6apb vs mdma and methylone

[losfalcor]

How close does a 6apb trip compare to MDMA and methylone. Ive tried methylone which seemed to be a closer chemical structure to MDMA than 6apb anf 5apb. But i hear that 6apb had the euphoria with the speedy feeling of methylone. I was woundering if i would get a more MDMA like feeling if i mixed the two (6apb and methylone). Its been awhile since ive had pure MDMA, but from what i can tell, the roll is more solid and longer with MDMA than methylone. But i was really considering trying 6apb really soon. It sounds like an awesome experince. So what you guys think? MDMA and methylone vs 6pb.. What is most like MDMA

 

[Dmytry]

methylone takes about 15-25 minutes to peak and the peak lasts about an hour, 6-apb takes about 60-90 minutes to peak and the roll lasts about 6 hours. so pretty much youd be coming off the methylone while the 6-apb was peaking.
you would not get a more mdma-like feeling if you mixed them, the methylone mostly releases norepinepherine, about 1/3 the serotonin of mdma, and little dopamine. mdma is very serotonin heavy. 6-apb is the most balanced of the 3. also, none of them have the magic/empathy of mdma.
if you really want to mix something with 6-apb, why not try 5-apb. its supposed to make the roll a lot more like mda than 6-apb alone.

 

[Folley]

the methylone mostly releases norepinepherine, about 1/3 the serotonin of mdma, and little dopamine.

Huh.. I'd be very surprised if NE was the main action methylone took. Do you have any source for that? I'm not calling you out or anything, I'm genuinely interested

and do remember that empathogenic drugs don't just work on those three neurochemicals, Oxytocin (the love hormone) and Prolactin (orgasm hormone) are also released in large amounts when you roll.



Methylone was meh to me, seemed like an MDMA imposter. I'd like to try 6-APB, I hear it's more like MDA than MDMA though. In the end, if you want MDMA.. you have to take MDMA. No other chemical will come close, IME.

 

[Dmytry]

the beta-ketone on an amphetamine backbone severly limits any dopamine release, but if anything it may still allow dopamine reuptake inhibition (like mdpv). the beta-ketone allows for significant affinity at norephinepherine receptors (like psudoephedrine. not a beta-ketone but has hydrogen bonding capabilities and electron density at the same exact region)
also, oxytocin release is primarily understood to be caused by activation of the 5-ht1a receptor. because of the beta-ketone, methylone cannot bind as effectively as mdma at any of the serotonin receptors.
im still looking for the paper i read with exact values for each of the receptors, but until i find it, it should be obvious that methylone releases much less serotonin than mdma due to the fact you can keep redosing throughout a night and with relatively zero hangover or mid-week depression

 

[losfalcor]

I did notice that methylone kicks in pretty fast and is short lived, however will have you wired and wanting to redose to keep the effects going. Sounds like 6apb is a steadier, longer lasting and possibly harder roll without the stimulating effects of methylone. Im almost certain i wanna try it now. Sounds like the better of the two

 

[Crashing]

IV Methylone feels just like a 1 hour instant peak-roll and I used to redose over and over with really no negative effects or comedown.

 

[losfalcor]

So now I'm thinking about mixing 6apb with 5apb at about a 2:3 ratio, wait about 30 -35minutes and take some menthylone. Sounds like alot of fun. I'm placing my order as soon as my new debit card is in. Ill hit you guys back with a report when I try it

 

[Albion]

I'd make that ratio 3:2 6-apb:5-apb since 5-apb is roughly a third more potent than 6-apb. And half the dose of each.

 

[losfalcor]

I'd make that ratio 3:2 6-apb:5-apb since 5-apb is roughly a third more potent than 6-apb. And half the dose of each.

Ya thats what i meant. Got my statistics backwards but knew what i was aiming for