Break in between different rolls?

[hazard12]

It is well known that MDMA should be taken once every several weeks if not months (although most of us are guilty of not respecting this all the time). My question is, theoretically speaking of course, What would be the recommended time in between rolls of say:
6-APB
MDAI
bk-MDMA
or any other you can think of....
If you have any anecdotal data with any of these taken several weeks in a row or so please do tell.
My question comes from the fact that MDAI (and maybe 6-apb) are non-neurotoxic, although im not entirely sure if that is the main factor in spacing rolls.

 

[cyberius]

In my experience, BK MDMA every 5 days in 200mg+ doses with some redosing hasn't caused me any comedown or negative effects in 2 months.

 

[JWills20]

Neurotoxicity is not the main reason for spacing rolls, serotonin depletion is. Of course when you take MDMA, you deplete serotonin (the extent depending on dosage). With MDMA, the enzyme that creates serotonin is then blocked for what is thought to be around 2 weeks IIRC. So one month is suggested as a safety net for serotonin replenishment. I'm unsure if the other serotonin agents you considered have similar withstanding effects on serotonin synthesis. That would be the key to find out (I would google it, but i'm meant to be essay writing now and i'm procrastinating as it is...).

Either way, the serotonin system is certainly fragile so you should exercise caution when taking any serotonin-releaser.

 

[Clocktower]

There simply isn't enough data available on research chemicals to know what an appropriate break is. We can only guess.

6-APB is almost certainly neurotoxic, since it's so closely related to MDA. Should probably take extra-long breaks with it.

bk-MDMA releases less serotonin than MDMA, so it might be okay to take a little more often.

 

[jess046]

In my experience, BK MDMA every 5 days in 200mg+ doses with some redosing hasn't caused me any comedown or negative effects in 2 months.

Give it a month more and you'll notice a difference. I found I had to up my dose to around .500mg over the course of the night. The drug stilled worked but was nowhere near as fun. BK is pretty okay with a two week break.