction - it's a personal choice you would probably want to keep to yourself or only with a few close and specific people.

I hope this helps...
 
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I'm new to posting on the site but have been reading the many posts on Tramadol and Effexor. I know there is a drug interaction with the 2 but was wondering something. I take a half of a 37.5 MG tab of Effexor in the morning for depression and anxiety and it seemed to help but then I was prescribed Tramadol for chronic pain (2 different docs). I'm not giving up the Tramadol! It helps my pain and gives me a nice mood boost the next day. Do you think its safe to take about 18 MGS of Effexor daily and one 50 MG Tramadol tab one or two times per week about 8 hours later in the day? I understand Effexor has a short half life (4 hours?) and it seems like my dosages are so small, it shouldn't cause a reaction, right?
 
lisa1706 said:
I'm new to posting on the site but have been reading the many posts on Tramadol and Effexor. I know there is a drug interaction with the 2 but was wondering something. I take a half of a 37.5 MG tab of Effexor in the morning for depression and anxiety and it seemed to help but then I was prescribed Tramadol for chronic pain (2 different docs). I'm not giving up the Tramadol! It helps my pain and gives me a nice mood boost the next day. Do you think its safe to take about 18 MGS of Effexor daily and one 50 MG Tramadol tab one or two times per week about 8 hours later in the day? I understand Effexor has a short half life (4 hours?) and it seems like my dosages are so small, it shouldn't cause a reaction, right?
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I could't find any official contraindications between those medications on any of the government's drug and pharmaceutical sites nor anything in any journals of medicine about that - you should ask your doctor though.
 
i find tramadol definately helps with mood a lot more than other opiods too. personally it's my favourite drug for stimulant come downs (well i mean id prefer to get floored railing some hydro or oxy, but that would just be a waste of good drugs). Tramadol itself is somewhat an SNRI and weak mu-opiod agonist, with its metabolite, O-desmethyltramadol, being a far stronger opiod and a much weaker SNRI, and with a much longer half life. personally i find that perfect for comedowns because the SNRI effects help glide you out of the stimulation not too abruptly then steadily decrease to more sedation, relaxation not to mention that it takes all the aches and pains away from an amphetamine crash, and all that with the fact that it'll last like 6-10 hours which is the roughest part of a speed comedown.

it's important to note that tramadol's effects vary greatly between people because the rate which it is metabolised into o-desmethyltramadol varies greatly depending on each person's ability to metabolise it. before i tried it, i always expected it to be weak hearing other peoples opinions of it, but i was suprised by it and found it incredibly enjoyable and long lasting, so im assuming my liver does a pretty good job of de-methylating it fast so anything i say from experience should be viewed with that in mind - subjectively i probably get weaker SNRI effects and much stronger opiod effects.

i'm mostly refering to the opiod effcts here, but another thing to add is personally i find when im on an opiate even though my mood is better, im always anti-social lol, mainly with stronger things like oxycodone and hydromorphone though and i don't take them regularly. when im pinned, if someone bothers me i tend to be an asshole to them lol. im sure it helps with anxiety in that you'll worry less about things, but i don't think opiods have much to offer in terms of social anxiety help. the SNRI effects completely change the situation with tramadol though, but if your looking for those effects to help with mood, there are probably better drugs out there that a psychiatrist would love to show you lmao.

I agree with what other people say though, if you're looking for something to help with mood, try therapy before taking drugs, i've never done it or taken SSRI's, but i've heard nothing but good things, especially compared to SSRI's even thought im sure SSRI's are better than nothing. i'm not too sure how opiods affect anxiety from personal experience, but at one point in my life i was taking percacets very often to make me not depressed and that didn't end very well lol, i feel like tolerance to mood related effects of opiods develops fastest of anything related to opiods.

Just another thing to add also - opiod withdrawl/tolerance isn't something to underestimate too particularly in comparison to withdrawl from stimulants (in a broad sense i mean like amphetamines/cocaine or SSRI's). With opiates i find you build up your dose as high as you want, but your body will ALWAYS get used to the subjective mental effects (not refering to analgesia which is why people chronicly take opiods, i mean the high from the drug, which im guessing is what's giving you the desired mental effects) and then on top of that it makes you so sick when you don't have it. In my experience with stimulants, i find you can always get something from a dose, although greatly diminishing with constant use, even when you build up a hefty tolerance to it. Plus stimulant withdrawl, after the aches and pains for dopamageric stimulants go away is mainly a mental thing, which i personally find easier to keep distracted from and pass.... like maybe you'll feel like killing yourself and wont want to leave the bed for a week, but atleast your not shitting yourself every 30 seconds going through 3 boxes of kleenex per hour wiping your nose, while you feel like you've got an alien in your gut thats trying to tear its way out AAAND want to kill yourself and not leave bed for a week.

anyway im just rambling now sorry just weighing in :p
 
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TheSheExperiment said:
I could't find any official contraindications between those medications on any of the government's drug and pharmaceutical sites nor anything in any journals of medicine about that - you should ask your doctor though.
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Tramadol, particularly as the prodrug itself acts as a SNRI (not particularly strong but it's there, and it definately affects it's pharmacological profile), Venlafaxine is an SNRI. No doctor would recommend taking the two together because theres always the possibility of adverse reactions. It's probably not going to do you harm to take them both, if for example you absent mindedly took your SNRI in the morning and then tramadol for pain, but personally i'd say avoid combining them, and in my opinion (im totally inexperienced with anti-depressants) you don't have much to gain.

Speaking from subjective experience, i feel like the SNRI effects of tramadol are actually more pronounced than most people would expect. when i take a good ammount i often get the eye-wiggles like from taking mdma, which im thinking means much more seratonergic neurotransmission. i think opiod agonism increases seratonergic neurotransmission through indirect routes of action also, so i would be particularly careful. i'm sure anything you have to gain from mixing them is far put off from the chance of seratonin syndrome even if its a 1 in 1000 chance.
 
Tramadol affects the Alpha-2 adrenergic receptor which can inhibit the release of insulin in the pancreas, so to what extend should we be worried about sugar consumption while on tramadol?
 
I was given this for tendon pain, but I never filled it. I had originally asked for hydrocodone and they refused to give that instead giving Tramadol. Never knew it had these affects. I figured since it was given to me instead, it was strictly for pain with no "nice" feeling
 
My doctor does not give me enough Oxy to keep on top of the pain I have owing to my medical condition. When I run out I take some Tramadol. It's better than nothing, but it makes you sick to your stomach and does not work nearly as well as Oxy. It takes the edge off of Oxy withdrawals, though. My advice: never use this med off-label. Take as little as you can to get the desired effect. It is a schmuck medication.
 
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