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The Big & Dandy 25I-NBOMe Thread (3rd edition)

What [b]in your experience[/b] would be a maximum responsible buccal dose for 25I?

  • up to 500 μg

    Votes: 9 8.1%
  • up to 750 μg

    Votes: 17 15.3%
  • up to 1000 μg

    Votes: 32 28.8%
  • up to 1500 μg

    Votes: 30 27.0%
  • up to 2000 μg

    Votes: 14 12.6%
  • a dose higher than 2000 μg

    Votes: 9 8.1%

  • Total voters
    111
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I would say it's inadvisable given that people have been randomly dying from insufflated doses and IM injection is far more potent than insufflation. I don't have a needle stigma (actually a type 1 diabetic who uses needles every day & has SC'd 2c-i a couple times) but I think that with the NBOMe's specifically increasing the potency of the ROA is not a good idea by any means. Especially with the extremely low dose and margin of safety, injecting is only going to increase the risk of overdosing. I would say try it with a different chemical. There is no reason why injecting should be substantially easier than making blotters, if you've done the volumetric measuring accurately (which you DAMN WELL BETTER if you're going to be injecting, let alone making blotters!!) then it's a comparatively easy step laying the solution on blotter.
 
Well lets say the solution was known to a pretty high degree of accuracy. i should have access to a 0.1mg analytical balance, whose error is +-0.2mg. it wouldn't be a good idea at the moment as i only have 10mg, but say i order another 50, a solution of 50mg +- 200ug in 100ml solution. Even if it is so much more potent that say, 100ug is a good dose i should be able to measure out 100ug in 0.2 ml with an error of 4/5 of ug all other measurements being perfect. but as they won't be 100% i'll call it an error 10-15ug. that should be a narrow enough margin of error shouldn't it?

my thinking was it'd allow for much more accurate dosing as i wouldn't have to worry about not getting full absorption and, I imagine, a faster come up.But I wont be doing anything unless i can find some info on what the equivalent IM doses would be relative to sublingual.
 
I remember Psydon00m, or what ever his name is, IM'ing 25C in the 25C thread. I'll see if I can find it.

Anyway, I'd say it's probably safer with 25C than with 25I, since 25I seems to be more "adrenergic" and has caused a few death's, which 25C hasn't, as far as I know.

I see your reason for wanting to IM, but honestly, sublingual really works fine if you do it right.

Edit: here it is, seems he IM'ed 25I too.

NSFW for lenght.

NSFW:

Well, at the last possible day she could arrive and still be “this week” my package was waiting in the mail this fine morning. As promised, I IMd ~50 ug, then ~50 ug more about a half hour later. I haven’t noticed any unexpected increase in potency or in the speed of onset relative to the other ROAs reported here, at least not to any degree more than would be expected using IM over insufflated or rectal with other substances.

It’s now 2 hours after that first dose and I just finished off a full mg IM. It’s impossible to say how much of that mg has been absorbed by developing tolerance during the interim hours but, oh well, there you have it.

In a few hours the university theater is screening Gaspar Noe's “Enter the Void,” so I wanted to prepare. Prior to this last injection, I felt less as though I would be entering a void and more that I would merely be a wallflower on the dance floor of oblivion. Now things are getting more interesting. It’s very lucid, the most lucid psychedelic I’ve ever used. Like water into water, any one of its psychic manifestations blends into the innumerable perturbations of the others. It’s just as I imagined a highly-selective 5-HT2a agonist would be.

It’s what in my more ignorant days I imagined “clean” LSD would feel like, before I got a look at the list of receptors she gets down with and found out what a skank Lucy really is.
So after class this morning I started IMing this again. It's been two days since I last, and first, used it and I was able to trip decently for a few hours off of 1 mg earlier this afternoon. The tolerance was clearly reduced but far from gone. It's been about five hours since then and I recently IMd ~2.5 - 3 mg more over the course of about 40 minutes out of curiosity. I just finished the second half of that injection. The tolerance effects are definitely strong! I'm tripping, that's for sure, but only at around a ++. It takes about 20 minutes to start to kick in using IM. I expect it to build a little more yet but to remain easily manageable. I'll update if anything unexpected happens. Until then I'm going to amuse myself with a psychedelic trip to the local freak-run video store. Love those guys!

EDIT: It's 3 hrs later and I've added DXM, ondansetron, and ketamine into the mix. The dissociatives definitely make the 25C's effects more prominent. This chemical is extremely malleable. As I type this and glance around the room things appear essentially as they normally do, yet just a few minutes ago while listening to music the walls were crawling with multicolored clockwork. It's responsive to conscious attention in a way that could give this chemical a lot of utility. It's almost like I could go through a normal day like this and experience no hindrances from the chemical, but when I focus its effects start blooming around me.

I'm curious to hear any comparisons with other selective 5HT2a agonists. What accounts for the differences in their qualitative effects neurobiologically?
^With most fast onset psychedelics (whether it be due to quick metabolism orally or because you IMd it or something) I've found doing the full dose at once results in an overall more profound experience, even if the onset can be hectic. However, because 25C tends to be such a lucid experience, I don't think it's a big a deal (with a strong ego dissolver or head fucker it's more important). Still, tolerance development is rapid with it in my experience, so I try to get it all dosed via either IM injection or liquid insufflation within an hour.

Last time I did 25C I had to do ~2.5 mg of it over an hour to get where I wanted, which is unusual (my usual dose is 1 mg via IM or liquid insufflation). I weighed out 4 mg on one scale, then dumped it on another scale that registered it as 5 mg, then re-weighed on both scales and got the same figures. I dissolved it in saline and used liquid measurement to liquid insufflate ~700 ug in 7 insulin units by spraying it into my nasal membranes. This resulted in a generic psychedelic body vibration only. I never swallowed any as far as I could tell. I had tried IM injecting 25I the week previous, twice, each time only getting a light experience (no visuals at all). Over the weekend I did 4-ho-DPT and DPT with aMT and tripped nicely, so the 25I did not establish a tolerance to psychedelics. I thought maybe I had bad 25I, but then it took so much to trip off of the 25C I've used successfully at 1 mg four times previously using the same measurement method and scales. I have no idea what's going on with the NBOMes and me.
 
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Doorkey, I know nothing about IMing the stuff but the nasal ROA with 25I in vodka is a fast, fast, hard come up. Visual effects within 5 minutes with strong body load during the come up and though it takes over an hour to hit full peak you're very nearly there within less than 30 minutes and that speed of onset is intense enough, trust me. As I say I dunno that IM would be any faster than that anyways but if so I highly doubt that would be especially desirable.
 
IM meaning intra what now??? oh Intramuscular nah not for me


ANyway got my free sample today.. pretty much what I expected 10mg doesn't look like much. ittle little bit of fine white powder, some CLEARLy stuck to the side of the bag.

I have no intention of being an idiot and trying to eyeball this.. I will verify the 10mg count by solving it with 10ml of Belvy vodka.... let that evaporate then weigh it on my scale... Its a realy nice lab certified Ohaus... so no fears.

Question if just planning to verify would IPA be a better idea?? I mean would it just evap a bit more quickly...


Then I plan to split it into roungly 5 and 5

then I plan to prep the 5 for my wife and I. Starting out small... 1 mg for me 700 micro for her with the idea that we may or may not redose


I will let you know what the results are... this will not happen for a bit though

Holidays


Cheers
 
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i suppose if pysdon00m hasnt noticed any increase in potency through IM dosing than there doesnt seem to be much advantage to IMing over liquid insufflation, although you can't really say that for definite based on just his experiences. in any case, it's not like 25i is that expensive and i have to make every mg count. I hadnt heard of liquid insufflation as an ROA before but it seems promising. visual effects in 5 minutes? sounds like fun! would you say that the body load is a lot stronger than an equal dose sublingually?
 
^Yes, but insufflated dosing also carries with it a greater risk of overdose/dying than sublingual/buccal. If this is your first time with 25i, what's the rush?
 
Last night I had my third 25i trip. My first trip consisted of a 1mg tab at the start, with a redose of 1mg at around t+6H. Being that this was my third trip ever, I never fully completed my trip report because I kind of lost myself in the beauty. I really noticed the potential this drug has for music on this trip. Here's an incomplete trip report from the first 25i trip:



So, my second trip on 25i was spent mostly listening to music again because I love what this drug does for spacial positioning on well produced albums. There's not much to tell here, but the dose was a more modest 750ug.

Gender: Male
Weight: 125 lbs
Age: 19

So last night, I started with 750ug again, but 40 minutes later decided to take the other 250ug for a 1mg dose. I started by watching Colors_LIVE, a live album by Between the Buried and Me that's about 2 hours long. As the first set played, I noticed the usual creeping effects. Colors were enhanced, sound felt as if it surrounded me, light tracers and trails were forming slowly and strongly.

About 50 minutes in I was coming up pretty well, at about a ++ at this point. After 30 more minutes or so I decide to pause the concert and just watch some TV. The come up is getting incredibly overwhelming at this point, so I turn on something familiar, Friends. It's the thanksgiving episode, and I'm laughing hysterically at everything that happens. +++ and it is at this point that the trip becomes a little dissociative, and time dilation is doing crazy things to me. I look at the clock when I feel a considerable amount of time has passed, but usually it's never more than 7 or 8 minutes. When Friends ends I try to find something else.

Ah! Dumb and Dumber! I haven't seen this movie in 4 years or so and began watching right when they swap vehicles. This movie is a MASTERPIECE while tripping your balls off. Everything that happens is hilarious and familiar but induces a lot of thought as to what is all going on in this movie. Here is where I'm getting some VERY dissociative effects, kind of leaving my body and just becoming a point in space. A full ++++ is taking place and a couple of people come downstairs. Communication is utterly impossible as I'm peaking and I can barely keep a linear train of thought with the movie playing in the background. They leave me to myself seeing as I'm in my own world and I begin listening to an album in 5.1.

WHOA this is most of the reason I wanted to trip in the first place. Listening to this album sober puts me into a trance with the clever mixing and I wanted to see how spacial awareness was on 25i. It is incredible. I'm casually talking with a few friends on the computer as the music sucks me in. The trip mellows into a steady +++/++++ at this point and most of the vasoconstriction is gone and I'm feeling very euphoric. At the end of this album I decide to continue talking to friends and just hang out for 30 minutes or so. I then get up to move around, and decide to clean up the basement a little.

After cleaning up, I decide to listen to BTBAM's most recent album, Parallax II: Future Sequence. Pure magic. The fractalling visuals and breathing objects all around me swirl and undulate with the music as I just lay back with my mouth wide open. Closing my eyes really dissociates myself into the music, as I feel one with it. I can't even come close to dissociating like this on two hits of acid, but that's an entirely different experience.

I switch to listening to The Sauce by Pantyraid. Seriously some of the best music I have listened to while tripping. When things get very glitchy, my visuals get ultra intense and pull me back into a ++++ at times. I smoke a few bowls as I lay down to get to sleep easier, and listen to some Motion City Soundtrack as I wind down. At this point it's about 8 hours since I dropped and the visuals are very light, still a gentle mind fuck, but getting to sleep wasn't too bad at all.

Overall this trip was extremely eye opening for myself. This stuff is a serious psychedelic, and I don't think a mixture would be a wise choice with this one. The full agonization of the 5HT2-A receptor is a big reason for this.

It's worth noting I am lucky I didn't lose my mind on my first trip, and I URGE anybody trying this drug to start low, like in the 300ug range. There really is a lot of unpredictability in this drug, and the dissociation at the peak can be frightening if you're not ready for the feeling.


On a side note, cryptix420 should really slow his roll.

the fuck?

i think you're just jealous my serotonin is stronger than yours
 
How many people have tried combinations with this drug?

Excluding marijuana, my only combination was dosing 2mg in blotter form, then about 3 hours later snorted 4mg (along with some redoses later on) of hydromorphone. After 5 minutes visuals started seeping back into my vision, and I was overtaken by the best euphoria I have ever felt. It also really helped with the after-trip restlessness and general leftover mental stimulation. This is one of my favorite drug combinations, though lsd works well as a replacement for 25i.
 
I have combined 25X's with mushrooms, lsd, pot, poppers and MDMA.

3g's of cubensis and 1800ug of 25X was my first "bad"trip. Very agonizing but I do not regret experiencing it.
1300ug of 25X and 100mg of MDMA was fantastic. Most likely the strongest visuals I have ever seen.
Poppers will make your head explode.
Pot amplifies the trip tenfold.
 
I agree that handling nbome powder requires SERIOUS attention to detail and safety.

Ive dosed myself via this method before and it resulted in me suffering mild body-load, insomnia, and basic psychelia through most of the day, but was not much beyond threshold. You need a dust mask and gloves at bare minimum, otherwise the powder can eaily be absorbed via your lungs or hands, resulting in pronounced effects. That said, it is not difficult to handle if you have worked with psychedelic powders before (for example, 2C-I).

Doing the math is the more important factor, making sure ratios are double-checked and if converting or complexing, molar ratios are precise.
 
could someone elaborate on this?

Yes, what Gusie is saying here (on page 4) is that at festivals this drug or other NBOMe compounds may be offered on blotter. However they do not work if you swallow them immediately, since NBOMe's are not active orally. So if you are at a festival and someone tells you they have acid but you need to keep it between your gums for it to work... it is not acid but instead an NBOMe or related compound. Placed between the gums it is absorbed bucally / sublingually (in the mouth) directly into the bloodstream.

(Note that NBOMe's could also be offered as liquid at festivals, it is certainly possible. Not only is it known to happen, people died from dropping 'foreign' 25I at a festival i.e. Voodoo Fest)

Always be wary buying drugs at raves, parties or festivals from strangers. There are weird people out there and a lot of careless, reckless and ignorant ones. Who knows what you get?
With LSD, a high dose can be intense but you will survive. Certain other drugs may not be as forgiving.
 
I've got my hands on some blotters that have been tested to be 600ug of 251-NBOMe. I've taken LSD a few times before but usually I take a small amount of Valium prior so I don't get anxiety. I start work in 4 hours so I was wondering if it would be safe to dose or would it just fuck me up. My job is easy but it's long and boring, I only need to sit at a cubicle and be able to read a script. Would this drug be safe in the workplace or a good way to get me fired?
 
Reactions to this are varied, some are pretty tolerant and stay lucid on it even at quite high doses while others go delirious or strong +++ or even die at doses at which the tolerant ones had no physical problems at.

I think that while generally in a safe / controlled environment you should be okay trying that because there can be people to calm you down and you have no responsibilities, doing it in an uncontrolled setting like a workplace where "anomalous behavior" could raise a shitstorm can have consequences such as getting fired, arrested or differently. The probabalistics of that might not be super serious but I guess the question is if 'long and boring' work is a reason to take a mild chance of shitty disaster... or if it more typically is a reason to reconsider your career path instead?

Oh, I didn't post that question too suggestively did I? :)
 
I dosed 300ug over an hour ago, can't really feel anything yet. Work is still a few hours away if I started tripping out of control I have plenty of benzos to help. I'm a full-time student so although it's a boring job it's good hours and good pay and the boss is chill as fuck, it's boring but it's a lot better then being unemployed.
 
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