Several days break between St Johns Wort and low-dose MDMA?

[rhml]

So, my fish started taking saint johns wort about 2 weeks ago, 700-1400mg a day, and my fish was planning on trying MDMA tonight for the first time. He did his research, and has found tons of info about the potential for serotonin syndrome arising from direct combination of these two, so therefore he stopped taking the St Johns wort 3 days ago. When he looked online, the only people who had a similar situation where they stopped taking SJW ahead of time were using the SJW for much longer periods than my fish (months as opposed to 1.5 weeks) and people suggested to stop anywhere from 4 days to 2 weeks before taking MDMA.

In any case, my fish is REALLY bummed about just finding this out a few days ago, and was really set on trying MDMA tonight at a rave. If he was only taking the 1400mg dose of SJW for a week and a half, is a 3-4 day period between quitting SJW and taking MDMA long enough, or does he still have a high risk of serotonin syndrome?

 

[JJ-180]

No. It's never "safe" to do drugs, but you should be all right.

 

[Mr.MDxx]

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[Folley]

Tell your fish to stop swimming... this is a harm reduction site, not the deep dark ocean


As you already know, SJW and MDMA are dangerous in combination... how many days does is take for SJW to be out of your system though? Well, it's half life (time it takes for half of it to leave the body) is 24-48 hours... so by three days, you're still likely to have more than 1/4th of the dose still in your system.

So, no. I say it's not safe. Wait a week at least, it's not worth the risk of seizures.. or worse...

 

[rhml]

Just for future reference no form of "SWIM" is allowed here, it offers you NO legal protection and everyone on here knows it's you. It also makes it very difficult to read!



Read the forum guidelines before posting.

http://www.bluelight.ru/vb/threads/124579-Ecstasy-Discussion-Posting-Guidelines?s=

Sorry about that.. I usually read forum rules when I join, just wanted to ask this question as soon as possible. Thanks for the heads up.

Tell your fish to stop swimming... this is a harm reduction site, not the deep dark ocean


As you already know, SJW and MDMA are dangerous in combination... how many days does is take for SJW to be out of your system though? Well, it's half life (time it takes for half of it to leave the body) is 24-48 hours... so by three days, you're still likely to have more than 1/4th of the dose still in your system.

So, no. I say it's not safe. Wait a week at least, it's not worth the risk of seizures.. or worse...

That's what I was expecting.. Man this event would be the perfect first MDMA experience, Unfortunate So you still think the risk is huge even if the SJW supplementation was only for a week? People seem to often bring up how SJW "takes time to build up in your system", if it even works at all.. Still think the MAOI effects are going to be dangerous enough after only a week of use?

I'm mostly asking out of curiosity, i'm pretty much set on postponing until a later date

 

[somedude1942]

from personal experience, i believe that you will be fine. i don't remember exactly how many days i waited after SJW to roll but it was pretty close to three or four days. to actually experience serotonin syndrome, i think you would need to have taken a relatively high dosage of both back to back. then again, if you really are hesitant then take what i suggest with a grain of salt.

 

[rhml]

from personal experience, i believe that you will be fine. i don't remember exactly how many days i waited after SJW to roll but it was pretty close to three or four days. to actually experience serotonin syndrome, i think you would need to have taken a relatively high dosage of both back to back. then again, if you really are hesitant then take what i suggest with a grain of salt.

Were you taking the SJW for an extended period of time?

 

[somedude1942]

900 mg a day for about 3 months. but like i said, i don't want to convince you to do something you aren't comfortable with. i'm not sure how SJW actually changes your brain chemistry after prolonged usage. i noticed it was gradually becoming less effective over time so i may have developed a tolerance to it, so to speak.

on a related note, after a few months usage you may find SJW ineffective and i highly suggest taking a break from it on a regular basis

 

[Folley]

If you'll do a search I believe there is a thread where someone took a regular dose of the two and went through something that was, or at least very similar to, Serotonin Syndrome.

The risk isn't definite, but it's still there.. personally, I'd probably wait a while just to make sure I had the best roll as possible.

 

[rhml]

900 mg a day for about 3 months. but like i said, i don't want to convince you to do something you aren't comfortable with. i'm not sure how SJW actually changes your brain chemistry after prolonged usage. i noticed it was gradually becoming less effective over time so i may have developed a tolerance to it, so to speak.

on a related note, after a few months usage you may find SJW ineffective and i highly suggest taking a break from it on a regular basis

I honestly don't really have any use for the stuff, i probably wont take it again, especially after all the various infor about it that I've found while researching this specific serotonin-syndrome question. I mistakenly was taking it for a week with some Antioxidants and Piracetam as a preload, because I thought I had read that SJW was recommended as a preload supplement as well, but I was obviously mistaking it for something else and I am reallly regretting the fact that I didnt double check before I took it.

If you'll do a search I believe there is a thread where someone took a regular dose of the two and went through something that was, or at least very similar to, Serotonin Syndrome.

The risk isn't definite, but it's still there.. personally, I'd probably wait a while just to make sure I had the best roll as possible.

I think I read that thread some time in the last day or two while looking for info on this.
That's actually my primary reason I want to wait. I think taking 25-50mg would most likely be fine, but i've always found this chemical fascinating and would love to wait to really do it. Just won't have an opportunity like this event maybe ever again, so i'm particularly bummed. But, life isn't always fair I suppose