babylonboy
Bluelighter
- Joined
- Oct 30, 2012
- Messages
- 1,410
It's my special fave. Best downer eva 

the annoyingly-wise-and-sensible swampdragon.
Oooo, that might explain things.. I have it after MDMA quite a lot. Cheers for the other combo information too, will have to give some of those a try.Trust me, if you start taking kratom on MD comedowns you get to the point where if you don't have kratom for post-peak you don't take the MD, I can't stress enough how stronger kratom feels when you take it after MDMA, like a whole level above how you normally feel it. Seriously
amanitadine said:Sammy - Kratom is a complex beast....there is a ceiling effect on the opioid aspect, I speculate due to the presence of coryantheidine, a straight MOR antagonist, and two partial agonists.....I would also wager though that as big if not bigger of a factor is the mitragynine and it's shitty affinity for the MOR compared to the 7-OH and the pseudoindoxyl, and it's adrenergic effects...most people have a threshold that they cross where they get what is known as the "wobbles", aka nystagmus, and get shaky and kinda dysphoric. For some it is 5 g, some 20 g......for me it was around 10 g of quality stuff. Used to be 15, but I guess either a) I got more sensitive to the adrenergic effects,or b) became more tolerant to the opioid effects, which can tend to mitigate nasty adrenal shit. Who knows...
Hope you're all having a great night, awesome to see SammyG on it as well, I remember you expressing interest in trying it way back, glad you finally did it, hope it's not a let down since you probably have a heavy tolerance for opiates/opiods. It's probably just best to see it as its own thing instead of a replacement for proper opiates.
I've taken two separate 10g doses and I feel good, but not really where I'd hoped to be. It's a bit like the tramadol tease, where it seems like it'll break through into real explosive euphoria then it recedes.