When I was still on Buprenorphine and Alprazolam I got down on DMT via smoking and insufflation. Smoking it seemed comparable to my "clean" times using DMT. I didn't break through on even a high 100mg dose, but I did have the geometric visuals through out my entire vision. I was fully aware of being on my couch and nowhere else though. It made me even more tired than usual. Alprazolam and opioids give me a lot of energy for some reason. I was taking at the very least 4mg of Alprazolam a day too.
When I snorted the DMT, I had to go lay down pretty much immediately. I just remember lying in bed regretting what I just did. By the time the negative feelings faded away, I wanted to function with the drug, but the real effects were gone.
I use to like snorting DMT, but that experience with it, even though it was in combination with other drugs, left me not wanting to ever do it that way again. Smoking it, you'll definitely get the psychedelic effects, but it's not going to be nearly as intense without being on a benzo. Alprazolam is a rather short lived benzo as well, so I'm sure effects will vary from when you last took it and so forth. I tried it with multiple time-lines after taking Alprazolam, and regardless of the circumstance, after smoking DMT, it left me so tired and lazy like I was a teenager again after smoking cannabis all day, so even though DMT is a short-lived psychedelic, I'd not have any real plans after it, just in case you're super lazy and groggy like I was.