best drugs to potentiate opana 15mg half moons?

[srs1980]

From other post on here you should know that i learned my lesson with opana when i first tried it(sure i overdosed) but now i think ive learned how to gradually build my tolerance and help my pain without killing myself. i do take 1 benadryl about 45 minutes before snorting a line of opana, which id say my lines range from around 3mg to 3.5mg at a time. i never do a whole 15 at once. anyways the benadryl helps with the itching and digging problems but i was wondering is there anything else i could take to potentiate or make it more euphoric. just trying to get the most outta my meds like everyone should do, and like everyone tries to do without asking properly, which leads to death and other horrible consequences. if im wrong by asking this question then so be it....dont reply or judge, but you wanna help me and give me suggestions since i have so little experience with the drug opana than your advice and posts are more than welcome. thank you bluelight for being there for us addicts which im not afraid to admit im one but i also have horrible pain issues and a history of back degenerative disk disease, rhuematoid arthritis, which i know i spelled wrong and so on from car wrecks and other accidents. i appreciate the help and advice bluelight has given me over the years, atleast the ones that give the good advice and dont judge and smartass around. i just want to learn about my meds, noone elses, so any help is appreciated.

 

[tricomb]

If you want to potentiate opana, I would not turned to drugs, I would look into eating a high-fat meal about 20 minutes before you insufflate your oxymorphone, it can raise plasma levels of oxymorphone in the bloodstream by up to 57% if I remember correctly.

There are other drugs that people routinely combine for "potentiation" rather, (although mostly synergism) such as:

Alcohol (extremely dangerous, can either lower or DRASTICALLY raise serum levels of oxymorphone in the bloodstream, its extremely variable, from -30% to +270% IIRC, do not combine opana with alcohol, it's way too variable), benzodiazepines (also extremely dangerous, does not affect oxymorphone levels, but the added CNS depression is often fatal, it will severely slow your breathing, by no means should you consider adding in benzodiazepines), and other CNS depressants (Soma, muscle relaxers, sedatives, sleeping pills, lyrica, gabapentin, random things, etc).

Please be extremely careful not to mix extremely potent CNS depressants.

In vitro studies show no effect of alcohol on the release of oxymorphone ER from the matrix; however, a volunteer study (Endo Pharmaceuticals 2007) showed that following the concomitant administration of 240 mL of 20% ethanol, the Cmax increased on average by 31%, with a wide range of variation. Thus, as with all opioids, consumption of alcohol beverages should be avoided. A volunteer study in healthy individuals showed that when oxymorphone was taken with a high-fat meal, the Cmax was increased by 38% compared with fasted volunteers (Endo Pharmaceuticals 2007). It is recommended to take oxymorphone on an empty stomach. As with many medications, plasma levels of oxymorphone were found to be higher (40%) in elderly than younger subjects. There is no known gender effect on the pharmacokinetics of oxymorphone.

(source)

If you want to potentiate it, maybe try the high fat meal, but please don't add in alcohol or benzodiazepines, it's not worth the risk.

 

[srs1980]

If you want to potentiate opana, I would not turned to drugs, I would look into eating a high-fat meal about 20 minutes before you insufflate your oxymorphone, it can raise plasma levels of oxymorphone in the bloodstream by up to 57% if I remember correctly.

There are other drugs that people routinely combine for "potentiation" rather, (although mostly synergism) such as:

Alcohol (extremely dangerous, can either lower or DRASTICALLY raise serum levels of oxymorphone in the bloodstream, its extremely variable, from -30% to +270% IIRC, do not combine opana with alcohol, it's way too variable), benzodiazepines (also extremely dangerous, does not affect oxymorphone levels, but the added CNS depression is often fatal, it will severely slow your breathing, by no means should you consider adding in benzodiazepines), and other CNS depressants (Soma, muscle relaxers, sedatives, sleeping pills, lyrica, gabapentin, random things, etc).

Please be extremely careful not to mix extremely potent CNS depressants.



(source)

If you want to potentiate it, maybe try the high fat meal, but please don't add in alcohol or benzodiazepines, it's not worth the risk.

The only thing about eating the high fat meals which believe me i have no problem with that lol im 6'1 280lbs is that after i eat and snort my line like i said usually 3 to 3.5 mg line but ive been doing less today, probably about 2.5 mg a line, is that i get so damn sleepy with that full stomach. I might as well take ten valiums and rollover eat a temazepam and pass out for the night. I appreciate your reply and ive heard about the high fight meals they just make me so darn sleepy, that i was wondering if there was something else out there for me to try, and definately no alcohol, but i have to admit i have had some benzos throughout the day today on and off just like the opana lines. im gonna go eat about 6-7 slices of pizza and i guess get my nod on for the night and watch some football. IM SO GLAD FOOTBALL TIME HAS ARRIVED!! get my excitement. nothing like a buzz on Saturday and Sunday watching a great ballgame on t.v. and there should be some interesting storylines in the college ball world and nfl this year. college b-ball is a no brainer .............UNIVERSITY OF KENTUCKY RULEZ......say what you want about coach cal but he gets it done recruiting and he got it done on the court last year and since he has arrived at ky. sorry for off topic but i know there so many coach cal haterz around.......alll i can say is results baby!!!!! love you guys and be safe and if any other advice is available please feel free to post. thanks tricomb.