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25i-NBOMe and Depression

what do you describe as often? 25I is not a recreational drug to be done once a week, or really even once a month. It makes one feel pretty happy, euphoric even, and the come down is not as harsh as one has on MDMA IMO. But if you are hopeing to self medicate away depression with 25I you are going down the wrong path IMO.
 
Often enough to cause down regulation. I've begun experiments tripping twice a week. I have no euphoria associated with the high, it can certainly amplify your mood and emotions and therefore increase euphoric feelings but it's not the root of any for me.
 
I'm not scared, I've had symptoms like that in the past from overusing hallucinogens. They always have subsided within a few weeks of abstinence. I hypothesis .5 mg doses twice a week will be sufficient to cause downregulation without causing hppd/psychotic-like side effects.
 
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f33lg00d said:
I hypothesis .5 mg doses twice a week will be sufficient to cause downregulation without causing hppd/psychotic-like side effects.
Click to expand...

This compound doesn't seem to have alot of consistencies from person to person. Do you have any kind of evidence to support this hypothesis? Do you mind explaining your scientific process regarding how you plan to test this hypothesis. Please keep in mind you are one of the first people to try this, please be careful and use proper equipment (Sub-milligram scale and careful procedure) to avoid the very real possibility of overdosing.
 
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I don't have evidence yet that's what the experiments for. Of course only in regards to the dose and frequency, the principle is supported by evidence as 25i-NBOMe is a potent 5-HT2A agonizer and 5-HT2A down regulation can treat depression. That dose and frequency is just the most I'm comfortable doing right now. My scientific process is very barbaric with n=1, so take it with a grain of salt. I'm recording my dosing patterns, and my mood while tripping and not; whether I believe it's been effective on depression or just twisting my melon.
 
Dosed Tuesday, Thursday, Tuesday, purported 1 mg tabs around 4:30 pm.
(Today is day afer last dose)

Pro:
Feel alot better, sometimes I'm happy. I'll put it like this i'm a poly-drug psychological addict and today I found the latest iphone in mint condition and didn't sell it insteading making sure it would find it's owner.
Socializing more.

Con:
Bud makes a bit more anxious than usual.
Bit word jumbly.

I would describe this as an afterglow, but I'm tentative to dose again Thursday.
 
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