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Dissociatives don't work!!

dr. dissociative

Greenlighter
Joined
Feb 11, 2013
Messages
31
Hi.

This is something that I briefly alluded to in one of the Big & Dandy MXE threads a while ago now but for some reason it never occurred to me to make a formal thread about it. I am including all the relevant information that I can think of in the OP so I don't have to explain myself later, but due to the length of the post I have also summerised my questions in the final paragraphs.

I have had a fair bit of experience with dissociatives over nearly 2 years, and this has been primarily through insufflated ketamine (I have no access to vials and won't IM until I do) and methoxetamine (sublingual and insufflation generally). I have also used nitrous to a lesser extent, and had some brief experiments with diphenedine and methoxphenidine recently.

Despite my love of dissociative drugs for their effects on cognition, euphoria and amazing potentiation potential when combined with psychedelics, when I use ketamine or methoxetamine alone, or with drugs which wouldn't generally cause prominant visual effects on me (cannabis, MDMA etc.), I don't experience any closed eye visuals except from very mild and indistinct visuals at incredibly high doses, nor do I experience any abnormal open eyed hallucinations (beyond the standard non-psychedelic drunken/"things looking different" visual effects that dissociatives bring). This is the case regardless of the dose, and I have takenwell beyond the recommended dosage for a "hole"/OBE effect on numerous occasions. In all of my experiments with dissociatives (too many to count), I can only remember 3 very briefinstances of OBE (excluding combinations with psychedelic drugs), and these were generally in very high doses in combination with MDMA (which I will not count as psychedelic for my purpose here) or mephedrone and cannabis. Each of these was dreamlike in nature, and did not seem to live up to the potential that I have read these drugs have.

I do get all the other expected effects across the dosage range, such as cognitive detatchment, loss of coordination, euphoria, slurred speach, poor short term memory, limited access to long term memory on high doses (i.e. forgetting computer passwords I use everyday) and detatchment from the senses proportional to dosage (although this seems to reach a ceiling, hence I don't hole or blackout even on very high doses).

Some final bits of relevant information which may help me find an answer: I do have a bit of tolerance to dissociatives but nothing insane (I have never used daily for more than 3 around days, and have had periods of considerable abstinence since I began using). Furthermore, this is an issue that I have had since I began using this class of drugs, so there must be more going on than tolerance issues. I believe that quality of the drugs can be safely ruled out as the problem as I have used with a number of friends who have experienced the full range of expected effects, often from lower doses than myself.

TL;DR

I am wondering is whether anyone knows of any physiological reason (not tolerance, or past abuse, see above!) which could be preventing me from experiencing the full psychedelic effects which I have read that dissociatives are capable of (significant CEVs, the OBE "dissociative hole" effect)? Perhaps some unusual nuance with my NMDA system is causing this?

If so, is there anything that can be done to remedy this? Any and all relevant suggestions are welcome.

Is there anyone else out there who is in my position, or knows of someone in my position? I ask this because I have never heard of anyone experiencing such difficulties with trying to experience the full dissociative effect.

Thanks in advance for any wisdom or advice. It is highly frustrating that dissociatives are amongst my favourite recreational substances, yet from what I understand I am only scratching the surface of what they have to offer!
 
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Also, thought it might be worth mentioning that my next experiment with MXE is likely to be Wednesday or Thursday, and I have ordered some nitrous chargers. If the nitrous arrives in time, I am considering combining the two to see if this will help "kick-start" the trip. I can't find any information which suggests that this could be a dangerous combination, but let me know if I am mistaken. MXE dosage will be high (around 100mg sublingual), and I will prepare balloons in advance to avoid any miscoordinated accidents with wording the cracker.
 
thats weird. I have always had very amazing closed eye visuals with mxe, ket, and dxm. with dxm or mxe sometimes I must meditate myself into the visuals on lower doses. try that. there a lot of meditation based visualization based exercises you can do sober

I'm surprised you got nothing from mxe plus MDMA, MXE on MDMA comedown was (some people say its dangerous*disclaimer) was the most amazing visuals i've ever had. like nothing serotonergics had ever shown me. full blow dreamlike hallucinations and scenes playing out made out of glitter or cartoons.
 
I haven't mixed MXE with MDMA, but I did do MXE on the tail end of 4-FA (another serotonin releaser) and I had a bad reaction, a terrible headache, a very fuzzy and underwhelming experience, and the next day I almost passed out every time I stood up from head rushes. I strongly recommend against mixing MXE with any serotonin releasers.
 
I haven't mixed MXE with MDMA, but I did do MXE on the tail end of 4-FA (another serotonin releaser) and I had a bad reaction, a terrible headache, a very fuzzy and underwhelming experience, and the next day I almost passed out every time I stood up from head rushes. I strongly recommend against mixing MXE with any serotonin releasers.

Yep, agreed. I may have been unclear in my original post but my combinations with MDMA or mephedrone with dissociatives have always been with ketamine. Sorry about that.
 
I don't typically get a load of psychedelia with Ket, everything gets very very sparkly though!
 
How much do you take? For me it's not psychedelic until I take a hole dosage or approaching a hole. Same with MXE. High doses are where the magic is at, low or medium doses gives you looseness, dizziness and body feelings.
 
I have done up to half a gram of decent ketamine insufflated all within a few minutes in my most desperate attempt to hole and that didn't do it (although I was very dissociated in other ways). I have tried straight up or accumulative doses of MXE (which I am working with now) of 100mg, and would be highly dissociating, yet I'd be perfectly able to stumble about my flat and carry out my business as if I was (almost) sober. In fact, I did once insufflate 250mg (? can't remember exact dosage now) of ketamine, and then proceeded to have a conversation with my flatmate without telling him I had taken anything. Apparently I appeared normal except from slightly slurred speach, which he only picked up on in retrospect. I'm currently writing this on a high dose of MXE (approx. 200mg over a number of hours) and although I'm feeling very high, there is still nothing distinct with CEV. Perhaps I have some abnormal natural tolerance to NMDA antagonists? Is there any way I could check to see if this is the case?
 
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I try not to hole very often, so I usually snort 150 or less, depending on what I'm up to, where I am or whatever.

You MUST have some sort of abnormal tolerance to dissociatives, that is frigging shitload of K and MXE.
 
It is just really frustrating, because the dissociative hole sounds amazing from the descriptions and trip reports I've read and was the experience that I originally pursued in dissociative drugs. I'm starting to think I am immune to the m/k-hole for some physiological reason. I will continue to use MXE regardless, as I really do appreciate the lower-middle range effects... But I also want to be able to experience psychedelic side to this substance!!! :o

I will update my experience in conjunction with nitrous to see if that helps, then I suppose changing ROA to plugging would be the last potential barrier. After that if I have no success, I will accept that I have some physiologcal nuance which just so happens to block out what sounds like one of the most amazing drug induced experiences possible, bar possibly DMT (although I wouldn't know, maybe dissociatives are even better than DMT!?) :( RANT OVER.
 
I have done up to half a gram of decent ketamine insufflated all within a few minutes in my most desperate attempt to hole and that didn't do it (although I was very dissociated in other ways). I have tried straight up or accumulative doses of MXE (which I am working with now) of 100mg, and would be highly dissociating, yet I'd be perfectly able to stumble about my flat and carry out my business as if I was (almost) sober. In fact, I did once insufflate 250mg (? can't remember exact dosage now) of ketamine, and then proceeded to have a conversation with my flatmate without telling him I had taken anything. Apparently I appeared normal except from slightly slurred speach, which he only picked up on in retrospect. I'm currently writing this on a high dose of MXE (approx. 200mg over a number of hours) and although I'm feeling very high, there is still nothing distinct with CEV. Perhaps I have some abnormal natural tolerance to NMDA antagonists? Is there any way I could check to see if this is the case?

Do you lay down and close your eyes when you try to hole? I find that completely essential to the experience. If I have my eyes open and I'm moving around, I'll just be super dissociated.
 
Have you considered IM K? Might have better luck!

I have indeed, it is something I am very keen to try in order to sort out whether I have some sort of physiological abnormality which is causing my problem, or whether it is just a simple case of being insensitive to less efficient ROAs. However, I do not have access to vials and I am a bit wary of IMing crystal (despite having access to high quality, from a number of sources), just in case I do end up with a minor incontamination of bacteria or something in my batch which will cause muscle damage. I understand the aim of this forum is harm reduction, but please do let me know if you think I am being ridiculously overcautious or paranoid in this regard! :P
 
Do you lay down and close your eyes when you try to hole? I find that completely essential to the experience. If I have my eyes open and I'm moving around, I'll just be super dissociated.

Unfortunately, once again this doesn't seem to be the solution - I have tried high doses of dissociatives in a variety of situations ranging from a darkened room in bed with a mindfold and earplugs, to social settings with friends and I have even ended up in a completely inappropriate public situation on a sunny day on high dose MXE recently (highly embarassing to say the least!) I have often wondered whether there is something wrong with my mindset when entering the experience (ie. not relaxed enough, or even not manic/imaginative enough) but haven't had any luck experimenting with meditation or (as alluded to previously) attempting to do "normal things" like conversing with others while under the influence. (edit: I have also wondered whether I fail to experience the expected effects due to conditioning myself not to get my hopes up due to past disappointment... does this sound at all like a feesible possibility or am I getting into "thinking too deeply about it" territory?)

Thanks very much for the help guys. I have nearly 4,000 words of essay to get done for tomorrow so probably won't check back here again until all that is done. In the meantime, please keep the advice rolling if you have any and I shall report back after my next excurtion with nitrous added to the mix to see if that helps to kick-start things!

EDIT: I realise there is probably plenty of info on the net about this, but I haven't really got the time to read up on it now... if somebody could let me know what equipment is needed for plugging MXE, I will see if I can find the time to aquire it before my next experiment. Thanks!
 
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It actually works fine just putting it in a gel cap and inserting... lotion or lube helps. The even better way is to get a small oral syringe (usually at pharmacies they will give you one for free if you ask), put the MXE in a bit of water (like 1mL), stir until dissolved, suck it up into the syringe, and insert with a bit of lube. Lay on your back and raise your lower half up so the syringe in pointing at least somewhat down, or your hands and knees work too. After maybe 20 seconds take it out quick so no liquid escapes. It should be very easy to hold MXE in as it doesn't burn at all, you might not even feel it. Either way it should start to come on quickly, quicker if you use a syringe with it dissolved in water rather than dry in a gel cap (but that works very well too honestly, over half the times I have plugged (a lot of times) I used the gel cap method). Stay on your back/knees for a good minute or two to make sure it doesn't try to escape. Also, make sure you have emptied your colon first or else feces will absorb the chemical.
 
Thanks for the reply, I really do appreciate your help. I will try asking some local pharmacies tomorrow and see what happens! :)
 
No problem. :) You can get a 5 or 10mL capacity syringe that is pretty narrow, or you might be able to ask for a 1mL syringe (sometimes they ask what size, but they should have several). 1mL is not a lot of liquid but it certainly works for MXE as the dosages are low (for example I fit 70mg of 4-FA into 1mL of water quite easily). And the 1mL syringes are very thin and should be the easiest to insert.
 
mxe is a difficult beast, I've only had one or two good holes, plus a hand full of boring visuals (looking out a bus window, or worse yet, being in work!)

Ketamine, I can only get visuals if I IM it, and even then it doesn't come easily for me. I IM 65mg (1.2mg/k or 0.55mg/lb - I think, I weigh 54kg). The dose is a little low, between "heavy" and "hole" according to erowid.

If I go higher, I usually get a panic attack situation. At this dose, I have to IM about 3 times with no visuals, and then 4th and 5th hole the visuals are incredible, any more after that I can't remember the holes. It took me a long time to get K to work for me, but it was worth it. This approach works every time, without fail for me now.

I've never managed to get it down for mxe, I'm contemplating using K to break me in and then going for mxe, whether this approach will work I don't know.

On a side note, can I ask. If you lie down in the dark, with no drugs and try to visualise something, do you struggle to visualise imagery?
 
I was a very frequent user of mxe+hash back before the UK ban. I never really got any visuals from mxe in the years I used. It was lovely despite no visuals though. I just figured that these types of drugs don't give visuals for everyone. I have tried ketamine once and didn't get any visuals either.
 
Interesting... perhaps I'm not so unique in this aspect as I thought. Anyway, I have aquired my *ahem* "oral" syringe and nitrous as planned but am feeling a bit of a wreck at the moment after staying up working on a uni assignment so I'm not sure whether to trip tonight or save it for tomorrow. Either way I've treated myself to a celebratory bump just there so I'll see what kind of mood I am in later on! %)
 
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