Mescaline doseage

[halflifelover123]

I harvested approximately twelve pounds of San Pedro cactus, despined it and took the dark green skin and the pulp underneath and dried it out. then I froze it overnight to break the cell walls, and participated it in a blender, mixed with water in a crock pot and let simmer for six hours. once filtered, the resulting liquid was dark brown and very bitter. I poured this liquid into a Pyrex dish under a heat lamp until a dark brown tar remained. I emptied out twenty five capsules of Valerian root and refilled the capsules with tar, which was very sticky and quite difficult to deal with. on my first trial I melted three pills in hot water and drank with milk and noticed definite effects, but no real trip. tonight I have done the same with eight of these pills. I took five at seven p.m and another three at nine. it is ten p.m. now and I am noticing slight visual disturbances, though I am drinking wine as well. my question is this....how many of these fuckers would you more experienced San Pedro users ingest to achieve full effects. also, if I continue redosing, will tolerance get in the way, similar to LSD.....it seems mescaline is a bit of a mystery. nobody seems to know much about it, including drug interactions. there is so little information, and so much misinformation. any advice would be great..and forgive any misspellings, my autocorrect sucks ass

 

[lovepsychadelics]

Depends on the mescaline content of your cacti. San Pedro are not known to have much more than 1 % active alkaloid content and you need at least 400 mg of pure mescaline HCL to trip. Probably the whole 20 odd caps would get you where you want to go. Have a bucket handy for the massive purge, if you don't spew you have not had enough to trip. San Pedro has the weakest alkaloid content of the common mescaline containing cacti species.

 

[babylonboy]

It's not difficult to perform an A/B extraction and have nice clean mescaline hydrochloride to work with. Plenty is known about mescaline, it was the psychedelic against which all others were measured until it was usurped by LSD. It's a ring-methoxylated phenethylamine, chemically, and a 5HT2A partial agonist, pharmacologically. The threshold dose for psychedelic activity is about 250 or 300 milligrams of the hydrochloride salt, most people prefer a dose of 400 to 500 milligrams. It will be strongly potentiated by MAOIS. It's hard to say how much you need to take of your mixture, because cactus can vary widely in alkaloidal concentration, and the concentrate you've produced has all kinds of non-psychoactive gunk in it. When I worked with dry cactus, the yield of alkaloid salts was about 0.9% by weight of the starting matter.

 

[Mudshark]

It's not difficult to perform an A/B extraction and have nice clean mescaline hydrochloride to work with. Plenty is known about mescaline, it was the psychedelic against which all others were measured until it was usurped by LSD. It's a ring-methoxylated phenethylamine, chemically, and a 5HT2A partial agonist, pharmacologically. The threshold dose for psychedelic activity is about 250 or 300 milligrams of the hydrochloride salt, most people prefer a dose of 400 to 500 milligrams. It will be strongly potentiated by MAOIS. It's hard to say how much you need to take of your mixture, because cactus can vary widely in alkaloidal concentration, and the concentrate you've produced has all kinds of non-psychoactive gunk in it. When I worked with dry cactus, the yield of alkaloid salts was about 0.9% by weight of the starting matter.

^^ good advice from bb above
tar extract is horrible in the gut , difficult to estimate dose , and can cause severe purge...
much better to go a little further - A/B and xtalize - some good teks are posted at " Mycotopia " : see teks by " Phlux " and others ... [ nausea is greatly reduced with xtals ] .

 

[MagickalKat777]

[ nausea is greatly reduced with xtals ] .

LOL not so much! I have had pure mescaline HCl and I dry heaved every time I came up and all four friends I gave it to barfed. Its par for the course.

Anyway yeah, definitely do an A/B on it. San Pedro is notoriously weak.