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  • EADD Moderators: Shambles

oxy and gbl?

^Yeah I think you're smart to be careful with this one, it really sounds like it's responsible for a lot of deaths. Annoying not to be able to but really doesn't sound worth the risk :\
 
Did GBL with subuxone this weekend, had a great time.
I think its better to have an expertised tolerance to opioids if going to do this combo!
 
Na Page it's not even a matter of being careful. It's killed MANY BLers. bignbrown (EADDer before your time) bought it with codeine and GBL. Forget about oxy. YOU. WILL. DIE.

Besides it's a messy, sloppy, sickening combo even if done with super careful dosing. Just DON'T DO IT.

[edit] Sorry OP didn't realise you'd done your reading and had already reached the same conclusion. Thank Christ! Even when you feel like the Oxy has faded take 1/3 your normal G dose. You will be surprised.

Yeah was gonna just take 1ml and give it an hour.

I could just drink.
 
1ml is quite a bit of g....i wouldn't mix gbl with any kind of other CNS depressant, benzos in particular is just as dangerous.
 
I agree with 'noooooooooooooo'
If you take enough gbl/ghb that should surely suffice?
 
I took about 1mg etizolam and 2.5ml GBL the other night.

Result: The GBL had NO EFFECT.

Do people really die from this combo or is there something else at work?

I'm sorry if it's upsetting at all, I just find myself in a disconnect with some of the warnings.
 
Looked up big'n'brown's RIP threads, can't see anything implicating GBL. Rather it seems to have been DHC and alcohol.

I'm not trying to justify dangerous behaviour here, it just seems that GBL is getting blamed for things where the evidence says otherwise :?
 
I ended up taking 1ml after a good few hours, then another 1ml a bit later. I felt fine but a lot more fucked than I thought I'd be.
I don't think I'd taken enough oxy(60mg over 3 hours and I have quite a tolerance) for me to be in that much danger. I won't be dabbling with that combo again.

Big thanx to everyone that replied to me.

This is a bit off topic, but can anyone tell me what the best antihistamine are for potentiating oxycodone?
GP gave me Loratadine but that was just for the itch.
 
Biggest warning signs EVER.... and then still proceeding to dose that GBL and even redosing an hour later =D
 
Looked up big'n'brown's RIP threads, can't see anything implicating GBL. Rather it seems to have been DHC and alcohol.

I'm not trying to justify dangerous behaviour here, it just seems that GBL is getting blamed for things where the evidence says otherwise :?

if you have a benzo tolerance, and a tolerance to gbl where you can take a 2.5ml dose in one go, then 1mg of etizolam probably is going to do very little anyway. But as your inhibitions get lowered and your self control begins to evaporate, who knows what you might end up doing accidentally?

from wikipedia

A review of the details of 194 deaths attributed to or related to GHB over a ten-year period found that most were from respiratory depression caused by interaction with alcohol or other drugs.
One publication has investigated 226 deaths attributed to GHB.[49] Of 226 deaths included, 213 suffered cardiorespiratory arrest and 13 suffered fatal accidents. Seventy-one deaths (34%) had no co-intoxicants. Postmortem blood GHB was 18–4400 mg/L (median=347) in deaths negative for co-intoxicants.

The greatest life threat due to GHB overdose (with or without other substances) is respiratory arrest.[2][11] Other relatively common causes of death due to GHB ingestion include aspiration of vomitus, positional asphyxia, and trauma sustained while intoxicated (e.g., motor vehicle accidents while driving under the influence of GHB).[citation needed] The risk of aspiration pneumonia and positional asphyxia risk can be reduced by laying the patient down in the recovery position. People are most likely to vomit as they become unconscious, and as they wake up. It is important to keep the patient/friend awake and moving, plus do not allow them to be alone as death through vomiting can easily happen. Frequently they will be in a good mood but this does not mean they are not in danger. GHB overdose is a medical emergency and immediate assessment in an emergency department is needed.

Convulsions from GHB can be treated with diazepam or lorazepam,[11] even though these are also CNS depressants they are GABAA agonists, whereas GHB is primarily a GABAB agonist, so the benzodiazepines do not worsen CNS depression as much as might be expected.[citation needed]

Because of the faster and more complete absorption of GBL relative to GHB, its dose-response curve is steeper, and overdoses of GBL tend to be more dangerous and problematic than overdoses involving only GHB or 1,4-B. Any GHB/GBL overdose is a medical emergency and should be cared for by appropriately trained personnel.
 
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My gbl tolerance is no biggie, i only dose once or twice every couple of nights at most and I've always needed at least 2.2ml, that's just my natural tolerance. Either that or my gbl is shite. Shambles tells me some people do naturally need that sort of dose, though.

I don't have much of a benzo tolerance atm either.

I don't know how to work out doses of gbl from those post-mortem ghb blood levels, but that's the kind of info i'd like to see, because it just doesn't add up for me so far.

Yes it makes complete sense that a mind-numbing dose of benzos could lead to a deadly dose of benzos and gbl, no argument there :| personally I wouldn't choose to dose gbl on top of benzos at all, as they ruin the effects of gbl.
 
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Dunno knock, that doesn't sound typical. I've never heard of benzo's cancelling out G's effects, or viceversa. Did you take them on an empty stomach?

But as your inhibitions get lowered and your self control begins to evaporate, who knows what you might end up doing accidentally?

Ahh, all them times that I've dosed and combo'd G with much-too-impaired judgement... how am I still alive :/
 
I suppose my gbl tolerance may have crept up a bit, thinking about it. Still seems weird though. Can't remember stomach contents. And as I've mentioned I regularly use etizolam to kill the annoying afterbuzz of gbl and get some sleep. Although that seems less of a problem with repeated exposure.
 
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