Opioids Ketamine as an Opiod potentator / tolerance alleviator?

[eamonshort]

Hey guys, first post.
I have been on oxycontin for 3 years [started at 16 am 19 getting prescriptions, sometimes I need them for legit pain but for the most part I abuse them]. Used to be the days were 4x5mg endone tablets would give me a good 6 hour high but that is no longer the case. To have a good high recently needed a vast combination of potentators and a 160mg mix of endone and oxycontin in both uncrushed and parachuted form. Anyway I've heard in hospitals when a patient with a high tolerance to opiods they give them a low dose ketamine infusion to decrease the tolerance, I have a gram and want to stay far away from the k-hole due to bad past experiences just wondering how much an 80kg male would take and how and when to help my high along.

 

[Amphetafiendd]

I am unsure about the effects of ketamine and opiates but a good dose for the K would be around 30mg - 40mg. I would recommend trying to dose the K first to see how you react and if it is a little bit to much without opiates then I would recommend halving the dosage if you were to try it with the opiates.

 

[sekio]

I think it depends on route of administration.

 

[eamonshort]

I think it depends on route of administration.

So it has to be given IV as it is during a hospital administered infusion?

 

[tricomb]

essentially yes, better to be safe than sorry. When combining ketamine with opioids, a little goes a very very very long way, and there's a reason why I don't use ketamine to "alleviate" opioid tolerance because it may be an NMDA antagonist, but there are other NMDA antagonists like methadone, memantine, methoxetamine, magnesium, and from experience, none of these including ketamine reduced my tolerance in any way, shape, or form. It simply caused an additive effect on the experience.

 

[frontbluntt]

I can say though that for verrrrry mild withdrawals MXE was a goddsend

 

[Hiltoniano]

^agreed and also, I use Mxe in lower, threshold level doses (20-30mg with my lowish tolerance) and it greatly enhances the high and allows me to use less opiate to a much greeter effect. Don't overdo the dissociative because it can overpower that subtle opiate euphoria.

 

[frontbluntt]

^agreed and also, I use Mxe in lower, threshold level doses (20-30mg with my lowish tolerance) and it greatly enhances the high and allows me to use less opiate to a much greeter effect. Don't overdo the dissociative because it can overpower that subtle opiate euphoria.

yeah it's a fine line, peronally I wouldn't rather mix the two.
But as stated a threshold dose of MXE can have you feeling loads better when withdrawing

 

[eamonshort]

Yeah I was planning on only bumping like 15mg or something

 

[DoctorSativa]

YES, Ketamine will work GREAT for moderate opioid high potentiation and will not only stop your tolerance but it will also decrease it. Just like how magnesium will stop speed tolerance from happening when taken nightly, low doses of ketamine will stop an opioid tolerance from building at all.

I wish more people would know these things...

EDit: it won't take very much ketamine to stop / decrease your tolerance. Probably only 20mg's or so considering your weight. It takes 50-80mgs of Ketamine for me to start to k-hole, and I'm about 80kgs as well.

Enjoy the high but it can be a very addictive combination and now that you are not going to have any tolerance and the high lasts longer it's easy to fall in love with opioid pills... heroin nearly destroyed my life. Be careful

 

[eamonshort]

Okay, thanks heaps for the info man

 

[Eva 33]

I know that my pain doctor offers IV Ketamine infusions at our local hospital. It's a pretty expensive procedure, though, so I haven't tried it. I have chronic pain, and apparently Ketamine can help alleviate chronic pain in some patients.

In the past, I had Ketamine combined with Buprenex, so K and opiates can be combined. But of course, this was done by doctors who are anesthesiologists. I guess I wouldn't try this at home.

 

[DoctorSativa]

I know that my pain doctor offers IV Ketamine infusions at our local hospital. It's a pretty expensive procedure, though, so I haven't tried it. I have chronic pain, and apparently Ketamine can help alleviate chronic pain in some patients.

In the past, I had Ketamine combined with Buprenex, so K and opiates can be combined. But of course, this was done by doctors who are anesthesiologists. I guess I wouldn't try this at home.

"Ketamine can help alleviate chronic pain in some patients" -- huh??? Of course it can, it's an animal tranquilizer. If I take 40mgs of pure ketamine crystal I can't even feel any sensations at all, I could take a knife and skin my arm and wouldn't feel a thing. They should use ketamine more in the hospital, it's much less addictive than opioid pills and sure as hell will stop any chronic pain...