Codeine & CWE Megathread: Version II - [insert witty title]

[Stato]

Went out of my way to purchase a couple of buchner funnels, and a vacuum pump and flask. The Buchner funnels being reusable glassware with 15-20micron filters, and being able to add vacuum to speed up a cwe is fucking awesome. 5 minute job!

I'll clean my glassware and show you guys a CWE tomorrow if I can.

For those who can purchase glassware such as a buchner funnel, a vacuum source, and the appropriate flask and mating, they sure seem to get the job done quickly and I would daresay a sintered glass filter (15-20 micron) would be a touch better than coffee filters.

Of course, this means an $$, coffee filters are cheap and do the job, have done for me for a long time!

 

[Ashley]

Went out of my way to purchase a couple of buchner funnels, and a vacuum pump and flask. The Buchner funnels being reusable glassware with 15-20micron filters, and being able to add vacuum to speed up a cwe is fucking awesome. 5 minute job!

I'll clean my glassware and show you guys a CWE tomorrow if I can.

For those who can purchase glassware such as a buchner funnel, a vacuum source, and the appropriate flask and mating, they sure seem to get the job done quickly and I would daresay a sintered glass filter (15-20 micron) would be a touch better than coffee filters.

Of course, this means an $$, coffee filters are cheap and do the job, have done for me for a long time!

Awesome! I'm spewing I don't have any glassware or other bits and bobs at the moment, otherwise I would do exactly as you.

Ash.

 

[Stato]

I bought it online (local supplier though, after a cautious email re legalities), I was considering a full kit as I was even leaning towards a TAFE course to get myself on the path of a chemist, not because I'd ever want that qualification, I just like the knowledge.

Like I said, I may perform a CWE tomorrow, probably on 40x 10mg codeine 500mg apap tablets as they're <NO PRICES!!>. Depends.

I'd like to further evaporate the liquid (given I can now use very very little amounts of water as I'm aided by a vacuum instead of relying on gravity and broken filters) -- but I'm too lazy and not quite sure How I'd accomplish it.

I'd like a decent set of scales so If I did evaporate the mix I'd be able to weigh the resulting powder and work out an approximate yield (of course there is/may be water soluable binders, fillers, shining agents, etc... ) It'd be good to be able to work out a dose and cap up 50mg or 100mg codeine capsules, I suppose you could estimate 90+% yield, and there being 400mg per pack.... 4 capsules of whatever powder is left after evaporation would do it. Still dodgy.

I just hear too many stories (and have seen first hand) panadeine forte prescribed after discharge from hospital, where 5mg oxy/endones were given every 4 hours...... (This is public hospitals doing it here) Private specialists seem to be OK. I was sent home with a box of endone and managed a repeat from my GP for a tonsillectomy. Only time I've had fortes prescribed was for extraction of 4 wisdom teeth, full anesthesia.

I guess what I'm saying is I believe in proper pain relief, and It's a shame (IMHO) that the public hospitals post op seem to be lacking in this department.

 

[Ashley]

I bought it online (local supplier though, after a cautious email re legalities), I was considering a full kit as I was even leaning towards a TAFE course to get myself on the path of a chemist, not because I'd ever want that qualification, I just like the knowledge.

Like I said, I may perform a CWE tomorrow, probably on 40x 10mg codeine 500mg apap tablets as they're <NO PRICES!!> Depends.

I'd like to further evaporate the liquid (given I can now use very very little amounts of water as I'm aided by a vacuum instead of relying on gravity and broken filters) -- but I'm too lazy and not quite sure How I'd accomplish it.

I'd like a decent set of scales so If I did evaporate the mix I'd be able to weigh the resulting powder and work out an approximate yield (of course there is/may be water soluable binders, fillers, shining agents, etc... ) It'd be good to be able to work out a dose and cap up 50mg or 100mg codeine capsules, I suppose you could estimate 90+% yield, and there being 400mg per pack.... 4 capsules of whatever powder is left after evaporation would do it. Still dodgy.

Vacuum evaporation would be ideal, obviously, seeing as you've got vacuum now. You could do a wash on it with a solvent and recrystallize it if you can be bothered. I'm planning on doing just that as soon as I acquire new glassware, condensor, etc. Cleaning it up to codeine phosphate as a powder, for uses in other matters. I just bought a nice set of 0.00g scales the other week, cool leather pouch and a green LED screen.

A.

 

[Stato]

(EDIT: Oh, yes, Vacuum Evaporation indeed would be ideal. I'm just not sure how I'd get the solid out of the beaker as a solid Perhaps with an alcohol that evaporates quite quickly under normal conditions? Non-methylated Methylated spirits (95% ethanol) should do it?!). -- (You have me wanting to do the 600mg mydol now! haha)

(PS: sorry footscrazy for the prices, !! Sometimes these things slip my mind, I know the rules... no excuses, sorry mate to cause you work there)

Ended up doing my CWE with the buchner funnel and vacuum, first CWE was a little slow (20 minutes!) because I hadn't properly de-clogged the funnel since last time.... Gave it a good wash, with both metho (ethanol) and water.

Second CWE, absolutely flawless, the paracetamol is literally almost hard to the touch after only a minute or two of vacuum through the filter. I of course usually add an extra ml or two of water at this stage and let it go through the filter again (re-wetting some of the para)

Since I bought 3 boxes of codeine (2 generic 40x 10mg codeine, and 1 box of mydol 15 x40), I've only done the 2 generic and not the mydol (yeah, single dose 800mg less cwe losses...) I'll make sure I video the next CWE tomorrow, I'll do this CWE with the intention of evaporating the liquid, since I seem to use far less liquid with this new method and not using coffee filters.

Just a note as to the current chems in my system:

800mg codeine input (assume 95%+ yield) so, perhaps 770mg or more in my system.
75mcg clonidine (catapres)
25mg Doxylamine (Generic Sleep-Aid, lol)
12mg Cyproheptadine (Periactin) - Antihistamine, I bought it because it's... well... Let's just say my girlfriend is on SSRI's (Read the wikipedia if you want to figure this out)
25mg Promethazine (Phenergan)

It's been a while (5 weeks+) since I last had any codeine. Tramadol (even at 700mg) doesn't seem to produce the histamine release codeine does?!


EDIT: (1.5 hours in since injestion, mad histamine release. Heavy nice codeine feeling. 800mg filtered this way definitely has more of a yield, I would estimate I was losing 20% just being sloppy with coffee filters! Since I was always impatient)

another edit.... Decided to go ahead with the experiment and CWE the 600mg (40x 15) mydol. Will get this on video to show a vacuum CWE.

 

[Stato]

I'm not going to edit the above post again and again, with every thought that comes to mind! It'd be a wall of text....

So, as we all know, some paracetamol will end up in the final product, which will be evident when I evaporate it....

Just thinking, I could then CWE it again, and again, eventually ending up with pretty much straight codeine I would hope, traces of paracetamol only)

I haven't got the chart of solubilities in front of me, so someone please correct me if I'm wrong?

 

[Sustanon]

Just did another experiment using my method which is run the extraction through a tight woven shirt then filtering with a coffee filter and this is the end result. (Ibu / codeine pills)

These are the coffee filters that was used for the single extraction, used more to speed up the process otherwise ud be waiting day and night for it to filter completely. Barely anything remained in the coffee filters as you can see.

 

[88brenno]

Stato:Its good that your trying to get as clean product as you can, but don't let it give you a false sense of security, I don't know how well they work in terms of removing the suspended material. You should take milk thistle, again its not an assurance but its another measure you can take with excellent results. Also by repeating the CWE on your already filtered product will just absorb more of the solution.

Ash, good to hear you know regular use of any NSAID is a bad thing, you were just talking it up as if there were no danger, something along the lines of "everyone takes them every day without problems" so you can see where I am coming from. I would like to know how long it takes you to perform a CWE on ibu pills, as IME they just clog the filter and if you squeeze it you are letting not only the soluble ibu, but also suspended particles, which will increase the total amount of ibu in the CWE

 

[Stato]

88, I'm talking about evaporating it, down to powder, leaving a little paracetamol + all of the codeine originally CWE'd. and then RE-CWEing it, then re-evaporating, etc.

 

[Ashley]

I'm not going to edit the above post again and again, with every thought that comes to mind! It'd be a wall of text....

So, as we all know, some paracetamol will end up in the final product, which will be evident when I evaporate it....

Just thinking, I could then CWE it again, and again, eventually ending up with pretty much straight codeine I would hope, traces of paracetamol only)

I haven't got the chart of solubilities in front of me, so someone please correct me if I'm wrong?

Paracetamol is soluble in acetone, alcohol and other organic solvents. Codeine however is not soluble in acetone. So you could use anhydrous acetone to clean up the paracetamol remnants after performing the initial vacuum filtration. I bet you're stoked you can work under vacuum now, makes life so much easier.

A.

 

[Captain Brewster]

^^^^^^^ Stato whats wrong with periactin? I use it a lot to potentiate my codeine.

Fairly sedative and really cheap, comes in 100 pack that lasts for ages.

On another note, I went to my doc, I suffer from head pressures daily.
I've been prescribed imigran and maxalt, both didn't work. My doctor said I would have to take painkillers for it, so I got presrcibed fortes (30/500).
Now I went back for other issues and got a nice indian lady, (I was actually having trouble understanding a lot of what she said). I asked her if fortes can be presribed on repeat, she promptly said "no, you don't need a repeat".
I explained that I get them all the time and have been for years. She sort of shrugged me off. So I left it at that.
But at the end if the visit she asked me if I need more fortes, of course I said yes.

What I want to know is has anyone been on some sort of permanent script for them, or do you really have to keep seeing a doc to get them say, monthly?

 

[88brenno]

Okay never tried that, sounds too time-consuming, Id be all omnomnom as soon as I had the liquid. Looking forward to getting on tonight :D with as much potentiation as possible, only have 600mg Might do a Ibu CWE aswell lol

 

[Stato]

^^^^^^^ Stato whats wrong with periactin? I use it a lot to potentiate my codeine.

Fairly sedative and really cheap, comes in 100 pack that lasts for ages.

On another note, I went to my doc, I suffer from head pressures daily.
I've been prescribed imigran and maxalt, both didn't work. My doctor said I would have to take painkillers for it, so I got presrcibed fortes (30/500).
Now I went back for other issues and got a nice indian lady, (I was actually having trouble understanding a lot of what she said). I asked her if fortes can be presribed on repeat, she promptly said "no, you don't need a repeat".
I explained that I get them all the time and have been for years. She sort of shrugged me off. So I left it at that.
But at the end if the visit she asked me if I need more fortes, of course I said yes.

What I want to know is has anyone been on some sort of permanent script for them, or do you really have to keep seeing a doc to get them say, monthly?

Nothing is wrong with Periactin, we bought it because it's used off label to relieve SSRI induced sexual dysfunction . Normally i use phenergan to relieve+potentiate the nod. ... but since I haven't needed it to sleep (seroquel ftw), I haven't got any!. All I was saying is this is the first time I've used Periactin as an antihistamine.

 

[Captain Brewster]

^ wow, I used to take it daily for sleep a few years back, had no idea it helped with ssri sexual disfuntion

Used to knock me the fuck out back in the day.

 

[Dr Phibes]

Ibu is just too heavy to work with and clogs up filters and always comes out milky, though its cheaper. I don't do all the squeezing thing etc. unless i didn't plan ahead. I just put the para mixture in the fridge in a double coffee filter (turning one inside out so they fit together snug) and let it drip through overnight or overday, I throw away the still moist gunk in the filter and have pure clear water. Squeezing every last drop through and ending up with who-knows-how-much para in your mix is not worth it when you could have just put in an extra tab or two.

With solubility, I doubt you could come close to dissolving the theoretical maximum of either para or ibu, that would be like trying to dissolve a cup of sugar in a cup of water at room temperature. Codeine on the other hand will dissolve pretty instant since the theoretical max is something like 4 grams in 2.5 ml of water.

As for those questions on Milk Thistle, Thompsons is the only brand I can find that is 35g equiv. a pill. I take one or two a day. Chemist Wharehouse is the only place I can find them, if I can say that about vitamins, else look up Thompsons website. Studies and anecdotes about it are encouraging and it has been used for centuries as a liver tonic.

 

[Stato]

Yeah I think I'm with you on that Dr Phibes, even through a 15micron buchner funnel it comes through milky. No matter the brand, generic or some of the more known + brands.

I'll probably stick with non ibu, 40x 10mg cod boxes.

(just put 120 tablets through the funnel, almost crystal clear) 200ml of water at the end of it.

 

[88brenno]

Okay will keep an eye out for that one, what is the reccommended dosage, because I have seen Swisse 5gm daily, Natures Own 21gm daily, and now Thompsons (at least) 35gm daily, goes to show ya really need to look around.

I had a LFT, will keep yous posted too

 

[Sonny Jim]

Milk thistle (Silybum marianum)

Daily maintenance dose:
you want about 180mg of silymarin (actual silymarin content) twice daily. That's 180mg of silymarin (might be written as silybin or flavanolignans) . The amount of silymarin is alawys going to be less the the actual total dried weight of the Milk thistle herb in the tab/capsule. For example the Thompson's one's have 420mg of silymarin (written as 420mg silybin from memory) but have a total amount of dried Milk thistle herb as being something like 3500mg. By the way, Thompsons are one of the best OTC for quality and value IMHO but break them in half and space out the dosing by 45minutes if they bug your stomach, not that I am expecting they'd cause you trouble. They are supposed to be a 2 in 1 dose but I'm not sure if they are time release. This would make things more complicated so maybe crush them if they're the hard tabs.

I like to take it with a bit of food and one other thing I'll add is that very high doses can make soe people feel a bit light headed and maybe be a bit rough in the guts. This should be non existent at the recommended dose. If you want to take more than the recommended dose I recommend splitting it into two doses by about 2 hours.

Milk thistle as a powerful prophylactic :D

The main idea with dosing Milk Thistle is to have your liver saturated with silymarin before you ingest your liver toxins, which is as simple as taking the tablets an hour or so. I usually take at least 200mg silymarin an hour before but a little more, like a whole crushed Thompsons might be better if it's tolerated. I

not directed at you breno or anyone in particulars. I want to say that this stuff really does work (provided you get quality silymarin and most Aussie stuff seems good mate!) but I am not suggesting it can be used to take more liver toxin than you might usually. Just add it to your regular drug taking and you should experience some benefits. In the long term this is a very powerful herb capable of restoring the liver function tests of many booze fucked livers...maybe tell your parents about it a mildly fucked liver can cause all kinds of mildly fucked health concerns, maybe difficult to lose weight IMHO.

 

[Stato]

Ended up in emergency over the weekend, receiving doses totalling 0.2mg FENTANYL. Did not feel any pain relief at all.

Got sent home with 20 paandeine fortes.......

Ended up doing a filtration on 40 x 15, and 2x 40 x10 boxes of codeine. 1400mg, maybe 1300+ if a bit slack.Which I was, because I spilt my last lot of the fortes because it hurts so much.

 

[spacejunk]

^ hope you're ok dude. nothing too serious i hope?