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MDMA after tripping on mushrooms

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SnappleCap

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Jun 29, 2013
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So last night I did some decent mushrooms and now me and a few friends are planning on doing MDMA Sunday night (moonrocks). Will I still roll hard or not really because of the trip?
 
Btw I haven't done MDMA in over 3 months and only do mushies a few times a year, the last being about a month or 2 ago
 
It should be great! Mushies and mdxx dont have much of a cross tolerance.

Stay safe, test your product, and have fun!
 
rollonsafely said:
It should be great! Mushies and mdxx dont have much of a cross tolerance.

Stay safe, test your product, and have fun!
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I wouldnt go so far as to say "they dont have much of a cross tolerance" because they do play on the same receptors. They function very differently, but play on the same receptors. Therefore mdma and mushroom are a bit cross tolerant, and to be extra safe id recommend waiting one month between the 2. Im not gonna say dont do it, as it will most likely be fine, but theres a chance of a more diminished roll.
 
^^Yep. Anyone can correct me if I'm wrong but don't mushrooms affect H2 receptors and serotonin in some way? Or is that just LSD?

You should be alright though....but if I were you I'd wait maybe a couple more days/a week.
 
LOGan1314 said:
^^Yep. Anyone can correct me if I'm wrong but don't mushrooms affect H2 receptors and serotonin in some way? Or is that just LSD?

You should be alright though....but if I were you I'd wait maybe a couple more days/a week.
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In summary (and correct me as well if im wrong) md binds to and dumps serotonin. (blocks re-uptake from the synapse) While mushrooms only bind to the receptor, doing nothing much with serotonin directly. I believe it does release a SMALL amount of serotonin though.
 
epic11 said:
I wouldnt go so far as to say "they dont have much of a cross tolerance" because they do play on the same receptors. They function very differently, but play on the same receptors. Therefore mdma and mushroom are a bit cross tolerant, and to be extra safe id recommend waiting one month between the 2. Im not gonna say dont do it, as it will most likely be fine, but theres a chance of a more diminished roll.
Click to expand...

Whats the difference between them not having much cross tolerance and them only havin a bit of tolerance? Sounds kinda like you are splitting hairs. The OP really should have no troubles if he rolls
 
Thank you all for your feedback. I've eaten a .4 of moonrocks one weekend and another .4 the next weekend and I still rolled the same (yes I know it's a lot of rocks lol) I feel like if I was able to roll with less serotonin than rolling after mushrooms should be no problem. Correct me if I'm wrong
 
there is no problem with rolling a day or 2 after using shrooms in the sense that it will reduce or nullify your MDMA experience. (ir may reduce but I bet the difference is insignificant) The info above shows that it is worse from your brain taking the 2 in quick succession and to eliminate that you should wait. but if you are taking proper breaks and not abusing you will be fine.
 
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