yeah doesn't sound like something I want to be snorting, hell doesn't sound like something I want to be ingesting period lol.
most pills I don't mind taking orally, but opanas seem to be 10x stronger when snorted.
anyways thanks for the info, I wouldn't mind finding out more about it.
I know plenty of people who snort them so I would like to research it more, anything you find out I would love to know.
I should quit snorting them, but the addict in me thinks otherwise.
More details:
So in general there are warnings about snorting pills, especially on a regular basis, as particles might end up in your lungs and your body can't remove them, potentially causing damage.
I will go through each ingredient for you:
Microcrystalline cellulose + colloidal silicon dioxide
The big scare about the old Opana was that they contained silicified microcrystalline cellulose (SMCC), a "patented combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD)". These Actavis Opana contain microcrystalline cellulose + colloidal silicon dioxide, so I'm thinking isn't that just the same thing? Or is the "silicified" MCC some weird process of combining the 2 ingredients in a way different from just putting them both in the same pill? I don't know...
Potential for Silicosis - One of the main worries with SMCC is the idea that it could potentially cause silicosis, which is a lung disease that may be fatal. Caused by inhalation of crystalline silica dust, silicosis causes inflammation and scarring in forms of nodular lesions in the upper lobes of the lungs. Silicosis can cause symptoms like shortness of breath (normally exacerbated by exertion), coughing (often persistent), fatigue, rapid or laboured breathing, decreased appetite, chest pains, and fever. It is often misdiagnosed as asthma, pulmonary edema (fluid in the lungs), pneumonia, or tuberculosis. People with silicosis are more likely to develop these lung diseases as well however. Silicosis symptoms can develop anywhere from weeks to many years after exposure. There is some controversy as to how high the risk of silicosis is from snorting pills, with some people being like "ZOMG never snort Opana you will die!!!" and some people being like "I think it's bullshit scaremongering". Personally I think it's somewhere in the middle. There are a number of threads on this topic, for example:
OPANA ER insuffalation and Silicosis
Titanium dioxide - Titanium dioxide, when inhaled, has been classified as a carcinogen. Studies found that powdered titanium dioxide caused respiratory tract cancer in rats exposed by inhalation. Particle deposition, impaired lung clearance, cell injury, fibrosis, mutations and cancer have also been seen in people working in environments where they inhale titanium dioxide dust. Studies have also found that titanium dioxide nanoparticles cause inflammatory response and genetic damage in mice.
Other ingredients: *I have no idea how safe these ones are for snorting*
Hypromellose - a "semisynthetic viscoelastic polymer" which gels up in water
Magnesium stearate - this is a filler in almost all pills, is not soluble in water
Yellow iron oxide - a pigment
Conclusions: I really don't think anyone knows the exact level of risk from snorting these pills. Obviously using opioids is an inherently unsafe activity to begin with, and many addicts care more about getting high or saving money than potential health risks, especially long-term health risks that don't develop immediately. It's difficult with Opana because I don't know of any safer ways to use it that get anywhere near the bioavailability. Some people say they have good results with rectal administration, but others say it's way less strong than snorting. Haven't tried it myself so don't have any personal experience to offer. I would say it's worth a try at least. Some people post methods for snorting to try to reduce how much powder ends up in your lungs, I don't really know how well this works. Sorry I can't be of more help
