Question about using baking soda to potentiate amphetamines...

[Foreigner]

I find grapefruit juice potentiates LSD and MDMA if I take it a few hours before, freshly squeezed. I know some people will disagree with me but I swear by it.

I didn't know that lowering stomach acidity makes amphetamines absorb better. Would that include MDMA?

 

[Swimmingdancer]

I have been told that orange juice will potentiate meth.

I have been told that milk will reduce the effects.

I have been told nothing of baking soda. Or tums.

I must be talking to idiots?

I find grapefruit juice potentiates LSD and MDMA if I take it a few hours before, freshly squeezed. I know some people will disagree with me but I swear by it.

I didn't know that lowering stomach acidity makes amphetamines absorb better. Would that include MDMA?

I've heard that lowering stomach acidity helps MDMA absorb, I have never deliberately tried it, but one would think it would work on MDMA, it is an amphetamine.

Grapefruit juice, and orange juice (to a lower degree), contain naringin, which inhibits the liver enzyme CYP3A4, which metabolizes MDMA (and many other drugs). So just because a fruit/juice is acidic does not necessarily mean it will decrease the affects of all amphetamines. People have said that they felt that these juices slowed the onset of MDMA but heightened and/or extended the effects, which makes sense. MDMA itself inhibits this enzyme, so it is believed that redosing results in higher concentrations of MDMA which last for longer amounts of time. BUT, as far as I know, methamphetamine is not metabolized by CYP3A4 and is primarily metabolized by CYP2D6, which means that grapefruit/orange juice should not potentiate meth. (But who knows for certain, we don't fully understand the enzyme inhibition by naringin yet).

As for to the idea that milk could decrease the effects of meth, I have never heard of that and it makes no sense to me.

 

[Tarnum]

Stay away from using baking soda or tums to potentiate amphetamines. Using potentiators in general is simply a bad idea, since your brain will adjust to the higher concentration of the drug in your bloodstream for a longer period of time, raising your tolerance to adjust to it, which means you will be forced to take your potentiators every single time you take a dose.

Ampetamines are already powerful and destructive enough, do you really need to potentiate them and risk even more neurotoxicity?

Isnt that just like saying dont take more of your drug because your brain will adjust to the higher concentration? Thats what potentiators are used for lol to increase the concentration of the drug.

 

[Swimmingdancer]

^Yeah, I don't see anything wrong with educated use of potentiators if the alternative is to just take a higher quantity of the drug. Even in a medical setting potentiators are sometimes used in order for the patient to be able to take a lower dose of the drug than they would have to otherwise.

 

[JackiesBabyy]

Isnt that just like saying dont take more of your drug because your brain will adjust to the higher concentration? Thats what potentiators are used for lol to increase the concentration of the drug.

This is correct, reading Ergic's post made me feel like I left bluelight and entered PSA-land where people say common-sense things worded in ways that make it sound scary.

 

[Swimmingdancer]

Maybe Ergic was just worried because a lot of people don't actually realize that using a potentiator is pretty much equivalent to taking a higher dose of the drug.

 

[JackiesBabyy]

Maybe Ergic was just worried because a lot of people don't actually realize that using a potentiator is pretty much equivalent to taking a higher dose of the drug.

I suppose people may not realize that, but he could have just SAID that like you did instead of wording it like a scare-mongering PSA

 

[kingtweaker92]

ah, i see. so, in conclusion it can make the experience more enjoyed when eaten

but at the same time render it un-detectable in urine.
gotcha!

 

[Renz Envy]

I suppose people may not realize that, but he could have just SAID that like you did instead of wording it like a scare-mongering PSA

PSA: Baking soda and crystal meth was a good idea. They said. Now I'm blind and deaf. People call me Helen Keller on Speed. Meth: Not going to teach helpful tips if you decide to do it.

HR:

Stay away from using baking soda or tums to potentiate amphetamines. Using potentiators in general is simply a bad idea, since your brain will adjust to the higher concentration of the drug in your bloodstream for a longer period of time, raising your tolerance to adjust to it, which means you will be forced to take your potentiators every single time you take a dose.

Ampetamines are already powerful and destructive enough, do you really need to potentiate them and risk even more neurotoxicity?

IMO a good HR post will essentially be a tutorial and/or a disclaimer. I don't see anything untrue in that post.

 

[beagleboy]

This link shows how to prevente dexadrine/adderall/(speed) and methamphetamine tolerance.
The logic is that you build a tolerance and dont feel the effects of the drug when you use it for a period of time. In order to feel that "High" you got when you took it for the first couple of times or binged, ( it only takes a couple binges to build tolerance) you need to supplement yourself. This is Harm reduction.

http://www.bluelight.ru/vb/threads/97021-Speed-Meth-tolerance-prevention-reduction-long?
highlight=bioavailability+amphetamine