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4-HO-MIPT & Methylone combination

tiger108

Greenlighter
Joined
Oct 10, 2009
Messages
15
Location
Los Angeles
Question about combining 4-HO-MIPT & Methyone, how do they synergize together or what is the best way to take them on the same day? I had great experiences with both chemicals on their own
I have 20mg of miprocin left which is the highest dose i had ingested,
my typical Methylone dose ranges 125 - 160 mg with one 40 - 50 mg booster.
Has anyone experiences taking both and how did it go?
 
5-meo-mipt & methylone combo ended up in hospitalization of one dude on erowid. be careful
do you mean the report with the powder that was sold as methylone, but was actually a mixture of 60% methylone and 38% 5-MeO-Mipt? well, obviously this was just a massive overdose of 5-MeO-MiPT.

4-ho-mipt is rather different from 5-MeO-MiPT pharmacologically; the latter has significant vasoconstrictor activity and is an SSRI.
really, 5-MeO-MiPT acts as serotonin reuptake inhibitor? can you give a source to that claim? is the same true for other 5-MeO-substituted tryptamines?
 
Last edited:
really, 5-MeO-MiPT acts as serotonin reuptake inhibitor? can you give a source to that claim? is the same true for other 5-MeO-substituted tryptamines?

I'm no scientist and I really have no idea, but it sure feels like it. Especially 5meodmt, for me.
 
^^ Then why would you say it in such a manner as to imply some sort of validity. The 5-meos seem more dangerous than their 4-sub counterparts, sure, but I don't know about SSRI properties, don't know about that at all.
 
I once took 333mg of Methylone on top of 15mg 4-HO-MIPT with two friends. It was probably one of my most remarkable experiences with psychedelics so far. No bad reactions besides significant vasoconstriction due to the high dose of Methylone. The synergetic effetcs were simply amazing. A long lasting ecstatic experience full of bliss, singing and dancing.

Concerning 5-MeO-MIPT and Methylone:
I also once tested 100mg of Methylone in combination with 8mg 5-MeO-MIPT. I was well informed about possible complications... but what actually happened was my most frightening experience with drugs so far. Severe vasoconstriction, extremely fast pulse rate >160. Had problems breathing and a tight chest aswell as a very concerning unusual headache and hyperthermia. I was able to breathe but it seemed that breathing had no effect on my blood oxygen level. Everything felt wrong in my body... It was coming in waves for several hours. Nearly normal pulse for 10 minutes and then suddenly an increasing heart rate up to life-threatening heights. Sometimes a heart beat was missed following two beats with doubled speed and so on. I was convinced this was going to be the end.

I took the Methylone when the main effects began wearing off. Probably t+5h - so I didn't expect big problems. I called an emergency facility due to the concern I could lose consciousness and would probably die. Unfortunately I didn't have a benzodiazepine on hand so I was forced to decide whether I should ask for an ambulance or try to keep calm and concentrate on breathing and hydration. The doctor tried to convince me to immediately go to hospital as he thought I might have a serotonin syndrome.

During all of this I had strong visuals and a psychedelic state of mind which didn't leave the following 2 weeks. As I get a regular MRI scan due to my cancer history my organs were checked aswell as my heart was and no damage was detected.
 
Ive tried this combination before. I took 20mg of 4-ho-mipt and 150mg of methylone. Its a safe combo unless you take too much methylone or take a medication that interacts badly with methylone (ex. An ssri).
 
I've done it, it's a very euphoric combo - but in my opinion Methylone overpowered the trippy effects of 4-HO-MiPT.
 
I rather enjoyed mephedrone and 4-HO-MiPT, for what it's worth. Woo sparkly.
 
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