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[MEGA] Synthetic Cannabinoid Discussion - Take 4

foolsgold said:
think I know of one place that sells the bay chems but the like 10g minim order
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please don't say dr, synthetic, they are a known rip off.

I doubt it is real BAY chains, only Bayer corporation has the right to produce them, and I doubt they are licensing it to spice manufacturers.

they might be making something similar.....
 
so BB-22 was great at first, but lately i've been feeling like it has some strange action on my body aside from just its cannabinoid effects. can't say i recommend it.

maybe its just psychosomatic, but it makes my whole body feel stiff. like its having an inflammatory effect instead of the usual cannabinoid anti-inflammatory effect.
 
thenightwatch said:
so BB-22 was great at first, but lately i've been feeling like it has some strange action on my body aside from just its cannabinoid effects. can't say i recommend it.

maybe its just psychosomatic, but it makes my whole body feel stiff. like its having an inflammatory effect instead of the usual cannabinoid anti-inflammatory effect.
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be careful with that one bro,

it may metabolize into 8-hydroxyquinoline, what this will do is dump water into your lungs as well as cause acidic problems in the stomach.

you could combat the acidity in the stomach homeopathicly with apple cider, however the lung hydrolysis is more problematic.

you may notice it always feels like your beer went down the wrong pipe when you smoke, this is the liquid building up.
 
jeremysdemo said:
be careful with that one bro,

it may metabolize into 8-hydroxyquinoline, what this will do is dump water into your lungs as well as cause acidic problems in the stomach.

you could combat the acidity in the stomach homeopathicly with apple cider, however the lung hydrolysis is more problematic.

you may notice it always feels like your beer went down the wrong pipe when you smoke, this is the liquid building up.
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would 8-hydroxyquinoline have that effect even at the low dosages i use? i only smoke at most 20mg a day, usually less than 10mg.
 
The complexes as well as the heterocycle itself exhibit antiseptic, disinfectant, and pesticide properties,[7][8] functioning as a transcription inhibitor.[9] Its solution in alcohol is used in liquid bandages. It once was of interest as an anti-cancer drug.[10]
 
thenightwatch said:
would 8-hydroxyquinoline have that effect even at the low dosages i use? i only smoke at most 20mg a day, usually less than 10mg.
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picture it like having a chemically induced pneumonia, the lungs slowly fill up with liquid, could take a week, 2, a month etc but eventually your bodies natural urge to cough will take over as it tries to expel the liquid.

it all depends on the general health of the subject as well, some people whom don't smoke cigarettes are often less susceptible (cigarettes already have their own acid producing chemicals). older people may be more susceptible since they are already to natural occurring pneumonia.

Also, there are several things that could be added to a smoke blend that may reduce the acidic metabolite, I've noticed deuterium being added to noids lately, a heavy molecule like that could interfere with the metabolize properties as well, some people add honey, chocolate powder, CBD, etc so not every result is going to be the same.
 
foolsgold said:
jesus christ

Oxidation of quinoline affords quinolinic acid (pyridine-2,3-dicarboxylic acid), a precursor to the herbicide sold under the name "Assert"
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well I guess users will not have any weeds growing out of their lungs!
 
foolsgold said:
no no its not that one never even heard of them its a European one
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I think I am with Help on this one, I don't think there have been any licenses to manufactured issued for patented BAYs.

I think Bayer got scared when the whole spice scare propaganda came out and put the idea in the vault, they have a long standing good reputation to consider.
 
jeremysdemo said:
picture it like having a chemically induced pneumonia, the lungs slowly fill up with liquid, could take a week, 2, a month etc but eventually your bodies natural urge to cough will take over as it tries to expel the liquid.
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hm, i don't think that 8-hydroxyquinoline is what's causing this strange feeling i get with BB-22. my doses are pretty low (this gram is gonna be spaced out over 2-3 months), and the feeling i get is an acute reaction that only lasts roughly the duration of the high.

call me an optimist, but it sounds like 8-hydroxyquinoline and its derivatives could potentially have a positive effect on lung function as long as the doses weren't too high. anti-biotic, anti-fungal, and expectorant all in one.

harm reduction, though, so yeah everyone -- be scared. =p
 
The in-depth chemistry side of this shit escapes me tbh, but I've never had similar symptoms with this noid (it's one of my favourites when blended with AKB, actually), and I've never heard of anybody getting it, but it sounds bad enough to maybe not smoke bb-25. You never know it could be some type of allergic reaction, or even a rare side effect of the drug; their just isn't enough research data to really know.

Which is pretty ironic, considering it's a "research chemical".....
 
thenightwatch said:
hm, i don't think that 8-hydroxyquinoline is what's causing this strange feeling i get with BB-22. my doses are pretty low (this gram is gonna be spaced out over 2-3 months), and the feeling i get is an acute reaction that only lasts roughly the duration of the high.

call me an optimist, but it sounds like 8-hydroxyquinoline and its derivatives could potentially have a positive effect on lung function as long as the doses weren't too high. anti-biotic, anti-fungal, and expectorant all in one.

harm reduction, though, so yeah everyone -- be scared. =p
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well yes, they are analgesics as well!

I think it has the most potential to occur with vaping since there is no other medium or substance for the noid to mix with during metabolization, that and smoking blend is at a lower does which seems to be the key with most of these, moderation and respect.

before using CBD I've had a few that lended themselves to some lung-biscuits, mostly hard brown flem, but nothing any cigarette smoker does not already experience.

it would be great if you could go into a little more detail about the acute reaction, eg. is it in the gut, kidneys, mind, respiratory etc.
 
dopemegently said:
The in-depth chemistry side of this shit escapes me tbh, but I've never had similar symptoms with this noid (it's one of my favourites when blended with AKB, actually), and I've never heard of anybody getting it, but it sounds bad enough to maybe not smoke bb-25. You never know it could be some type of allergic reaction, or even a rare side effect of the drug; their just isn't enough research data to really know.

Which is pretty ironic, considering it's a "research chemical".....
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exactly, there can also be impurities in them, some of them are pretty dangerous, for example the even chained fluoropentyl oddities.

Here is a chart that will help readers understand the structures of synth noids a little better, it's sort of a build your own noid exercise, but is missing some of the more exotic structures on the market now.


http://www.emcdda.europa.eu/topics/pods/synthetic-cannabinoids#panel2
 
jeremysdemo said:
it would be great if you could go into a little more detail about the acute reaction, eg. is it in the gut, kidneys, mind, respiratory etc.
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it only occurs sometimes, possibly also tied to caffeine consumption. it causes my muscles to feel stiff. i smoked a few times yesterday and didn't experience it. i think there is a good chance it might just be psychosomatic. if it happens again, i will make sure to detail the effects while they are still occurring so i can be more descriptive.
 
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