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The Big & Dandy 25I-NBOMe Thread (3rd edition)

What [b]in your experience[/b] would be a maximum responsible buccal dose for 25I?

  • up to 500 μg

    Votes: 9 8.1%
  • up to 750 μg

    Votes: 17 15.3%
  • up to 1000 μg

    Votes: 32 28.8%
  • up to 1500 μg

    Votes: 30 27.0%
  • up to 2000 μg

    Votes: 14 12.6%
  • a dose higher than 2000 μg

    Votes: 9 8.1%

  • Total voters
    111
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I've not messed with 25i in quite a while but I am interested in how many people seem to experience little or no bodyload with this chemical. I rather liked 25i but the bodyload made it simply unbearable for me. Even at very low doses (~250ug) I always experienced many issues with muscle tension. My hands would tremor very slightly, I would experience leg cramps, and I would experience a very strong feeling to clench and release my hands.

I am curious if any others have experienced similar effects.
 
I have, and thought it was due to my method of administration. (vaporizing)

I think it's more likely that the times I sublinigually dosed, and only got a very light pea feel, like a small amount of 2cc, I simply wasn't getting a proper dose of the drug into my system, despite the mg amount in my mouth being what I would now consider drastically too much.

I've gotten body load like you describe at all active doses.

But as always with these things, ymmv.
 
Absolutely pr0digy, body load can become severe with 25I especially. Think it's a lot more adrenergic than B or C if I understand correctly activating the alpha 2 adrenoceptors and that's what causes more pronounced vasoconstriction, cold, muscle tension and tremors at 1mg and up for me. Seems to pass as you near peak suddenly warming up and the shakes disappearing, discomfort returning when into the come-down though feels different there. Not cold and trembly any more, just uncomfortable with a heaviness in the chest doesn't feel especially good for you. ROA doesn't seem much of a factor with the trials I've done, body load is similar whether blotters or nasal. What changes is the length of time it takes to get past it at peak, blotters seem to take much, much longer.
 
Hm, if i'm not mistaken alpha 2 agonism actually promotes vasodilation. Vasoconstriction probably has more to do with alpha 1 and beta activation.

Has anyone experimented taking anti hypertensive drugs like clonidine or propanolol in combo with 25I? Has this helped with vasoconstriction?
 
I am thinking about doing 25i-nbome for the 2nd time tomorrow but I am a little bit worried. When I did 1mg 1 1/2 weeks ago I got very sick the next day. Even though I mostly came down around midnight I didn't fall asleep until noon the next day. I woke up at 6:30pm with what felt like a fever and had a headache so bad I couldn't leave my bed and I could not eat at all. When I finally did eat I threw up shortly after but thankfully my headache started to go away after that. I only got 2 hours of sleep the night before dosing and not much several days before not to mention how long it too me to fall asleep. The sleep deprivation mixed with the fact phenethylamines can be hard on the body is probably why it happened. I got no negatives effects at all during the trip or on the comedown besides not being able to sleep. It wasn't until I woke up the following evening that I felt crappy.
 
Hm, if i'm not mistaken alpha 2 agonism actually promotes vasodilation. Vasoconstriction probably has more to do with alpha 1 and beta activation.

Has anyone experimented taking anti hypertensive drugs like clonidine or propanolol in combo with 25I? Has this helped with vasoconstriction?

I've taken a small dose (12.5mg) of metoprolol during 25I trips, and it seems to help. But I also don't get a lot of vasoconstriction on NBOMes anyway.
 
During my last trip on 25c i had really strong vasoconstriction (even after 3 days my legs still hurt) i was hoping that the vasoconstriction from 25i was less strong,but from what i've read on various forums it is more or less the same.
 
Can I split the blotter in 2 ? 25i-NBOME non-complexed

I have a 1200 microgram 25i non-complexed blotter. My question is, can I split it in half ? Would that be equal to half a dose? Does the substance distribute equally within the blotter?

I don't wanna take all of it at once since I've never taken it before and I do not know how I will react.

Come on... somebody must know if this works or not?
 
Last edited by a moderator:
Please don't multiple post - this won't speed up the answers, Bluelight isn't an instant chatroom so replies can take a while - it's advised to post in advance of when you're planning a trip etc. It does suck sometimes when you need a quick reply but yeah.

Yes you can split it in half - whether or not it'll actually be half the dose depends on the method used to lay the blotter, some methods result in an equal or almost equal spread across the whole piece of blotter while sometimes blotter can be laid unevenly.

PS merging your posts and then merging this into the 25I-NBOMe Big & Dandy thread now, since your question has been answered. :)
 
Tried a bit of experimentation with modifying bodyload of 25-i. Had roughly 1.5g of phenibut four-five hours before dosing. Decreased body load markedly. Almost no tremors noted from the thighs. Hands were indeed a little clenchy, and I doubt I could have rolled a cigarette for the life of me, but all in all, I was very pleased with the decrease in stimulation that phenibut afforded.

It also didn't seem to blunt psychedelic effects too much at all. I did have to redose slightly higher than I did in the previous week, but I'm marking that down to temporary tolerance increase, and not waiting for as long as I should before tripping again.
 
I've not messed with 25i in quite a while but I am interested in how many people seem to experience little or no bodyload with this chemical. I rather liked 25i but the bodyload made it simply unbearable for me. Even at very low doses (~250ug) I always experienced many issues with muscle tension. My hands would tremor very slightly, I would experience leg cramps, and I would experience a very strong feeling to clench and release my hands.

I am curious if any others have experienced similar effects.

Absolutely pr0digy, body load can become severe with 25I especially. Think it's a lot more adrenergic than B or C if I understand correctly activating the alpha 2 adrenoceptors and that's what causes more pronounced vasoconstriction, cold, muscle tension and tremors at 1mg and up for me. Seems to pass as you near peak suddenly warming up and the shakes disappearing, discomfort returning when into the come-down though feels different there. Not cold and trembly any more, just uncomfortable with a heaviness in the chest doesn't feel especially good for you. ROA doesn't seem much of a factor with the trials I've done, body load is similar whether blotters or nasal. What changes is the length of time it takes to get past it at peak, blotters seem to take much, much longer.

I get really intense shaking and shivering in my hips and thighs (usually sitting down when I'm coming up) but the sheer confusion at the peak (ego death?) makes you forget any of it and the rest of the trip is warm. That's on 1mg and I plan to trip half that from now on. The visuals on 1mg are unbelievable and make the trip very overwhelming for me.
 
For 25I bodyload, try taking a magnesium supplement, it will act as a muscle relaxant.
 
im echoing what others say about body load and vasoconstriction. i took a quarter of a 600ug tab. a certain anxiety after taking it then several hours of stimulation. (no real pschoactive effects at such a low dose) playing computer games and talking.

i passed out and woke up about 8 hours after taking it with a numb left arm and then started violently shaking which lasted about 2 hours then subsided.
 
Interesting ZN, one of the reports on Erowid suggested it tends to depleate Magnesium and potassium. ANd it could be dangerous to those who have low levels....


I eat alot of banannas and load up on dates and other sweet fruits that may have helped ease some of my effects. As I said what I felt was pretty mild at 500 ug.


excited about going for a full 1 mg but I have no plans to push it much further then that. Again my first try was last week.... so I am being smart no need to go back anytime too soon, I don't want my tolerance...... or current lack there of .... to be effected
 
Me and my friend are supposed to have some 25i-NBOMe tomorrow, and my friend started wondering, if he will have some nasty side-effects from Citalopram medication he's taking. So is it safe to take 25i-NBOMe if you are on SSRI medication?
 
Hello everyone, just registered and I wanted to post my first trip report which will also my first post. I've always been interested in psychedelics. But I had only used salvia several times until last Friday. A few weeks ago I came across with NBOMEs, did my research and bought 5 tabs 1200ug 25i (non-complexed) from a very trusted and well known vendor. Here's what happened;

Well I (187 lbs) and my friend (207 lbs)
No previous psychedelic experience. Have used mdma. Maybe I'm sensitive to nbomes, I really don't know, but I had the strongest experience of my life.

23.20 We hold the tabs (each 1 tab) on upper gums for 20min while holding the saliva the whole time.

23.40 Then we threw the tabs.Ten min later I felt a strange energy rush, not like mdma rush, more of a "storm is coming" kind a way.

00:00 We were waiting for the train (subway). As soon as I arrived there I felt my sense of depth had changed. Then I saw the big mural on the wall. It was changing rapidly in 3d, my jaw dropped open. It seemed so natural. Then I looked the other side of the subway, as I looked the far side of it, it got deeper and deeper. I felt like I was in a sci-fi movie. We waited for 6 min for the train which felt like 20min. I was just the beginning of the time dilation.

00.20 We were walking in the street. OEVs increased. Everything around us was moving and breathing. They were all holograms which were exactly like the movie holograms.
I cannot give the exact time info regarding the rest of the trip because sense of time was really fucked up.
My OEVs and CEVs were so intense that sometimes I couldn't even see in front of me. There was a storm of colors. People's faces were melting. I didn't know where I was from time to time although I've been there before. Total alienation. If you see Scanner's Darkly you would understand my field of vision. This was the first episode.

The second episode began with us going to an underground club. Lots of dubstep and mdma people. By the way my whole bodily sensations were gone at that time like I was just two experimenting eyes. I didn't feel the cold or anything around me. Anyways, we were in the club. Normally I really enjoy that music and I would dance. But I stood still in the club, didn't want to move at all, because I was processing the image in front of me. What I saw was deformed half orcs half humans dancing in a way that they are in some kind of ritual. Their eyes were white and just like some evil eyes. That part was just like the bar scene where Depp was freaked by the reptiles in Fear and Loathing in Las Vegas. As expected I went outside thinking of going to home. I spent some time outside of the club.

Third episode, we went home, turned on the tv. Wow, images were like in the house. Sometime later that thing changed. I was seeing it pixel by pixel which was strange because it was a huge fucking hd led. Audio is also distorted. Sometimes it was slow mo, sometimes although it was English, I was hearing German which I barely knew. Then I went to bathroom which was whole different reality. I couldn't go back to living room. I was so amazed by the patterns on the wall. Seeing lots of stuff, kind of living in it.

Fourth episode, went to bed (7 hours were passed). Total darkness. I was hallucinating madly. I didn't even know if my eyes are open or not. I was hearing voices, songs. Seeing multiple scenes, living in them but just for seconds. Then I fell asleep, I really don't know when.

Well 7 hours of intense OEVs and CEVs. I am really impressed. I really couldn't understand if that was a bad trip or not. Most of the time I was trying to comprehend what was just happening for it was changing rapidly. Honestly that feeling of not knowing where you are or with whom is so annoying. A weak person can easily lose his/her mind. But that was my first experience, I really didn't want to call it a bad trip. I would advise taking the half tab for the inexperienced users. By the way next day I was still feeling it in my mind. But in a clean way, I felt like I was enlightened somehow.

I could really get some advice from experienced users regarding the negative parts of my experience.
 
You took a large dose of an incredibly powerful psychedelic in a challenging setting, and it was your first time. Nothing you experienced seems out of the ordinary.

As for advice, next time take less and do so in a very comfortable setting. Some people never become comfortable with tripping around strangers, for most it takes several trips.
 
Yeah I'm just thinking the same thing. I'll try the half tab next time and a more comfortable setting. But I really want to know that feeling of alienation happened because of the dose or the setting. Guess I have to experience it further in order to understand it. Thanks for the reply.
 
I would say yes but experiences on this appear to be highly varried.

Checked on food high in Magnesium, a supplement would do the trick but I was just curious about my own diet and what was already built in that may have lessened what some have complained about


SO I eat a ton of foods high in Magnesium, I am not vegan or vegetarian, but I eat alot of brown rice and seeds and nuts all good sources of magnesium. like I said 500 ug gave me cold feet only mildly uncomfortable only noticed in the last half hour to 45 minutes of the ride.


Give what I read on Erowid about a bad time and doctors reporting magnesium and potassium levels were depleated I recomend consuming large amounts of bannanas rice, white beans, and good natural stuff the week before jumping into 25i
 
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