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MDMA HELP needed from people with scientific knowledge about this drug !

H

HYBRID

Greenlighter
Joined
Apr 10, 2013
Messages
3
Hi all
thanks for reading this post, I have a problem and I couldnt manage to find any useful answers on the internet so I thought I would ask for help here!

Basically I have taken MDMA less than 10 times in the past 5 years, I only take it on special occasions and I used to love it, best feeling ever!

My body is quite resistance to any form of chemicals so I usually have to take a bit more than others, Well everything was fine and fun until a few years ago I started having a really annoying side effect while on MDMA, I get strong rushes of cold chills every 5 seconds and also I keep falling into really extreme rushes of sadness!

One second Im happy and dancing like a lunatic, the next second I feel of far away from everybody and lonely and everything is totally meaningless I can just sit there and cry of sadness! while feeling really cold even in a very warm place. sometimes Im dancing in the club with my winter coat on and Im still cold but sweating on and off.

I just keep trying to pull myself out of the sadness as quickly as I can by going back to the dance floor, but it keeps coming back again and again and doesnt let me enjoy it at all!

I only used to get these feelings on a come down the next day, so started thinking maybe Im not taking enough. so I take more and more through out the night but it doesnt get any better, I get high. never been too high though, Im always in perfect control of my speach and everything else and can make logical decisions if required or even do some choirs.

What do you think the problem is?

I really enjoy taking MDMA once in a blue moon for a special occasion but the last few times I took it I had the same problem and I just had to do without it on those special occasions, Also I dont drink alcohol at all so its kinda boring going clubbing when you are completely sober!!!

So I havent been out partying for nearly 2 years now! and been working so hard, I feel like I can really do with a night of fun and enjoyment, but I really dont want to take it again until I figure out how to stop those 2 problems because it totally ruins the experience!

Please Please Please!

If you have scientific or experimental explanation or resolution to the above please contact me and let me know Im desperate!

Thank you so much in advanced

:?
 
i'm not sure if this thread is best suited for add. there are no scientific studies for your specific symptoms so all we could do is speculate about serotonin release in parts of the brain receptor regulation, which isn't going to help you at all.

but are you sure you have got mdma? some people have reported similar symptoms (especially the hot-and-cold thing) with 6-apb.
 
Thanks Black, ummm I dont even know what 6-abp is, Im not an expert with drugs, only have ever done MDMA or pills and weed! could you please explain a bit more.
Im sure I had MDMA, from a few different trusted sources, every one who had the same thing was fine and normal every time, just me :(
I understand what you mean, by "scientific" I just meant does any one know what happens in my brain that causes those side effects.some one might know. and maybe if some one knows they might know how to stop it, which is the whole pint of this question, how can I stop it?

Thanks for the help x
 
Be careful, and make sure that the hot/cold thing and the dissociation aren't signs from your body telling you that something is wrong, like there's not enough oxygen getting to your brain, or your overheating, or whatever. Sit down and take a break. Two of the few fatal drug overdoses I have personally known were two guys who overheated on straight MDMA, one in a club, and the other at a party.

ETA: overheated, and went into cardiopulmonary arrest
 
What you describe could be heavy SNS or peripheral stimulation as i get this all the time on meth. It is usually safe and an expected side effect. The discomfort is real but the body is reacting to the stimulation with a fight or flight response. Its natural but is not meant to feel pleasant. That however is common with normal stims.

With MDMA its possible that it might be a mild SS situation which can be described like you did but it is far more extreme and unpleasant then the above scenario.

When i was young i managed to break my brain for years on MDMA without ever experiencing anything unpleasant while on the drug itself even in very high doses. Therefore if you do experience what you decribe and it feels very unhealthy it might be an issue, but I only say that since I never had any issues myself so if you do, it might indicate a more extreme sitation then i ever had. But thats just a guess.

Generally when i get to the point of permanent gooseflesh, cold skin and red/blue/purple extremities while also sweating and feeling hot at the same time, then i know its time to exit the situation. For me when i am not sure if i am overheating or freezing due to symptoms of both cold and heat then its a clear indication that its time to stop.

Lastly with your emotional symptoms as well its indicative you are headed for long term shit. I ended up with 8 years of suffering from this. Stop before you become the next victim. If you are doing more then 200mg of MDMA per session or more then 1 session per month you are constantly depleting and possibly damaging your serotonin system without adequate time for recovery and could be headed for disaster if you keep this up for more then a a few months.
 
arctica said:
Be careful, and make sure that the hot/cold thing and the dissociation aren't signs from your body telling you that something is wrong, like there's not enough oxygen getting to your brain, or your overheating, or whatever. Sit down and take a break. Two of the few fatal drug overdoses I have personally known were two guys who overheated on straight MDMA, one in a club, and the other at a party.

ETA: overheated, and went into cardiopulmonary arrest
Click to expand...

To put it simply what you are likely experiencing is symptoms of vasoconstriction. It feels shit but could be safe but its also possible to enter dangerous territory when it gets to extreme. Especially if Serotonin focused drugs are the main source of the experience.
 
Your use sounds moderate, so if you're keeping the dosages within reason, this sounds like something psychological, like a predisposition toward a bad trip that has repeated. If it happens again, I would try to change the setting abruptly when it does. This might help break up some unhealthy associations.
...
This doesn't really fit in this forum. moving to ED...

ebola
 
There are a few theoretical explanations I could offer here.
The mostly likely being you may have a naturally high activity level of an enzyme called monoamine oxidase (MAO) - the enzyme that breaks down serotonin and dopamine. A good friend of mine gets periods of time during the night where on MDMA his mood fluctuates, not quite to the extremes you say but it fluctuates none the less.
The other explanation I would offer is you have naturally low serotonin levels.
What I would suggest is smoking a few cigarettes during the night - this is because cigarette smoke contains harmaline, a weak reversible MAO inhibitor. (little note, NEVER take a proper MAO inhibitor with MD, asking for trouble)
So usually smoking a few cigarettes (or a pack like some people I know) slows the breakdown of serotonin and dopamine in your brain.
Also, don't drink alcohol while doing MDMA. It can lessen the effects.
Hope this helps
 
Also, boosting levels of serotonin in the days before rolling could help you. You can do this by eating foods high in tryptophan - dark chocolate, chicken, pork, eggs and cottage cheese.
 
Super_Sonic said:
There are a few theoretical explanations I could offer here.
The mostly likely being you may have a naturally high activity level of an enzyme called monoamine oxidase (MAO) - the enzyme that breaks down serotonin and dopamine. A good friend of mine gets periods of time during the night where on MDMA his mood fluctuates, not quite to the extremes you say but it fluctuates none the less.
The other explanation I would offer is you have naturally low serotonin levels.
What I would suggest is smoking a few cigarettes during the night - this is because cigarette smoke contains harmaline, a weak reversible MAO inhibitor. (little note, NEVER take a proper MAO inhibitor with MD, asking for trouble)
So usually smoking a few cigarettes (or a pack like some people I know) slows the breakdown of serotonin and dopamine in your brain.
Also, don't drink alcohol while doing MDMA. It can lessen the effects.
Hope this helps
Click to expand...

On what grounds are we implicating high activity of MAO?

ebola
 
Well thanks for all the helpful messages, I used to take this probably every 6 months or even more, due to the unpleasant effects that I described I totally stopped, it has been more than 18 months now.
I NEVER drink alcohol anyway, it makes me sick.
I do smoke cigarettes all the time, including when on M but if Im in a club I smoke much less than I usually do.
I never paid any attention to see if smoking changes any of it.

Clocktower, I dont have a test kit, do you think I might have been given something other than MDMA?
What can causes these symptoms ?

I got these side effects the last 3 times I did it, I got from 3 different sources, is that possible?
 
ebola? said:
On what grounds are we implicating high activity of MAO?

ebola
Click to expand...

People's original or baseline tolerance to MDxx drugs is mostly due to high MAO activity. It's more a theoretical suggestion, the variance in MAO activity from person to person varies wildly.
 
I dont have a test kit, do you think I might have been given something other than MDMA?
Click to expand...
You don't know, and neither do I. :\ Check out test kits from Dancesafe, EZtest, Bunk Police, NIK, etc.
 
HYBRID said:
.

Clocktower, I dont have a test kit, do you think I might have been given something other than MDMA?
What can causes these symptoms ?

some people have reported similar symptoms (especially the hot-and-cold thing) with 6-apb.
Click to expand...

I got these side effects the last 3 times I did it, I got from 3 different sources, is that possible?
Click to expand...

Seems like Black answered your question about what could cause such symptoms. And as you didn't test there is no way of scientifically knowing what you have been taking.
 
te cold rush is the best thing of all mdma effects, imo. just enjoy it...you feel all that cold in your body...it's amazing. if you don't like that, drink a lot of alchool while you're rolling. but i rather don't drink more than a few beers, becuase i fucking love that cold. if you don't feel cold, than it's not real mdma. trust me.
 
the problem is your mood, your feelings, your emotion. this trouble is in your mind, in my opinion and experience, the real problem is that you aren't really happy in this period of life, my advice is to take a break and try to roll again when your life is changed. trust me i stop taking XTC for six months (i usually use it once a week or even twice per week) trust me i have more experience than you with this stuff.
 
comunque i neuroni che controllano la termoregolazione sono nell'ippocampo that means neurons that control termoregulation are in the hyppocampus...i'm a student of pharmacy
 
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