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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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when i was taking 16mg/day, i'd dose 8mg sometime in the mid-morning and again at 5PM mon-fri (at the office), and i unintentionally would skip dosing 95% of the time for the entire weekend and not even notice it, til i wound up with extras at the end of each month. at 6mg or less per day though i also start to feel "yucky" after just about 24 hours, and when i was on 2-4mg/day certainly around 24 hours i'd start with the constant yawning and sometimes wanting to scratch my skin off. if i'm running low lately though my strategy is to cut next dose in half and wait at least 36 hrs, if possible, til taking again, depending how much is left.

really though i *hate* running out at all, i'd rather cut my dose in quarters for a couple weeks to last me up til my next fill, but a friend of mine will go thru their script of 16mg/day in less than a week, which just seems crazy to me, nevermind wasteful-- and to put yourself in that position month after month?? i don't understand it, but i guess that's the difference between being a bit further into recovery vs still practicing addictive behaviors (not that i don't have any, but not with sub, with amps).
 
Captain.Heroin said:
8o

Holy fuck! If I was taking that much, I'd have a bunch of problems going to sleep too!

Try taking less. If you're taking 4mg sublingually, that's not bad. But with the IV ROA, a little goes a very long way. I personally wouldn't inject more than 0.2mg at a time for severe pain.

Right now I'm using 0.08mg per shot.
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It does not feel like much of anything when injected... I mean yes, moreso than sublingual, but it is not anywhere near a shot of something else.
 
Hey I just got bup generic tablets and I have to say that it is much cleaner than.suboxone. naloxone fucking sucks, gave me headaches and made me nauseous as fuck. Especially since sub tablets are going out of stock and I.like to snort my bup gen bup is the way to go. Fuck naloxone...and generic bupre bupre is the way to go, it costed me a third of suboxone strips or pills. It is a lot cheaper, I definitely advise switching from suboxone to gen bupre

@ellula
Smaller doses are the way to go, I get more beneficial effects from 1-2mg as apposed to 8mgs. That high of dose made me feel weird, but bupre is weird, less is more and I felt happier on 1mg and I know others will back me up, look at captain heroin, he takes less than 1mg a day and he aggrees that less is more
 
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Toz said:
I live in Sweden and I have yet to hear about anyone who is on buprenorphine maintenance that doses every other day. Such a treatment would not be a viable option in my oppinion, since while it can be done, it will inevitably lead to discomfort between doses. I did this before I quit taking subutex though, went from dosing twice daily to dosing once every other day and then once every 3:rd and after that I just quit.
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I don't know exactly in which country this is practised and I'm not saying this is the main solution, it's an option just as dosing methadone twice a day (e.g. this is not available in my country, at least not officially and not on all programmes). While I can't see myself dosing every other day either now, there are papers about alternative-day dosing. I found this on the first page typing simply "every other day dosing suboxone" in Google.

I remember buprenorphine worked for me a few years ago long enough to dose it every 48hrs but I was simply afraid not to dose it in the morning. If I hadn't had to go out on weekdays, I guess I would have had no problem with alternative-day dosing then.
 
jackie jones said:
It does not feel like much of anything when injected... I mean yes, moreso than sublingual, but it is not anywhere near a shot of something else.
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I gotta agree w/ Capt' on this one anymore than a single 0.25 or maybe 0.50 (if your tolerance isnt down) is overkill -Temgesic is measured out in these doses because it has the highest potential for analgesia.
 
So i took 1-1.5mg of sub on friday and am trying to get high on some fire d right now, i heard if you take a low dose of sub it wont block it all that much?
 
tomatalli said:
So i took 1-1.5mg of sub on friday and am trying to get high on some fire d right now, i heard if you take a low dose of sub it wont block it all that much?
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That's usually true but not always the case. Have you been on suboxone consistently? Or did you just take it friday and that's it?


Usually, especially after a day.. anything less than 2mg's won't block that much. That's how it is for me at least and many people I know. If you are a person with a slower metabolism however, there could be more of it in your system than you think.
 
I have a very fast metabolism. Im skinny around 6'4 180 pounds. I dont take suboxone much probably a total of about 7-8 times over the last month i took a little on wednesday around 3mg none thursday and 1-1.5mg friday.
 
adder said:
I don't know exactly in which country this is practised and I'm not saying this is the main solution, it's an option just as dosing methadone twice a day (e.g. this is not available in my country, at least not officially and not on all programmes). While I can't see myself dosing every other day either now, there are papers about alternative-day dosing. I found this on the first page typing simply "every other day dosing suboxone" in Google.

I remember buprenorphine worked for me a few years ago long enough to dose it every 48hrs but I was simply afraid not to dose it in the morning. If I hadn't had to go out on weekdays, I guess I would have had no problem with alternative-day dosing then.
Click to expand...

I think that if someone spaced out their dose by adding an hour between dosing each day until they are dosing every 48 hours, then they can get by pretty easily after a few days of adjusting to it.

I find that the frequency in which you dose has just as much to do with withdrawals as the dose. When your body expects its next dose and doesn't get it, the withdrawals occur since your body is used to operating normally when it gets dosed at that particular time.
 
Spacing out doses over increasingly long periods is one way to taper. I find it is especially useful once the dose gets to a very small amount that does not divide down easily.
 
I feel that it simply would not be very effective to treat buprenorphine patients by giving them high dosages 3x a week. Every other day could work, but every 3rd day seems..stupid. Even when I was on a high dose of suboxone (24mg), I could feel at least 75% of the effects of my normal dose of heroin. Had I gotten used to dosing like that, I feel like I would inevitably end up picking up and relapsing. Plus, in that link that adder supplied, they claim that they make up for skipped days by tripling the dose (so if they had a patient on 8mg/day, than 24mg/3 days should suffice). This doesn't even make sense though as the half life is 36 hours, so by the 3rd day, the patient would have only 6mg of Bupe left in their system and almost certainly begining withdrawals. Perhaps my metabolism is abnormally fast, but I always felt like unless I took 16mg/day, I always had to divide my dose in half and take it in the morning and evening in order to maintain psychological comfort. Because of that reason, I think that I would honestly prefer to taper down to .5-1mg and straight up kick it from there rather than miserably waiting 72 hours to get my next dose..

Anyway, as to the question regarding whether 1-1.5mg of suboxone will block the effects of heroin...I agree with what mr.scagnattie said. Under 2mg, Bupe usually has little to zero blocking effects, even if you've been maintaining on a milligram. If its a one time thing (acute rather than chronic), you honestly should have no problem. Just be careful not to over do it with the smack.
 
Fire&Water said:
I gotta agree w/ Capt' on this one anymore than a single 0.25 or maybe 0.50 (if your tolerance isnt down) is overkill -Temgesic is measured out in these doses because it has the highest potential for analgesia.
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I tried a 2mg shot. It seems there is potential. I will try lower next time. I guess I just had a difficult time accepting that a sliver of a strip is worth injecting.
 
^its so much better though, and just think, if it was a 2mg strip, .5mg would be the same size as 2mg of the 8mg strip. I agree that buprenorphine does produce a nice feeling of well being, the trick is to just not expect too much. IMO it's like taking 10-20mg of methadone. Not overly euphoric. But a noticeable increase in mood and relaxation.
 
My last two doses I made it 28hrs and the next one 26hrs. I am definitely start to feel the sub again! There is hope you guys who are not feeling anything, dose less and less frequently. I actually feel warmth in my chest like a true opiate and I actually can't believe it. I took maybe .8mg in ethanol solution and hold it for 60-90 minutes. I start to feel effects after about 60-70min. I can't believe how much I feel it. It's like the old days. I thought my tolerance was permanently fucked for life because I was taking 2-4mg and not feeling anything and chasing that warm glow I once got. Now I got that again and I am so stoked and I think you guys can achieve the same if you are having the same issue with tolerance like I was.

I do wake up feeling sick after dosing 1mg or less because the half-life is definitely decreased. I feel the effects for 12-16hrs and then wake up very uncomfortable, irritable, depressed and my body is sore, cramping and I have to use the toilet immediately but the pay off is huge. I am so glad I started this taper. I hope to be able to dose every 36hrs soon. Also, I find that gabapentin and hydroxyzine help to potentiate the glow. I take 900mg gabapentin, .1mg clonidine right before I dose and I take 50-100mg hydroxyzine pam ten minutes after I spit out the sub-ethanol solution. I find the ethanol definitely increases the effects and makes doses of 1mg or less effective, where was normally I would need 2mg and I would still not feel this glow. So, those of you stuck in a depressed cycle chasing the warmth you once had, send yourselves into mild withdrawal and then dose 1mg or less as least often as possible.

Also a good way for me to know if it's a good time to dose is to look at my pupils. I used to dose my sub 2-4mg even when my pupils were quite small or near pinpoint which just lead to me going over the ceiling and stacking up the sub in my system. Now I wait till my pupils are a little bit dilated and I start feeling mild physical withdrawal. A lot of people say its counter-intuitive to dose like this because they say the point of sub is to not feel a high and feel normal and not feel a difference when you dose at all. Well, I don't really feel a 'high' just a warmth and a glow and I definitely feel a lot better than I did on higher doses. Also, a lot of the suboxone glow and feeling is mental. I gotta tell myself I am going to feel good before I dose now, where as before I would always say I probably won't feel this or this is taking me over the ceiling. So, thoughts do influence it so I stay positive and expect to feel good and I do for at least the first 12hrs or more. Sorry for rambling you guys but I haven't had this kind of warmth in my chest from suboxone, maybe the first couple doses but this feels even better. I had all but given up on this medication and I am so glad I got a lock-box for meds (I gave the keys to my Brother and Mother) so now I can't cheat on my taper, well technically I can cheat because they don't watch me take the sub out and I have the lock-box in my room but it just makes it more of a hassle and it makes it easier to taper. Now it's time for some breakfast, tea and cigarette. It's gonna be a good day my friends :)
 
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daveykronick said:
My last two doses I made it 28hrs and the next one 26hrs. I am definitely start to feel the sub again! There is hope you guys who are not feeling anything, dose less and less frequently. I actually feel warmth in my chest like a true opiate and I actually can't believe it. I took maybe .8mg in ethanol solution and hold it for 60-90 minutes. I start to feel effects after about 60-70min. I can't believe how much I feel it. It's like the old days. I thought my tolerance was permanently fucked for life because I was taking 2-4mg and not feeling anything and chasing that warm glow I once got. Now I got that again and I am so stoked and I think you guys can achieve the same if you are having the same issue with tolerance like I was. I do wake up feeling sick after dosing 1mg or less because the half-life is definitely decreased. I feel the effects for 12-16hrs and then wake up very uncomfortable, irritable, depressed and my body is sore, cramping and I have to use the toilet immediately but the pay off is huge. I am so glad I started this taper. I hope to be able to dose every 36hrs soon. Also, I find that gabapentin and hydroxyzine help to potentiate the glow. I take 900mg gabapentin, .1mg clonidine right before I dose and I take 50-100mg hydroxyzine pam ten minutes after I spit out the sub-ethanol solution. I find the ethanol definitely increases the effects and makes doses of 1mg or less effective, where was normally I would need 2mg and I would still not feel this glow. So, those of you stuck in a depressed cycle chasing the warmth you once had, send yourselves into mild withdrawal and then dose 1mg or less as least often as possible.
Click to expand...

If you are holding an approx' 1 mg. solution in your mouth for 60-90 minutes you are way better off plugging
(if you havent thought of it already)...the ROA is higher & you dont need more than 2 ml. of water.
 
The issue with plugging is when I wake up I have loose stools and stomach cramps, sometimes liquid shits so I am afraid it won't be as effective as it could be and or that I will have to shit once it gets in me. Also, I use ethanol-solution so it definitely potentiates it, probably as much as plugging. Another thing is I have an enlarged prostate and plugging things is very uncomfortable and not recommended. If I didn't have ethanol to put in the solution (2.5mls) I would consider it but I generally only plug drugs I can get high off of (because of how uncomfortable it is for me with my prostate) and I don't really get a high from subs although today I do feel awesome. I don't really mind holding the solution in my mouth for so long and I like the burn from the ethanol. I could be causing tissue damage from the ethanol but I am not too worried at this point. I do appreciate the advice tho and it would definitely be easier to plug if I didn't have the prostate and stomach issues.
 
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